PMID- 38213069
OWN - NLM
STAT- MEDLINE
DCOM- 20240418
LR  - 20240418
IS  - 1550-9613 (Electronic)
IS  - 0278-4297 (Linking)
VI  - 43
IP  - 5
DP  - 2024 May
TI  - Do Maternal Heart Diseases Affect Fetal Cardiac Functions?
PG  - 851-861
LID - 10.1002/jum.16414 [doi]
AB  - OBJECTIVES: To investigate whether fetal cardiac function is affected by 
      underlying heart disease in pregnant women. METHODS: A total of 100 pregnant 
      women who were >/=34 gestational weeks were included in the study, 40 in the 
      maternal heart disease (MHD) group diagnosed with heart disease and 60 in the 
      control group. All cardiac diseases in pregnant women were diagnosed 
      preconceptionally and categorized according to the New York Heart Association 
      (NYHA) classification system. Fetal cardiac functions of study groups were 
      evaluated by M-mode, color tissue Doppler imaging (c-TDI), and pulsed wave 
      Doppler. RESULTS: Tricuspid annular plane systolic excursion and myocardial 
      performance index (MPI) values were significantly higher and isovolumetric 
      relaxation time was prolonged in the MHD group. The MPI value was found higher in 
      MHD group with NYHA Class II compared to those with NYHA Class I. No significant 
      change in any of the fetal tricuspid annular peak velocity values measured by 
      c-TDI in the MHD group. There were no differences in fetal cardiac functions and 
      perinatal outcomes between pregnant women with acquired and congenital heart 
      diseases. Patients in NYHA Class II had lower birth weight, 1st and 5th minute 
      APGAR scores, and higher neonatal intensive care unit admission rates. 
      CONCLUSIONS: Underlying heart diseases in pregnant women can cause alterations in 
      the systolic and diastolic function of the fetal heart. High fetal MPI values 
      detected in cardiac patients may indicate that cardiac pathologies during 
      pregnancy affect fetal cardiac globular myocardial function. Cardiac pathologies 
      that progress with restricted physical activity may cause changes in fetal 
      cardiac function and may be associated with adverse perinatal outcomes.
CI  - (c) 2024 American Institute of Ultrasound in Medicine.
FAU - Okutucu, Gulcan
AU  - Okutucu G
AUID- ORCID: 0000-0003-4618-8312
AD  - Department of Obstetrics and Gynecology, Division of Perinatology, Turkish 
      Ministry of Health Ankara City Hospital, Ankara, Turkey.
FAU - Oluklu, Deniz
AU  - Oluklu D
AUID- ORCID: 0000-0002-9050-2041
AD  - Department of Obstetrics and Gynecology, Division of Perinatology, Turkish 
      Ministry of Health Ankara City Hospital, Ankara, Turkey.
FAU - Gulen Yildiz, Esra
AU  - Gulen Yildiz E
AD  - Department of Obstetrics and Gynecology, Division of Perinatology, Turkish 
      Ministry of Health Ankara City Hospital, Ankara, Turkey.
FAU - Bastemur, Ayse Gulcin
AU  - Bastemur AG
AD  - Department of Obstetrics and Gynecology, Division of Perinatology, Turkish 
      Ministry of Health Ankara City Hospital, Ankara, Turkey.
FAU - Tanacan, Atakan
AU  - Tanacan A
AUID- ORCID: 0000-0001-8209-8248
AD  - Department of Obstetrics and Gynecology, Division of Perinatology, University of 
      Health Sciences, Turkish Ministry of Health Ankara City Hospital, Ankara, Turkey.
FAU - Kara, Ozgur
AU  - Kara O
AD  - Department of Obstetrics and Gynecology, Division of Perinatology, University of 
      Health Sciences, Turkish Ministry of Health Ankara City Hospital, Ankara, Turkey.
FAU - Sahin, Dilek
AU  - Sahin D
AD  - Department of Obstetrics and Gynecology, Division of Perinatology, University of 
      Health Sciences, Turkish Ministry of Health Ankara City Hospital, Ankara, Turkey.
LA  - eng
PT  - Journal Article
DEP - 20240111
PL  - England
TA  - J Ultrasound Med
JT  - Journal of ultrasound in medicine : official journal of the American Institute of 
      Ultrasound in Medicine
JID - 8211547
SB  - IM
MH  - Infant, Newborn
MH  - Humans
MH  - Pregnancy
MH  - Female
MH  - *Heart Diseases/complications/diagnostic imaging
MH  - Fetal Heart/diagnostic imaging
MH  - Systole
MH  - Prospective Studies
MH  - Diastole
MH  - Ultrasonography, Prenatal/methods
OTO - NOTNLM
OT  - fetal cardiac functions
OT  - fetal echocardiography
OT  - maternal heart diseases
OT  - myocardial performance index
OT  - pregnancy
EDAT- 2024/01/12 06:43
MHDA- 2024/04/18 06:44
CRDT- 2024/01/12 02:18
PHST- 2023/12/20 00:00 [revised]
PHST- 2023/11/15 00:00 [received]
PHST- 2024/01/01 00:00 [accepted]
PHST- 2024/04/18 06:44 [medline]
PHST- 2024/01/12 06:43 [pubmed]
PHST- 2024/01/12 02:18 [entrez]
AID - 10.1002/jum.16414 [doi]
PST - ppublish
SO  - J Ultrasound Med. 2024 May;43(5):851-861. doi: 10.1002/jum.16414. Epub 2024 Jan 
      11.