PMID- 38161340
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20240103
IS  - 1671-5411 (Print)
IS  - 1671-5411 (Linking)
VI  - 20
IP  - 12
DP  - 2023 Dec 28
TI  - Prescription patterns of antidiabetic and cardiovascular preventive medications 
      in community-dwelling older adults with type 2 diabetes mellitus: a 
      cross-sectional study.
PG  - 867-876
LID - 10.26599/1671-5411.2023.12.002 [doi]
AB  - OBJECTIVE: To describe trends in antidiabetics drug prescription patterns in 
      community-dwelling older adults with type 2 diabetes mellitus (T2DM) and to 
      evaluate the use of cardiovascular preventive medications among those diagnosed 
      with atherosclerotic cardiovascular disease (ASCVD). METHODS: This 
      cross-sectional, face-to-face interview study that comprised community-dwelling 
      older adults (>/= 65 years) diagnosed with T2DM. The study questionnaire included 
      the patients' demographics, clinical data, and current medication use. Patients 
      with established ASCVD were further classified into low (i.e., not receiving 
      evidence-based therapy or only one) and high (i.e., receiving at least two 
      evidence-based therapies) composite score groups. Bivariate analysis followed by 
      multivariable logistic regression analysis were performed to evaluate the 
      demographic/clinical characteristics associated with the use of antidiabetic 
      monotherapy/polytherapy and evidence-based pharmacotherapy. RESULTS: A total of 
      500 older adults were enrolled. The mean age of included participants was 73 +/- 7 
      years, 310 participants (62%) were males, and 385 participants (77.0%) had 
      established ASCVD. Antidiabetic monotherapy was reported in 251 participants 
      (50.2%), with metformin followed by sulfonylureas being the most commonly 
      prescribed drugs as monotherapy. The results of the multivariable analysis showed 
      that age [odds ratio (OR) = 0.89, 95% CI: 0.85-0.94, P < 0.001], obesity (OR = 
      4.18, 95% CI: 1.63-10.36, P = 0.003), hypertension (OR = 4.2, 95% CI: 1.22-7.66, 
      P = 0.04), and dyslipidemia (OR = 4.1, 95% CI: 1.28-8.30, P = 0.01), were 
      significantly associated with the prescription of cardiovascular preventive 
      medications. CONCLUSIONS: Only one in twenty-one participant with T2DM and ASCVD 
      collectively received three guideline-recommended therapies, indicating a 
      deficiency of utilization of cardiovascular preventive drugs.
CI  - (c) 2023 JGC All rights reserved; www.jgc301.com.
FAU - Chahine, Bahia
AU  - Chahine B
AD  - Lebanese International University, School of Pharmacy, Beirut, Lebanon.
FAU - Souheil, Farah Al
AU  - Souheil FA
AD  - Lebanese International University, School of Pharmacy, Beirut, Lebanon.
FAU - Hanna, Venise
AU  - Hanna V
AD  - Lebanese International University, School of Pharmacy, Beirut, Lebanon.
LA  - eng
PT  - Journal Article
PL  - China
TA  - J Geriatr Cardiol
JT  - Journal of geriatric cardiology : JGC
JID - 101237881
PMC - PMC10755210
EDAT- 2024/01/02 11:45
MHDA- 2024/01/02 11:46
PMCR- 2023/12/28
CRDT- 2024/01/01 04:04
PHST- 2024/01/02 11:46 [medline]
PHST- 2024/01/02 11:45 [pubmed]
PHST- 2024/01/01 04:04 [entrez]
PHST- 2023/12/28 00:00 [pmc-release]
AID - jgc-20-12-867 [pii]
AID - 10.26599/1671-5411.2023.12.002 [doi]
PST - ppublish
SO  - J Geriatr Cardiol. 2023 Dec 28;20(12):867-876. doi: 
      10.26599/1671-5411.2023.12.002.