PMID- 38213859
OWN - NLM
STAT- MEDLINE
DCOM- 20240115
LR  - 20240115
IS  - 1555-1377 (Electronic)
IS  - 1541-5457 (Print)
IS  - 1541-5457 (Linking)
VI  - 43
IP  - 2
DP  - 2023 Dec
TI  - Sex Differences in Patient-Reported Outcomes Following Surgical Hip Preservation 
      Interventions: A Systematic Review and Meta-Analysis.
PG  - 133-145
AB  - BACKGROUND: Female patients undergoing hip preservation surgery often have 
      inferior patient-reported outcome scores (PROs), raising concerns about the 
      clinical benefit of hip preservation surgery in women. Comparison of preoperative 
      and postoperative PROs, and change in PROs, for female versus (vs.) male hip 
      preservation patients was completed via systematic review. METHODS: In accordance 
      with PRISMA guidelines, the MEDLINE, Cochrane Central, and Em-base databases were 
      searched. Level I-IV studies of patients undergoing surgical intervention for 
      femoroacetabular impingement (FAI) and/or developmental dysplasia of the hip 
      (DDH) with at least two years of postoperative follow-up were included. 
      Sex-stratified PRO scores or outcome information had to be included. RESULTS: We 
      identified 32 hip preservation studies evaluating sex-related PRO differences, 
      and/or providing sex-specific PRO data. The quantitative analysis of 24 studies 
      (1843 patients) was stratified by DDH status. The modified Harris Hip Score 
      (mHHS), Hip Outcome Score-Activities of Daily Living subscale (HOS-ADL), and Hip 
      Outcome Score-Sport-Specific subscale (HOS-SSS) were assessed. Patients 
      undergoing surgery for FAI only were 52.1% female (n= 806/1546). As predicted, 
      women had lower preoperative PRO scores, however, they had significantly greater 
      improvements in HOS-ADL (20.14+/-4.41 vs. 26.00+/-0.35, p<0.05) and HOS-SSS (33.21+/- 
      0.71 vs. 38.33+/- 0.46, p<0.05) compared to males. Similar results were found in 
      the DDH cohort of 330 patients (72.1% female): females had lower preoperative PRO 
      scores, but significantly greater improvement of mHHS (22.68+/-0.45 vs. 10.60+/-1.46, 
      p<0.01). CONCLUSION: The present review suggests that men undergoing surgery for 
      FAI and/or DDH tend to have higher preoperative and postoperative PRO scores. 
      However, it appears that women often have greater preoperative to postoperative 
      improvement in PRO scores. This finding is strongest in surgical treatment of 
      DDH. Level of Evidence: III.
CI  - Copyright (c) The Iowa Orthopaedic Journal 2023.
FAU - Parker, Emily A
AU  - Parker EA
AD  - Department of Orthopedics and Rehabilitation, University of Iowa Hospitals and 
      Clinics, Iowa City, Iowa, USA.
FAU - Peoples, Rebecca
AU  - Peoples R
AD  - Department of Orthopedics and Rehabilitation, University of Iowa Hospitals and 
      Clinics, Iowa City, Iowa, USA.
FAU - Willey, Michael C
AU  - Willey MC
AD  - Department of Orthopedics and Rehabilitation, University of Iowa Hospitals and 
      Clinics, Iowa City, Iowa, USA.
FAU - Westermann, Robert W
AU  - Westermann RW
AD  - Department of Orthopedics and Rehabilitation, University of Iowa Hospitals and 
      Clinics, Iowa City, Iowa, USA.
LA  - eng
PT  - Journal Article
PT  - Meta-Analysis
PT  - Systematic Review
PL  - United States
TA  - Iowa Orthop J
JT  - The Iowa orthopaedic journal
JID - 8908272
SB  - IM
MH  - Humans
MH  - Male
MH  - Female
MH  - *Hip Joint/surgery
MH  - Treatment Outcome
MH  - Activities of Daily Living
MH  - Sex Characteristics
MH  - Arthroscopy/methods
MH  - *Femoracetabular Impingement/surgery
MH  - Patient Reported Outcome Measures
MH  - Follow-Up Studies
MH  - Retrospective Studies
PMC - PMC10777693
OTO - NOTNLM
OT  - clinical assessment/grading scales
OT  - femoroacetabular impingement syndrome
OT  - hip arthroscopy
OT  - hip labral tears
OT  - medical aspects of sports
OT  - patient-reported outcome scores
OT  - patient-reported outcomes
OT  - sex-based physiologic differences
COIS- Disclosures: EAP and RP declare no competing interests. MCW reports personal fees 
      from Dupuy Synthes Sales Inc, other from Smith and Nephew, personal fees from 
      Zimmer Biomet Inc, personal fees from Stryker Corp, outside the submitted work. 
      RWW reports personal fees, non-financial support, and other from Smith & Nephew, 
      other from Arthrex, other from Wardlow Enterprises, personal fees from Medical 
      Device Business Systems, personal fees from Linvatec Corp, outside the submitted 
      work.
EDAT- 2024/01/12 06:42
MHDA- 2024/01/15 12:43
PMCR- 2023/12/01
CRDT- 2024/01/12 03:48
PHST- 2024/01/15 12:43 [medline]
PHST- 2024/01/12 06:42 [pubmed]
PHST- 2024/01/12 03:48 [entrez]
PHST- 2023/12/01 00:00 [pmc-release]
PST - ppublish
SO  - Iowa Orthop J. 2023 Dec;43(2):133-145.