PMID- 38196045
OWN - NLM
STAT- MEDLINE
DCOM- 20240126
LR  - 20240206
IS  - 1708-0428 (Electronic)
IS  - 0960-8923 (Print)
IS  - 0960-8923 (Linking)
VI  - 34
IP  - 2
DP  - 2024 Feb
TI  - Effect of Sleeve Gastrectomy Versus One Anastomosis Gastric Bypass on 
      Postoperative Renal Function and the Urinary Monocyte Chemoattractant Protein-1 
      (MCP-1) Level.
PG  - 610-617
LID - 10.1007/s11695-023-07033-z [doi]
AB  - INTRODUCTION: Bariatric surgery has been the most effective treatment modality 
      for morbid obesity that reduces associated comorbidities and improves quality of 
      life. This study aims at evaluating and comparing the impact of two types of 
      bariatric surgery-laparoscopic sleeve gastrectomy (LSG) and one anastomosis 
      gastric bypass (OAGB)-on renal functions and urinary monocyte chemoattractant 
      protein-1 (MPC-1) levels in morbidly obese patients 3 months after surgery. 
      METHODS: This is a prospective study of 40 morbidly obese patients who underwent 
      bariatric surgery. Two types of bariatric surgery were done-laparoscopic sleeve 
      gastrectomy (LSG) (26 patients) and laparoscopic one anastomosis gastric bypass 
      (OAGB) (14 patients). The outcomes of the two procedures were compared in terms 
      of renal function parameters and the level of urinary MCP-1. RESULTS: There were 
      no statistically significant differences in the mean postoperative urinary MCP-1 
      (73.53 +/- 21.25, 75.43 +/- 26.17, P > 0.5), microalbuminuria (8.83 +/- 6.26, 
      10.02 +/- 8.6, P > 0.05), urinary creatinine (109.21 +/- 43.22, 99.19 +/- 48.65, 
      P > 0.05), MCP1/Cr ratio (0.78 +/- 0.36, 1.01 +/- 0.70, P > 0.05), eGFR 
      (100.32 +/- 9.54, 104.39 +/- 9.54, P > 0.05) in the cases who had either LSG 
      operation or OAGB operation. CONCLUSION: Bariatric surgery improves all 
      indicators of kidney malfunction and reduces the level of urinary MCP-1. Both 
      laparoscopic sleeve gastrectomy (LSG) and laparoscopic one anastomosis gastric 
      bypass (OAGB) cause similar improvement of the renal function and reduction of 
      urinary MCP-1 level.
CI  - (c) 2024. The Author(s).
FAU - Elmamlook, Shimaa Monir
AU  - Elmamlook SM
AD  - Ministry of Health, Aga Central Hospital, Aga, Egypt.
FAU - Sabry, Alaa Abd El-Aziz
AU  - Sabry AAE
AD  - Faculty of Medicine, Mansoura University, Jeehan Street, Mansoura, Dakahlia, 
      Egypt.
FAU - Elrefai, Mohamad
AU  - Elrefai M
AUID- ORCID: 0000-0001-9785-9302
AD  - Gastrointestinal Surgical Center, Department of Surgery, Faculty of Medicine, 
      Mansoura University, Mansoura, Egypt. mohelrefai@mans.edu.eg.
AD  - Clinical Sciences Department, Fakeeh College for Medical Sciences, Jeddah, Saudi 
      Arabia. mohelrefai@mans.edu.eg.
FAU - Eldeen, Ahmed Bahie
AU  - Eldeen AB
AD  - Faculty of Medicine, Mansoura University, Jeehan Street, Mansoura, Dakahlia, 
      Egypt.
LA  - eng
PT  - Journal Article
DEP - 20240109
PL  - United States
TA  - Obes Surg
JT  - Obesity surgery
JID - 9106714
RN  - 0 (Chemokine CCL2)
SB  - IM
MH  - Humans
MH  - *Gastric Bypass/methods
MH  - *Obesity, Morbid/surgery
MH  - Prospective Studies
MH  - Quality of Life
MH  - Chemokine CCL2
MH  - Treatment Outcome
MH  - Gastrectomy/methods
MH  - Kidney
MH  - Retrospective Studies
MH  - *Laparoscopy/methods
PMC - PMC10810916
OTO - NOTNLM
OT  - Bariatric Surgery
OT  - Renal Function
OT  - Urinary MCP-1
COIS- The authors declare no competing interests.
EDAT- 2024/01/10 06:42
MHDA- 2024/01/26 06:43
PMCR- 2024/01/09
CRDT- 2024/01/10 00:11
PHST- 2023/05/23 00:00 [received]
PHST- 2023/12/26 00:00 [accepted]
PHST- 2023/11/07 00:00 [revised]
PHST- 2024/01/26 06:43 [medline]
PHST- 2024/01/10 06:42 [pubmed]
PHST- 2024/01/10 00:11 [entrez]
PHST- 2024/01/09 00:00 [pmc-release]
AID - 10.1007/s11695-023-07033-z [pii]
AID - 7033 [pii]
AID - 10.1007/s11695-023-07033-z [doi]
PST - ppublish
SO  - Obes Surg. 2024 Feb;34(2):610-617. doi: 10.1007/s11695-023-07033-z. Epub 2024 Jan 
      9.