PMID- 38217493
OWN - NLM
STAT- MEDLINE
DCOM- 20240131
LR  - 20240220
IS  - 1520-6882 (Electronic)
IS  - 0003-2700 (Linking)
VI  - 96
IP  - 4
DP  - 2024 Jan 30
TI  - Fluorescent Selectivity-Enhanced FRET Based on 3D Photonic Crystals for 
      Multianalyte Sensing.
PG  - 1630-1639
LID - 10.1021/acs.analchem.3c04547 [doi]
AB  - Fluorescence resonance energy transfer (FRET) finds widespread utility in 
      biochemical sensing, single-molecule experiments, cell physiology, and various 
      other domains due to its inherent simplicity and high sensitivity. Nevertheless, 
      the efficiency of energy transfer between the FRET donor and acceptor is 
      significantly contingent on the local photonic environment, a factor that limits 
      its application in complex systems or multianalyte detections. Here, a 
      fluorescent selectivity-enhanced acridine orange (AO)-aflatoxins (AFs) FRET 
      system based on a range of 3D topological photonic crystals (PCs) was developed 
      with the aim of enhancing the selectivity and discrimination capabilities of 
      FRET. By exploring the angle-dependent characteristics of the photonic stopband, 
      the stopband distribution across different 3D topological PCs pixels was 
      investigated. This approach led to selective fluorescence enhancement in PCs that 
      matched the stopbands, enabling the successful discrimination of six distinct 
      aflatoxins and facilitating complex multianalysis of moldy food samples. In 
      particular, the stopband, which was strategically positioned within the 
      blue-purple structural color range, exhibited a strong alignment with the 
      fluorescence peaks of both the FRET donor and acceptor. This alignment allowed 
      the 3D three-pointed star PCs to be effectively employed for the identification 
      of mixed samples containing six distinct aflatoxins as well as the detection of 
      real aflatoxin samples present in moldy potatoes, bread, oats, and peanuts. 
      Impressively, this approach achieved a remarkable accuracy rate of 100%. This 
      innovative strategy not only presents a novel avenue for developing a multitarget 
      discrimination analysis system but also offers a convenient pretreatment method 
      for the quantitative detection of various aflatoxins.
FAU - Wang, Yanyan
AU  - Wang Y
AD  - State Key Laboratory of Biogeology and Environmental Geology, Faculty of 
      Materials Science and Chemistry, China University of Geosciences, Wuhan 430078, 
      China.
FAU - Luo, Cihui
AU  - Luo C
AD  - State Key Laboratory of Biogeology and Environmental Geology, Faculty of 
      Materials Science and Chemistry, China University of Geosciences, Wuhan 430078, 
      China.
FAU - Lou, Xiaoding
AU  - Lou X
AUID- ORCID: 0000-0002-6556-2034
AD  - State Key Laboratory of Biogeology and Environmental Geology, Faculty of 
      Materials Science and Chemistry, China University of Geosciences, Wuhan 430078, 
      China.
FAU - Li, Fengyu
AU  - Li F
AUID- ORCID: 0000-0003-2481-6111
AD  - College of Chemistry and Materials Science, Guangdong Provincial Key Laboratory 
      of Functional Supramolecular Coordination Materials and Applications, Guangdong 
      Engineering & Technology Research Centre of Graphene-like Materials and Products, 
      Jinan University, Guangzhou 510632, China.
FAU - Huang, Yu
AU  - Huang Y
AUID- ORCID: 0000-0001-9981-2823
AD  - State Key Laboratory of Biogeology and Environmental Geology, Faculty of 
      Materials Science and Chemistry, China University of Geosciences, Wuhan 430078, 
      China.
FAU - Xia, Fan
AU  - Xia F
AUID- ORCID: 0000-0001-7705-4638
AD  - State Key Laboratory of Biogeology and Environmental Geology, Faculty of 
      Materials Science and Chemistry, China University of Geosciences, Wuhan 430078, 
      China.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20240113
PL  - United States
TA  - Anal Chem
JT  - Analytical chemistry
JID - 0370536
RN  - 0 (Coloring Agents)
RN  - 0 (Aflatoxins)
RN  - 0 (Fluorescent Dyes)
SB  - IM
MH  - *Fluorescence Resonance Energy Transfer/methods
MH  - Coloring Agents
MH  - Spectrometry, Fluorescence/methods
MH  - *Aflatoxins
MH  - Fluorescent Dyes/chemistry
EDAT- 2024/01/13 17:43
MHDA- 2024/01/31 06:42
CRDT- 2024/01/13 09:02
PHST- 2024/01/31 06:42 [medline]
PHST- 2024/01/13 17:43 [pubmed]
PHST- 2024/01/13 09:02 [entrez]
AID - 10.1021/acs.analchem.3c04547 [doi]
PST - ppublish
SO  - Anal Chem. 2024 Jan 30;96(4):1630-1639. doi: 10.1021/acs.analchem.3c04547. Epub 
      2024 Jan 13.