PMID- 38196927
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20240111
IS  - 2397-5776 (Electronic)
IS  - 2397-5776 (Linking)
VI  - 9
IP  - Suppl 1
DP  - 2024
TI  - Emergency preparedness for mass casualty events: South Texas commentary on the 
      development of a statewide emergency response system.
PG  - e001150
LID - 10.1136/tsaco-2023-001150 [doi]
LID - e001150
AB  - Mass casualty incidents (MCIs) are on the rise in the USA, and hemorrhage is the 
      leading cause of preventable death in trauma. The need for rapid access to 
      life-saving blood and blood products is essential for preventing death due to 
      hemorrhage. It is well established that most major cities in the USA are 
      underprepared to meet blood transfusion requirements in the event of an MCI. The 
      South Texas Whole Blood Consortium sought to rectify this and vowed to be 
      prepared to provide low-titer type O-positive whole blood (LTOWB) and blood 
      components to the people who need it, where and when they need it. This system 
      was able to transport 25 units of LTOWB and packed red blood cells almost 100 
      miles away to Uvalde Memorial Hospital within just 67 minutes after notification 
      of an active shooter. The regional consortium has created a pool of dedicated 
      LTOWB donors affectionately called Heroes in Arms who can be called on to 
      instantly augment locoregional blood supply. Previously pregnant women have 
      historically been excluded from donating plasma and LTOWB due to the increased 
      rates of human leukocyte antigen (HLA) antibody (Ab) positivity, which is 
      associated with transfusion-related acute lung injury. However, the South Texas 
      Blood and Tissue Center in San Antonio had a large number of qualified, 
      previously pregnant females desire to join the Heroes in Arms program prompting 
      them to assess the feasibility of providing HLA Ab testing for this demographic 
      and the results were promising. This is the first report of previously pregnant 
      women being included in the pool for donation of LTOWB.
CI  - (c) Author(s) (or their employer(s)) 2024. Re-use permitted under CC BY-NC. No 
      commercial re-use. See rights and permissions. Published by BMJ.
FAU - Harrell, Kelly
AU  - Harrell K
AD  - Surgery, UT Health San Antonio, San Antonio, Texas, USA.
FAU - Cirone, Justin
AU  - Cirone J
AD  - Surgery, UT Health San Antonio, San Antonio, Texas, USA.
FAU - Hill, Alexandra
AU  - Hill A
AD  - Surgery, UT Health San Antonio, San Antonio, Texas, USA.
FAU - Johnson, Abigail
AU  - Johnson A
AD  - UT Health San Antonio, San Antonio, Texas, USA.
FAU - McClary, Caleb
AU  - McClary C
AD  - Surgery, UT Health San Antonio, San Antonio, Texas, USA.
FAU - Myers, John C
AU  - Myers JC
AD  - Surgery, UT Health San Antonio, San Antonio, Texas, USA.
FAU - Ngamsuntikul, Samantha
AU  - Ngamsuntikul S
AD  - South Texas Blood and Tissue Center, San Antonio, Texas, USA.
FAU - Mendoza, Adriene
AU  - Mendoza A
AD  - South Texas Blood and Tissue Center, San Antonio, Texas, USA.
FAU - Quesada, Jose
AU  - Quesada J
AUID- ORCID: 0009-0001-8305-2169
AD  - South Texas Blood and Tissue Center, San Antonio, Texas, USA.
FAU - Epley, Eric
AU  - Epley E
AD  - Southwest Texas Regional Advisory Council, San Antonio, Texas, USA.
FAU - Eastridge, Brian
AU  - Eastridge B
AD  - Surgery, UT Health San Antonio, San Antonio, Texas, USA.
FAU - Nicholson, Susannah
AU  - Nicholson S
AD  - Surgery, UT Health San Antonio, San Antonio, Texas, USA.
FAU - Brigmon, Erika P
AU  - Brigmon EP
AUID- ORCID: 0000-0001-7690-6333
AD  - Surgery, UT Health San Antonio, San Antonio, Texas, USA.
FAU - Jenkins, Donald H
AU  - Jenkins DH
AD  - Surgery, UT Health San Antonio, San Antonio, Texas, USA.
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20240105
PL  - England
TA  - Trauma Surg Acute Care Open
JT  - Trauma surgery & acute care open
JID - 101698646
PMC - PMC10773433
OTO - NOTNLM
OT  - Disasters
OT  - Multiple Trauma
OT  - blood transfusion
OT  - death
COIS- Competing interests: None declared.
EDAT- 2024/01/10 06:42
MHDA- 2024/01/10 06:43
PMCR- 2024/01/05
CRDT- 2024/01/10 03:46
PHST- 2023/05/09 00:00 [received]
PHST- 2023/09/16 00:00 [accepted]
PHST- 2024/01/10 06:43 [medline]
PHST- 2024/01/10 06:42 [pubmed]
PHST- 2024/01/10 03:46 [entrez]
PHST- 2024/01/05 00:00 [pmc-release]
AID - tsaco-2023-001150 [pii]
AID - 10.1136/tsaco-2023-001150 [doi]
PST - epublish
SO  - Trauma Surg Acute Care Open. 2024 Jan 5;9(Suppl 1):e001150. doi: 
      10.1136/tsaco-2023-001150. eCollection 2024.