PMID- 38166440
OWN - NLM
STAT- MEDLINE
DCOM- 20240117
LR  - 20240215
IS  - 1520-5827 (Electronic)
IS  - 0743-7463 (Linking)
VI  - 40
IP  - 2
DP  - 2024 Jan 16
TI  - Molecular Design and Controlled Self-Assembly of Copolymers as Core-Shell-Corona 
      Nanoparticles for Smarter Tumor Treatment.
PG  - 1143-1149
LID - 10.1021/acs.langmuir.3c02032 [doi]
AB  - Copolymer-based core-shell-corona nanoparticles have attracted more interest for 
      tumor chemotherapy, owing to their unique multifunctionality benefiting from 
      their unique multilevel topological structure in comparison with the conventional 
      core-shell ones. Here, the recent progress in such core-shell-corona 
      nanoparticle-based drug delivery systems (DDSs) in tumor chemotherapy was 
      reviewed, focusing on additive functionality of the shell layer for controlled 
      drug release performance from the viewpoints of the molecular design and 
      controlled self-assembly, such as stimuli-responsive gatekeepers, independent 
      loading of active substances, and so on. Moreover, future perspectives have been 
      prospected for smarter tumor treatment.
FAU - Liu, Peng
AU  - Liu P
AUID- ORCID: 0000-0003-1198-4925
AD  - State Key Laboratory of Applied Organic Chemistry, College of Chemistry and 
      Chemical Engineering, Lanzhou University, Lanzhou730000, China.
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20240103
PL  - United States
TA  - Langmuir
JT  - Langmuir : the ACS journal of surfaces and colloids
JID - 9882736
RN  - 80168379AG (Doxorubicin)
RN  - 0 (Polymers)
SB  - IM
MH  - Humans
MH  - Doxorubicin/chemistry
MH  - Polymers/chemistry
MH  - *Neoplasms/drug therapy
MH  - *Nanoparticles/chemistry
MH  - Drug Delivery Systems
EDAT- 2024/01/03 09:44
MHDA- 2024/01/17 06:42
CRDT- 2024/01/03 08:56
PHST- 2024/01/17 06:42 [medline]
PHST- 2024/01/03 09:44 [pubmed]
PHST- 2024/01/03 08:56 [entrez]
AID - 10.1021/acs.langmuir.3c02032 [doi]
PST - ppublish
SO  - Langmuir. 2024 Jan 16;40(2):1143-1149. doi: 10.1021/acs.langmuir.3c02032. Epub 
      2024 Jan 3.