PMID- 38191653
OWN - NLM
STAT- MEDLINE
DCOM- 20240110
LR  - 20240111
IS  - 2045-2322 (Electronic)
IS  - 2045-2322 (Linking)
VI  - 14
IP  - 1
DP  - 2024 Jan 8
TI  - Longitudinal changes in the ganglion cell complex thickness in acute central 
      serous chorioretinopathy using spectral-domain optical coherence tomography.
PG  - 821
LID - 10.1038/s41598-023-50953-0 [doi]
LID - 821
AB  - In this retrospective longitudinal cohort study, we investigated the temporal 
      changes in the peripapillary retinal nerve fiber layer (pRNFL) and inner retinal 
      thickness in patients with acute central serous chorioretinopathy (CSC) using 
      spectral-domain optical coherence tomography (SD-OCT). We followed up with these 
      patients for 6 months, and during this period, the thickness of the pRNFL and the 
      ganglion cell complex (GCC) in CSC patients were compared with the eyes of normal 
      healthy individuals. The study also examined the correlation between the pRNFL 
      thickness, GCC thickness, and visual acuity. The research sample consisted of 67 
      patients (43 male and 24 female) with an average age of 49.72 +/- 9.87 years. The 
      initial findings showed no significant differences in the pRNFL and GCC thickness 
      between the study and fellow eye, study and normal healthy eyes, and fellow and 
      normal healthy eyes. There was no significant difference in the pRNFL and GCC 
      thickness when comparing the study eye with the fellow eye for 6 months. In the 
      study eye, no significant difference was observed when comparing the initial GCC 
      and pRNFL thickness with those at 1, 3, and 6 months. Visual acuity improved 
      significantly from 0.18 +/- 0.23 logMAR to 0.04 +/- 0.06 logMAR (p < 0.001). The GCC 
      and pRNFL thickness did not significantly affect visual acuity. In conclusion, 
      acute CSC patients did not show significant changes in the pRNFL and inner 
      retinal thickness, suggesting that the GCC and pRNFL do not substantially 
      influence the short-term visual prognosis in these patients.
CI  - (c) 2024. The Author(s).
FAU - Kim, Dong Ik
AU  - Kim DI
AD  - Department of Ophthalmology, Hangil Eye Hospital, 35 Bupyeong-daero, Bupyeong-gu, 
      Incheon, 21388, South Korea.
AD  - Department of Ophthalmology, Catholic Kwandong University College of Medicine, 
      Incheon, South Korea.
FAU - Bae, Ki Woong
AU  - Bae KW
AD  - Department of Ophthalmology, Nowon Eulji Medical Center, Seoul, South Korea.
AD  - Department of Ophthalmology, Eulji University College of Medicine, Seoul, South 
      Korea.
FAU - Jang, Kyuhwan
AU  - Jang K
AD  - Department of Ophthalmology, Hangil Eye Hospital, 35 Bupyeong-daero, Bupyeong-gu, 
      Incheon, 21388, South Korea.
AD  - Department of Ophthalmology, Catholic Kwandong University College of Medicine, 
      Incheon, South Korea.
FAU - Hwang, Daniel Duck-Jin
AU  - Hwang DD
AD  - Department of Ophthalmology, Hangil Eye Hospital, 35 Bupyeong-daero, Bupyeong-gu, 
      Incheon, 21388, South Korea. daniel.dj.hwang@gmail.com.
AD  - Department of Ophthalmology, Catholic Kwandong University College of Medicine, 
      Incheon, South Korea. daniel.dj.hwang@gmail.com.
LA  - eng
PT  - Journal Article
DEP - 20240108
PL  - England
TA  - Sci Rep
JT  - Scientific reports
JID - 101563288
SB  - IM
MH  - Humans
MH  - Female
MH  - Male
MH  - Adult
MH  - Middle Aged
MH  - *Central Serous Chorioretinopathy/diagnostic imaging
MH  - Tomography, Optical Coherence
MH  - Longitudinal Studies
MH  - Retrospective Studies
MH  - Retina/diagnostic imaging
MH  - Acute Disease
PMC - PMC10774394
COIS- The authors declare no competing interests.
EDAT- 2024/01/09 00:42
MHDA- 2024/01/10 06:42
PMCR- 2024/01/08
CRDT- 2024/01/08 23:53
PHST- 2023/05/30 00:00 [received]
PHST- 2023/12/28 00:00 [accepted]
PHST- 2024/01/10 06:42 [medline]
PHST- 2024/01/09 00:42 [pubmed]
PHST- 2024/01/08 23:53 [entrez]
PHST- 2024/01/08 00:00 [pmc-release]
AID - 10.1038/s41598-023-50953-0 [pii]
AID - 50953 [pii]
AID - 10.1038/s41598-023-50953-0 [doi]
PST - epublish
SO  - Sci Rep. 2024 Jan 8;14(1):821. doi: 10.1038/s41598-023-50953-0.