PMID- 38178316
OWN - NLM
STAT- Publisher
LR  - 20240105
IS  - 2380-0194 (Electronic)
IS  - 2380-0186 (Linking)
DP  - 2024 Jan 5
TI  - Does Preoperative Back Pain Impact Patient-reported Outcomes in Patients 
      Undergoing Minimally Invasive Transforaminal Lumbar Interbody Fusion for Isthmic 
      Spondylolisthesis?
LID - 10.1097/BSD.0000000000001568 [doi]
AB  - STUDY DESIGN: Retrospective review. OBJECTIVE: To determine postoperative 
      clinical outcomes in patients undergoing minimally invasive (MIS) transforaminal 
      lumbar interbody fusion (TLIF) for isthmic spondylolisthesis (IS). BACKGROUND: 
      Few studies have examined the postoperative clinical trajectory in patients 
      undergoing MIS-TLIF specifically for IS. METHODS: Patients were separated into 
      two cohorts based on the previously defined Visual Analog Scale (VAS) back pain 
      (BP) for severe pain: VAS-BP <7 and VAS-BP >/=7. Patient-reported outcome measures 
      (PROMs) of Patient-Reported Outcomes Measurement Information System-physical 
      function (PF), 12-item Short Form (SF-12) Physical/Mental Component Score, 
      Patient Health Questionnaire-9, VAS-BP, VAS leg pain, and Oswestry Disability 
      Index were collected preoperatively and up to 2-year postoperatively. Minimum 
      clinically important difference (MCID) was calculated through previously defined 
      thresholds. RESULTS: A total of 160 patients were recorded, with 58 patients in 
      the VAS-BP <7 cohort. The VAS-BP <7 cohort demonstrated significant improvement 
      in all PROMs at one or more postoperative time points. The VAS-BP >/=7 demonstrated 
      significant improvement at 3 or more postoperative time points in all PROMs 
      except for SF-12 Mental Component Score. The VAS-BP <7 cohort reported 
      significantly superior preoperative and postoperative PROMs in all domains, 
      except for SF-12 Physical Component Score. The VAS-BP >/=7 cohort had higher MCID 
      achievement rates at one or more time points in multiple PROMs. CONCLUSION: 
      Patients undergoing MIS-TLIF for IS demonstrated significant postoperative 
      improvement in PF, mental function, pain, and disability outcomes independent of 
      preoperative severity of BP. Patients with lower preoperative BP demonstrated 
      superior outcomes in PF, mental function, pain, and disability. However, patients 
      with greater preoperative BP achieved higher rates of MCID in mental function, 
      BP, and disability outcomes. Patients with greater severity of preoperative BP 
      undergoing MIS-TLIF for IS may experience greater rates of clinically relevant 
      improvement in mental function, BP, and disability outcomes.
CI  - Copyright (c) 2024 Wolters Kluwer Health, Inc. All rights reserved.
FAU - Nie, James W
AU  - Nie JW
AD  - Department of Orthopedic Surgery, Rush University Medical Center, Chicago, IL.
FAU - Hartman, Timothy J
AU  - Hartman TJ
FAU - Zheng, Eileen
AU  - Zheng E
FAU - Oyetayo, Omolabake O
AU  - Oyetayo OO
FAU - MacGregor, Keith R
AU  - MacGregor KR
FAU - Federico, Vincent P
AU  - Federico VP
FAU - Massel, Dustin H
AU  - Massel DH
FAU - Sayari, Arash J
AU  - Sayari AJ
FAU - Singh, Kern
AU  - Singh K
LA  - eng
PT  - Journal Article
DEP - 20240105
PL  - United States
TA  - Clin Spine Surg
JT  - Clinical spine surgery
JID - 101675083
SB  - IM
COIS- The authors declare no conflict of interest.
EDAT- 2024/01/05 06:43
MHDA- 2024/01/05 06:43
CRDT- 2024/01/05 00:03
PHST- 2023/01/20 00:00 [received]
PHST- 2023/11/29 00:00 [accepted]
PHST- 2024/01/05 06:43 [medline]
PHST- 2024/01/05 06:43 [pubmed]
PHST- 2024/01/05 00:03 [entrez]
AID - 01933606-990000000-00250 [pii]
AID - 10.1097/BSD.0000000000001568 [doi]
PST - aheadofprint
SO  - Clin Spine Surg. 2024 Jan 5. doi: 10.1097/BSD.0000000000001568.