PMID- 38201360
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20240127
IS  - 2075-4418 (Print)
IS  - 2075-4418 (Electronic)
IS  - 2075-4418 (Linking)
VI  - 14
IP  - 1
DP  - 2023 Dec 26
TI  - A Modified Corona Score Using Lung Ultrasound to Identify COVID-19 Patients.
LID - 10.3390/diagnostics14010051 [doi]
LID - 51
AB  - BACKGROUND: COVID-19 continues to circulate around the world with multiple 
      different strains being active at once. While diagnosis with antigen and 
      molecular testing is more readily available, there is still room for alternative 
      methods of diagnosis, particularly in out-of-hospital settings, e.g., home or 
      nursing homes, and in low-medium income countries, where testing may not be 
      readily available. STUDY OBJECTIVES: To evaluate the performance of two modified 
      corona score methods compared with a traditional corona score approach to 
      identify patients with COVID-19. METHODS: This was a retrospective multicenter 
      study performed to compare the ability to predict SARS-CoV-2 test results on a 
      nasopharyngeal swab between the corona scores and two novel corona scores 
      (modified 1 corona score (M1CS) and modified 2 corona score (M2CS)). The M1CS 
      included lung ultrasound (LUS) and chest X-ray (CXR) results, while the M2SC only 
      utilized LUS findings without CXRs. Emergency physicians performed point-of-care 
      LUS and a physical examination upon admission to the emergency department. 
      RESULTS: Subjects positive for SARS-CoV-2 were older and had higher ferritin 
      levels and temperature and lower diastolic blood pressure and oxygen saturation. 
      The two groups differed on corona score and modified corona scores (p < 0.001 for 
      all). SARS-CoV-2-positive patients had fewer pleural line irregularities (p = 
      0.025) but presented more frequently with an interstitial pattern on CXRs (p < 
      0.001). CONCLUSIONS: In our study, LUS alone provided a valuable contribution to 
      the corona score and improved its performance more than when CXR results were 
      included. These results suggest that resource-limited areas where CXRs may be 
      unavailable or prohibitively expensive can utilize an ultrasound as the sole 
      imaging modality without a loss of diagnostic performance for SARS-CoV-2 
      pneumonia diagnosis.
FAU - Caroselli, Costantino
AU  - Caroselli C
AD  - Acute Geriatric Unit, Geriatric Emergency Room and Aging Research Centre IRCCS 
      INRCA, 60127 Ancona, Italy.
FAU - Blaivas, Michael
AU  - Blaivas M
AD  - Department of Medicine, School of Medicine, University of South Carolina, 
      Columbia, SC 29209, USA.
FAU - Tung Chen, Yale
AU  - Tung Chen Y
AUID- ORCID: 0000-0002-5613-3609
AD  - Internal Medicine Department, Hospital Universitario Puerta de Hierro, 28222 
      Majadahonda, Spain.
FAU - Marcosignori, Matteo
AU  - Marcosignori M
AUID- ORCID: 0009-0007-9548-9193
AD  - Emergency Department, Azienda Ospedaliero Universitaria, Ospedali Riuniti, 60123 
      Ancona, Italy.
FAU - Cherubini, Antonio
AU  - Cherubini A
AD  - Acute Geriatric Unit, Geriatric Emergency Room and Aging Research Centre IRCCS 
      INRCA, 60127 Ancona, Italy.
FAU - Longo, Daniele
AU  - Longo D
AUID- ORCID: 0000-0003-4974-2120
AD  - Department of Prevention, APSS, 38123 Trento, Italy.
AD  - Department of Diagnostics and Public Health, School of Medicine and Surgery, 
      Universita di Verona, 37124 Verona, Italy.
LA  - eng
PT  - Journal Article
DEP - 20231226
PL  - Switzerland
TA  - Diagnostics (Basel)
JT  - Diagnostics (Basel, Switzerland)
JID - 101658402
PMC - PMC10804308
OTO - NOTNLM
OT  - COVID-19
OT  - SARS-CoV-2
OT  - corona score
OT  - lung ultrasound
OT  - point of care
COIS- The authors declare that they have no conflicts of interest related to the 
      publication of this manuscript.
EDAT- 2024/01/11 07:41
MHDA- 2024/01/11 07:42
PMCR- 2023/12/26
CRDT- 2024/01/11 01:05
PHST- 2023/10/22 00:00 [received]
PHST- 2023/12/11 00:00 [revised]
PHST- 2023/12/21 00:00 [accepted]
PHST- 2024/01/11 07:42 [medline]
PHST- 2024/01/11 07:41 [pubmed]
PHST- 2024/01/11 01:05 [entrez]
PHST- 2023/12/26 00:00 [pmc-release]
AID - diagnostics14010051 [pii]
AID - diagnostics-14-00051 [pii]
AID - 10.3390/diagnostics14010051 [doi]
PST - epublish
SO  - Diagnostics (Basel). 2023 Dec 26;14(1):51. doi: 10.3390/diagnostics14010051.