PMID- 38192308 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20240110 IS - 2046-2069 (Electronic) IS - 2046-2069 (Linking) VI - 14 IP - 3 DP - 2024 Jan 3 TI - Preparation of carbon quantum dot fluorescent probe from waste fruit peel and its use for the detection of dopamine. PG - 1813-1821 LID - 10.1039/d3ra06799h [doi] AB - Carbon quantum dots (CQDs), as a new type of fluorescent nanomaterial, are widely used in the detection of small molecules. Abnormal dopamine secretion can lead to diseases such as Parkinson's disease and schizophrenia. Therefore, it is highly significant to detect dopamine levels in the human body. Using discarded fruit peels to prepare carbon quantum dots can achieve the reuse of kitchen waste, reduce pollution, and create value. Nitrogen-doped carbon quantum dots (N-CQDs) were prepared using the hydrothermal method, with orange peel as the raw material. The fluorescence quantum yield of N-CQDs reached a high value of 35.37% after optimizing the temperature, reaction time, and ethylenediamine dosage. N-CQDs were characterized using various techniques, including ultraviolet visible (UV-vis) spectroscopy, fluorescence spectrophotometer (PL), transmission electron microscopy (TEM), and Fourier transform infrared spectroscopy (FT-IR). These analyses confirmed the successful doping of nitrogen in the CQDs. The DA concentration ranged from 0 to 300 mumol L(-1), and the linear equation for fluorescence quenching of N-CQDs was F/F(0) = -0.0056c + 0.98647, with an R(2) value of 0.99071. The detection limit was 0.168 mumol L(-1). The recovery and precision of dopamine in rabbit serum were 98% to 103% and 2% to 6%, respectively. The prepared N-CQDs could be used as a fluorescent probe to effectively detect DA. CI - This journal is (c) The Royal Society of Chemistry. FAU - Han, Li AU - Han L AD - School of Biological and Chemical Engineering, Qilu Institute of Technology Jinan 250200 P. R. China hanli0226@163.com yejj0727@qlit.edu.cn yingwang20191231@163.com. FAU - Guo, Yingkai AU - Guo Y AD - Jinan Engineering Consulting Institute Jinan China. FAU - Zhang, Haohao AU - Zhang H AD - School of Biological and Chemical Engineering, Qilu Institute of Technology Jinan 250200 P. R. China hanli0226@163.com yejj0727@qlit.edu.cn yingwang20191231@163.com. FAU - Wang, Zifan AU - Wang Z AD - School of Biological and Chemical Engineering, Qilu Institute of Technology Jinan 250200 P. R. China hanli0226@163.com yejj0727@qlit.edu.cn yingwang20191231@163.com. FAU - Zhang, Fan AU - Zhang F AD - School of Biological and Chemical Engineering, Qilu Institute of Technology Jinan 250200 P. R. China hanli0226@163.com yejj0727@qlit.edu.cn yingwang20191231@163.com. FAU - Wang, Yiran AU - Wang Y AD - School of Biological and Chemical Engineering, Qilu Institute of Technology Jinan 250200 P. R. China hanli0226@163.com yejj0727@qlit.edu.cn yingwang20191231@163.com. FAU - Li, Xingqi AU - Li X AD - School of Biological and Chemical Engineering, Qilu Institute of Technology Jinan 250200 P. R. China hanli0226@163.com yejj0727@qlit.edu.cn yingwang20191231@163.com. FAU - Wang, Ying AU - Wang Y AD - School of Biological and Chemical Engineering, Qilu Institute of Technology Jinan 250200 P. R. China hanli0226@163.com yejj0727@qlit.edu.cn yingwang20191231@163.com. FAU - Ye, Jiajia AU - Ye J AUID- ORCID: 0000-0002-6550-300X AD - School of Biological and Chemical Engineering, Qilu Institute of Technology Jinan 250200 P. R. China hanli0226@163.com yejj0727@qlit.edu.cn yingwang20191231@163.com. LA - eng PT - Journal Article DEP - 20240108 PL - England TA - RSC Adv JT - RSC advances JID - 101581657 PMC - PMC10772540 COIS- There are no conflicts to declare. EDAT- 2024/01/09 06:42 MHDA- 2024/01/09 06:43 PMCR- 2024/01/08 CRDT- 2024/01/09 03:45 PHST- 2023/10/06 00:00 [received] PHST- 2023/12/26 00:00 [accepted] PHST- 2024/01/09 06:43 [medline] PHST- 2024/01/09 06:42 [pubmed] PHST- 2024/01/09 03:45 [entrez] PHST- 2024/01/08 00:00 [pmc-release] AID - d3ra06799h [pii] AID - 10.1039/d3ra06799h [doi] PST - epublish SO - RSC Adv. 2024 Jan 8;14(3):1813-1821. doi: 10.1039/d3ra06799h. eCollection 2024 Jan 3.