PMID- 38193085
OWN - NLM
STAT- MEDLINE
DCOM- 20240110
LR  - 20240328
IS  - 1664-3224 (Electronic)
IS  - 1664-3224 (Linking)
VI  - 14
DP  - 2023
TI  - Food allergy spectrum in the tropic: clinical and epidemiological profiles in a 
      colombian hospital. A cross-sectional study.
PG  - 1291275
LID - 10.3389/fimmu.2023.1291275 [doi]
LID - 1291275
AB  - INTRODUCTION: Food allergy affects 2-10% of the general population; it is more 
      frequent among children than among adults, and it is one of the leading causes of 
      anaphylaxis. Diagnosis of food allergy requires a detailed medical history, skin 
      tests, specific immunoglobulin E (IgE) tests for the food involved, and an oral 
      challenge as final confirmation. OBJECTIVES: This study aimed to describe the 
      clinical and epidemiological characteristics of patients who underwent oral food 
      challenges for suspected food allergies in a reference center in Colombia. 
      METHODOLOGY: An observational, descriptive, cross-sectional and retrospective 
      study was conducted. Data were retrospectively collected from patients who were 
      evaluated in the allergology service and suspected of food allergy from 2011 to 
      2018. Quantitative variables are presented as means or medians depending on the 
      normality of the distribution (assessed by the Shapiro-Wilk test), and 
      categorical variables are presented as frequencies and percentages. RESULTS: A 
      total of 215 controlled open challenges were performed on 176 patients, most of 
      whom were children (69%). Thirty-one patients (17%) required another oral 
      challenge with a second food, and 11 (6.25%) required another oral challenge with 
      three foods. Twelve oral challenges (5.58%) were positive. Of these, five 
      challenges were positive for cow's milk, 5 were positive for shrimp, and 2 were 
      positive for legumes (peanuts and lentils). CONCLUSION: The frequency of 
      confirmed food allergies and the profile of food allergies in our population 
      differs from that reported in other parts of the world.
CI  - Copyright (c) 2023 Olaya-Hernandez, Vasquez, Silva, Martinez-Betancur, Guerra, 
      Arias, Ramirez and Serrano.
FAU - Olaya-Hernandez, Manuela
AU  - Olaya-Hernandez M
AD  - Valle del Lili Foundation, Cali, Colombia.
AD  - Faculty of Health Sciences, ICESI University, Cali, Colombia.
FAU - Vasquez, Laura Del Mar
AU  - Vasquez LDM
AD  - Faculty of Health Sciences, ICESI University, Cali, Colombia.
FAU - Silva, Diana Lucia
AU  - Silva DL
AD  - Valle del Lili Foundation, Cali, Colombia.
AD  - Faculty of Health Sciences, ICESI University, Cali, Colombia.
FAU - Martinez-Betancur, Sofia
AU  - Martinez-Betancur S
AD  - Valle del Lili Foundation, Cali, Colombia.
FAU - Guerra, Maria
AU  - Guerra M
AD  - Valle del Lili Foundation, Cali, Colombia.
FAU - Arias, Oriana
AU  - Arias O
AD  - Valle del Lili Foundation, Cali, Colombia.
AD  - Faculty of Health Sciences, ICESI University, Cali, Colombia.
FAU - Ramirez, Luis Fernando
AU  - Ramirez LF
AD  - Valle del Lili Foundation, Cali, Colombia.
FAU - Serrano, Carlos Daniel
AU  - Serrano CD
AD  - Valle del Lili Foundation, Cali, Colombia.
LA  - eng
PT  - Comment
PT  - Journal Article
PT  - Observational Study
DEP - 20231219
PL  - Switzerland
TA  - Front Immunol
JT  - Frontiers in immunology
JID - 101560960
SB  - IM
CON - Allergol Immunopathol (Madr). 2015 Mar-Apr;43(2):185-95. PMID: 24207003
MH  - Adult
MH  - Child
MH  - Animals
MH  - Cattle
MH  - Female
MH  - Humans
MH  - Cross-Sectional Studies
MH  - Colombia/epidemiology
MH  - Retrospective Studies
MH  - *Food Hypersensitivity/epidemiology
MH  - Hospitals
MH  - Seafood
PMC - PMC10773786
OTO - NOTNLM
OT  - food allergy
OT  - food allergy diagnosis
OT  - food hypersensitivity
OT  - food sensitization
OT  - immunoglobulin E
OT  - oral food challenges
COIS- The authors declare that the research was conducted in the absence of any 
      commercial or financial relationships that could be construed as a potential 
      conflict of interest.
EDAT- 2024/01/09 06:41
MHDA- 2024/01/10 06:42
PMCR- 2023/01/01
CRDT- 2024/01/09 04:01
PHST- 2023/09/08 00:00 [received]
PHST- 2023/11/29 00:00 [accepted]
PHST- 2024/01/10 06:42 [medline]
PHST- 2024/01/09 06:41 [pubmed]
PHST- 2024/01/09 04:01 [entrez]
PHST- 2023/01/01 00:00 [pmc-release]
AID - 10.3389/fimmu.2023.1291275 [doi]
PST - epublish
SO  - Front Immunol. 2023 Dec 19;14:1291275. doi: 10.3389/fimmu.2023.1291275. 
      eCollection 2023.