PMID- 38163829
OWN - NLM
STAT- Publisher
LR  - 20240101
IS  - 0973-7693 (Electronic)
IS  - 0019-5456 (Linking)
DP  - 2024 Jan 2
TI  - Juvenile Idiopathic Arthritis.
LID - 10.1007/s12098-023-04939-5 [doi]
AB  - Juvenile idiopathic arthritis (JIA) is the most common rheumatic disease in 
      children. The International League of Associations for Rheumatology (ILAR) has 
      defined JIA as "arthritis of unknown etiology persisting for >/=6 wk with an onset 
      at <16 y of age, after excluding other causes of joint inflammation". Synovial 
      inflammation is the result of a complex interplay of aberrant immune systems 
      (both adaptive and innate) in a genetically susceptible individual, with possible 
      external stimuli/triggers. Diagnosis of JIA essentially remains clinical, and 
      laboratory investigations usually help to assess the severity of disease 
      activity. Few investigations like antinuclear antibodies (ANA), human leukocyte 
      antigen (HLA)-B27, and rheumatoid factor (RF) help to categorize or prognosticate 
      a child with JIA. Timely use of effective therapeutic interventions including 
      biological has shown good long-term outcomes of JIA.
CI  - (c) 2023. The Author(s), under exclusive licence to Dr. K C Chaudhuri Foundation.
FAU - Sudhakar, Murugan
AU  - Sudhakar M
AD  - Pediatric Rheumatology Division, Department of Pediatrics, Christian Medical 
      College, Vellore, 632004, Tamil Nadu, India.
FAU - Kumar, Sathish
AU  - Kumar S
AUID- ORCID: 0000-0003-2137-7475
AD  - Pediatric Rheumatology Division, Department of Pediatrics, Christian Medical 
      College, Vellore, 632004, Tamil Nadu, India. sathishkumar@cmcvellore.ac.in.
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20240102
PL  - India
TA  - Indian J Pediatr
JT  - Indian journal of pediatrics
JID - 0417442
SB  - IM
OTO - NOTNLM
OT  - Children
OT  - Chronic arthritis
OT  - Juvenile idiopathic arthritis
EDAT- 2024/01/02 11:45
MHDA- 2024/01/02 11:45
CRDT- 2024/01/01 23:04
PHST- 2023/08/10 00:00 [received]
PHST- 2023/10/05 00:00 [accepted]
PHST- 2024/01/02 11:45 [medline]
PHST- 2024/01/02 11:45 [pubmed]
PHST- 2024/01/01 23:04 [entrez]
AID - 10.1007/s12098-023-04939-5 [pii]
AID - 10.1007/s12098-023-04939-5 [doi]
PST - aheadofprint
SO  - Indian J Pediatr. 2024 Jan 2. doi: 10.1007/s12098-023-04939-5.