PMID- 38191139 OWN - NLM STAT- MEDLINE DCOM- 20240110 LR - 20240110 IS - 1881-6096 (Print) IS - 1881-6096 (Linking) VI - 76 IP - 1 DP - 2024 Jan TI - [Pathogenesis of MuSK Antibody-positive Myasthenia Gravis]. PG - 47-53 LID - 10.11477/mf.1416202557 [doi] AB - Long-term remission is rare in patients with myasthenia gravis (MG), and health-related quality of life is lower in patients with MG than in healthy individuals. Approximately 5% of patients with MG show positive results on muscle-specific kinase (MuSK) antibody testing and usually have severe symptoms, refractory disease, residual muscle atrophy, and poor prognosis. Recent studies that have investigated the pathogenesis of MuSK antibody-positive MG have reported contributors to treatment refractoriness in cases of MG. In this article, we review the most recent findings. FAU - Shigemoto, Kazuhiro AU - Shigemoto K AD - Tokyo Metropolitan Institute for Geriatrics and Gerontology. LA - jpn PT - English Abstract PT - Journal Article PT - Review PL - Japan TA - Brain Nerve JT - Brain and nerve = Shinkei kenkyu no shinpo JID - 101299709 SB - IM MH - Humans MH - *Quality of Life MH - Muscular Atrophy MH - *Myasthenia Gravis EDAT- 2024/01/09 00:42 MHDA- 2024/01/10 06:42 CRDT- 2024/01/08 19:53 PHST- 2024/01/10 06:42 [medline] PHST- 2024/01/09 00:42 [pubmed] PHST- 2024/01/08 19:53 [entrez] AID - 1416202557 [pii] AID - 10.11477/mf.1416202557 [doi] PST - ppublish SO - Brain Nerve. 2024 Jan;76(1):47-53. doi: 10.11477/mf.1416202557.