PMID- 38185693
OWN - NLM
STAT- MEDLINE
DCOM- 20240311
LR  - 20240311
IS  - 1432-2099 (Electronic)
IS  - 0301-634X (Linking)
VI  - 63
IP  - 1
DP  - 2024 Mar
TI  - Evaluation of organ dose using size-specific dose estimation (SSDE) and related 
      cancer risk due to chest CT scan during the COVID-19 pandemic.
PG  - 27-37
LID - 10.1007/s00411-023-01056-x [doi]
AB  - This study aimed to estimate lung and breast doses for individual patients using 
      the size-specific dose estimate (SSDE) method, as well as calculating effective 
      doses, in patients who underwent chest CT scans during the COVID-19 pandemic. 
      Cancer risk incidence was estimated using excess relative risk (ERR), excess 
      absolute risk (EAR), and lifetime attributable risk (LAR) models from the 
      Biological Effects of Ionizing Radiation Report VII (BEIR-VII). Data from about 
      570 patients who underwent CT scans for COVID-19 screening were utilized for this 
      study. Using the header of the CT images in a Python script, SSDE and effective 
      dose were calculated for each patient. The SSDE obtained by water equivalent 
      effective diameter (wSSDE) was considered as lung and breast dose, and applied in 
      organ-specific cancer risk estimation. The mean wSSDE value for females 
      (13.3 mGy) was slightly higher than that for males (13.1 mGy), but the difference 
      was not statistically significant (P value = 0.41). No significant differences 
      were observed between males and females in terms of calculated EAR and ERR for 
      lung cancer at 5 and 30 years after exposure (P value = 0.47, 0.46, 
      respectively). Similarly, there was no significant difference in lung cancer LAR 
      values between females and males (P value = 0.48). The results also indicated a 
      decrease in LAR values for both lung and breast cancers with increasing exposure 
      age. In accordance with the ALARA (as low as reasonably achievable) principle, it 
      is important for medical staff and the general public to consider the benefits of 
      CT imaging in detecting such infections. Additionally, imaging medical physicists 
      and CT scan experts should optimize imaging protocols and strike a balance 
      between image quality for detecting abnormalities and radiation dose, all while 
      adhering to the ALARA principle.
CI  - (c) 2024. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, 
      part of Springer Nature.
FAU - Robatjazi, Mostafa
AU  - Robatjazi M
AD  - Department of Medical Physics and Radiological Sciences, Sabzevar University of 
      Medical Sciences, Sabzevar, Iran.
AD  - Non-Communicable Disease Research Center, Sabzevar University of Medical 
      Sciences, Sabzevar, Iran.
FAU - Moayed, Mahdis
AU  - Moayed M
AD  - Department of Medical Physics and Radiological Sciences, Sabzevar University of 
      Medical Sciences, Sabzevar, Iran.
FAU - Baghani, Hamid Reza
AU  - Baghani HR
AD  - Department of Physics, Hakim Sabzevari University, Sabzevar, Iran. 
      Hamidreza.baghani@gmail.com.
FAU - Molazadeh, Mikaeil
AU  - Molazadeh M
AD  - Department of Medical Physics, Tabriz University of Medical Sciences, Tabriz, 
      Iran.
FAU - Shomoossi, Nematullah
AU  - Shomoossi N
AD  - School of Medicine, Sabzevar University of Medical Sciences, Sabzevar, Iran.
LA  - eng
GR  - 400151/Sabzevar University of Medical Sciences/
PT  - Journal Article
DEP - 20240107
PL  - Germany
TA  - Radiat Environ Biophys
JT  - Radiation and environmental biophysics
JID - 0415677
SB  - IM
MH  - Male
MH  - Female
MH  - Humans
MH  - Radiation Dosage
MH  - Pandemics
MH  - *COVID-19/epidemiology/etiology
MH  - Tomography, X-Ray Computed/adverse effects
MH  - Risk Factors
MH  - *Breast Neoplasms/diagnostic imaging/epidemiology/etiology
MH  - *Lung Neoplasms/etiology
OTO - NOTNLM
OT  - COVID-19
OT  - CT scan
OT  - Cancer risk
OT  - Effective dose
OT  - Organ dose
OT  - SSDE
EDAT- 2024/01/08 00:42
MHDA- 2024/03/11 06:44
CRDT- 2024/01/07 23:35
PHST- 2022/12/23 00:00 [received]
PHST- 2023/12/08 00:00 [accepted]
PHST- 2024/03/11 06:44 [medline]
PHST- 2024/01/08 00:42 [pubmed]
PHST- 2024/01/07 23:35 [entrez]
AID - 10.1007/s00411-023-01056-x [pii]
AID - 10.1007/s00411-023-01056-x [doi]
PST - ppublish
SO  - Radiat Environ Biophys. 2024 Mar;63(1):27-37. doi: 10.1007/s00411-023-01056-x. 
      Epub 2024 Jan 7.