PMID- 38190436
OWN - NLM
STAT- MEDLINE
DCOM- 20240327
LR  - 20240327
IS  - 1362-3095 (Electronic)
IS  - 0955-3002 (Linking)
VI  - 100
IP  - 4
DP  - 2024
TI  - High-density polyethylene (HDPE)-incorporated boron carbide and boric acid 
      nanoparticles as a nanoshield of photoneutrons from medical linear accelerators.
PG  - 609-618
LID - 10.1080/09553002.2023.2295964 [doi]
AB  - PURPOSE: The current study aimed to investigate boron carbide and boric acid 
      nanoparticles (NPs) as absorbents for thermal neutrons and high-density 
      polyethylene (HDPE) as a substrate and neutron moderator for fast neutrons. The 
      goal was to assess the performance of boron carbide and boric acid NPs based on 
      HDPE as a nanoshield of photoneutrons from medical linear accelerators. MATERIALS 
      AND METHODS: This study was conducted in two parts of simulation and practice. 
      The Monte Carlo (MC) simulation involved modeling and verification of the 
      single-layer, double-layer, and combined nanoshields by selecting nanomaterials 
      and substrates and, finally, calculating the macroscopic cross-sections. The 
      practical part involved manufacturing nanoshields based on the simulation results 
      and evaluating the manufactured nanocomposites via experimental measurements. 
      RESULTS: MC simulation results with an uncertainty of less than 1% showed that 
      for the monolayer samples, the best result belonged to boron carbide at a 
      concentration of 10% and a macroscopic cross-section of 0.933 cm(-1). At a 
      concentration of 20%, the highest value among the double-layer samples was 
      0.936 cm(-1) and for the combined samples, this value was 0.928 cm(-1). Boron 
      carbide single-layer nanocomposites at a 10% concentration, as well as the 
      bilayer nanoshield of 10% boron carbide and 20% boric acid performed well; 
      however, the best performance belonged to the nanoshield with a macroscopic 
      cross-section of 0.960 and the combination containing 5% boron carbide and 10% 
      boric acid. CONCLUSIONS: The research suggests that utilizing boron carbide and 
      boric acid nanoshields in combination with HDPE holds promise as a viable 
      approach to protecting from the photoneutrons. Further exploration of these 
      nanocomposite shields and their practical applications is warranted, with the 
      potential to yield significant advancements in radiation therapy safety and 
      efficacy.
FAU - Vegari, Ali
AU  - Vegari A
AD  - Department of Medical Physics, Faculty of Medicine, Urmia University of Medical 
      Sciences, Urmia, Iran.
FAU - Abdisaray, Akbar
AU  - Abdisaray A
AD  - Department of Physics, Faculty of Sciences, Urmia University, Urmia, Iran.
FAU - Mostafanejad, Kamal
AU  - Mostafanejad K
AD  - Omid Research and Treatment Center, Urmia, Iran.
FAU - Jabbari, Nasrollah
AU  - Jabbari N
AUID- ORCID: 0000-0003-3044-4609
AD  - Solid Tumor Research Center, Cellular and Molecular Medicine Institute, Urmia 
      University of Medical Sciences, Urmia, Iran.
LA  - eng
PT  - Journal Article
DEP - 20240108
PL  - England
TA  - Int J Radiat Biol
JT  - International journal of radiation biology
JID - 8809243
RN  - R57ZHV85D4 (boric acid)
RN  - 9002-88-4 (Polyethylene)
RN  - N9E3X5056Q (Boron)
RN  - 0 (Boron Compounds)
RN  - 0 (Boric Acids)
SB  - IM
MH  - Polyethylene
MH  - Boron
MH  - Boron Compounds
MH  - Neutrons
MH  - Particle Accelerators
MH  - Monte Carlo Method
MH  - *Nanoparticles
MH  - *Boron Neutron Capture Therapy/methods
MH  - *Boric Acids
OTO - NOTNLM
OT  - HDPE
OT  - Monte Carlo
OT  - Neutron nano-shielding
OT  - boric acid
OT  - boron carbide
OT  - linear accelerator
EDAT- 2024/01/08 18:42
MHDA- 2024/03/27 06:43
CRDT- 2024/01/08 13:53
PHST- 2024/03/27 06:43 [medline]
PHST- 2024/01/08 18:42 [pubmed]
PHST- 2024/01/08 13:53 [entrez]
AID - 10.1080/09553002.2023.2295964 [doi]
PST - ppublish
SO  - Int J Radiat Biol. 2024;100(4):609-618. doi: 10.1080/09553002.2023.2295964. Epub 
      2024 Jan 8.