PMID- 38186438
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20240109
IS  - 2168-8184 (Print)
IS  - 2168-8184 (Electronic)
IS  - 2168-8184 (Linking)
VI  - 15
IP  - 12
DP  - 2023 Dec
TI  - Unveiling the Silent Struggle: A Teen's Battle With Heart Failure Masking 
      Takayasu Arteritis.
PG  - e50154
LID - 10.7759/cureus.50154 [doi]
LID - e50154
AB  - We hereby report a 17-year-old adolescent who presented with heart failure with 
      an underlying diagnosis of Takayasu arteritis. Her clinical complaints were 
      intermittent fever, claudication pain in the left upper limb, New York Heart 
      Association (NYHA) grade III dyspnea, and episodes of dizziness for the past two 
      years. On examination, she was unconscious, had absent peripheral pulses, and had 
      severe hypotension. Diagnostic investigations revealed anemia, deranged renal and 
      liver functions, cardiomegaly on chest X-rays, and severe coarctation of the 
      aorta on echocardiography. Further imaging with CT aortography highlighted 
      extensive arterial wall thickening. Laboratory findings included elevated 
      inflammatory markers and negative autoimmune and infectious markers, confirming 
      the diagnosis of large vessel vasculitis (Takayasu arteritis) with heart failure 
      with reduced ejection fraction (LVEF 20-25%) in NYHA class III. The patient was 
      managed with a combination of antihypertensive medications, diuretics, and 
      immunosuppressive therapy. Subsequent follow-up demonstrated improvement in heart 
      failure symptoms and inflammatory markers. This case emphasizes the challenging 
      diagnostic and therapeutic considerations in managing Takayasu arteritis with 
      concurrent cardiovascular complications in the adolescent population.
CI  - Copyright (c) 2023, Barman et al.
FAU - Barman, Manidipa
AU  - Barman M
AD  - Pediatrics, All India Institute of Medical Sciences, Rishikesh, Rishikesh, IND.
FAU - Aggarwal, Sanchit
AU  - Aggarwal S
AD  - Pediatrics, All India Institute of Medical Sciences, Rishikesh, Rishikesh, IND.
FAU - Chakrabarti, Sarthak
AU  - Chakrabarti S
AD  - Pediatrics, All India Institute of Medical Sciences, Rishikesh, Rishikesh, IND.
FAU - Mandal, Sharusa
AU  - Mandal S
AD  - Pediatrics, All India Institute of Medical Sciences, Rishikesh, Rishikesh, IND.
FAU - Mishra, Anand S
AU  - Mishra AS
AD  - Pediatrics, All India Institute of Medical Sciences, Rishikesh, Rishikesh, IND.
FAU - Chaurasia, Anjali
AU  - Chaurasia A
AD  - Pediatrics, All India Institute of Medical Sciences, Rishikesh, Rishikesh, IND.
FAU - Gupta, Diksha
AU  - Gupta D
AD  - Pediatrics, All India Institute of Medical Sciences, Rishikesh, Rishikesh, IND.
FAU - Panda, Prateek Kumar
AU  - Panda PK
AD  - Pediatrics, All India Institute of Medical Sciences, Rishikesh, Rishikesh, IND.
LA  - eng
PT  - Case Reports
DEP - 20231208
PL  - United States
TA  - Cureus
JT  - Cureus
JID - 101596737
PMC - PMC10771626
OTO - NOTNLM
OT  - adolescent girl
OT  - congestive heart failure
OT  - dilated cardiomyopathy
OT  - mikito takayasu
OT  - takayasu arteritis
COIS- The authors have declared that no competing interests exist.
EDAT- 2024/01/08 06:42
MHDA- 2024/01/08 06:43
PMCR- 2023/12/08
CRDT- 2024/01/08 04:25
PHST- 2023/12/08 00:00 [accepted]
PHST- 2024/01/08 06:43 [medline]
PHST- 2024/01/08 06:42 [pubmed]
PHST- 2024/01/08 04:25 [entrez]
PHST- 2023/12/08 00:00 [pmc-release]
AID - 10.7759/cureus.50154 [doi]
PST - epublish
SO  - Cureus. 2023 Dec 8;15(12):e50154. doi: 10.7759/cureus.50154. eCollection 2023 
      Dec.