PMID- 38221830
OWN - NLM
STAT- MEDLINE
DCOM- 20240116
LR  - 20240329
IS  - 1308-4488 (Electronic)
IS  - 1016-5169 (Linking)
VI  - 52
IP  - 1
DP  - 2024 Jan
TI  - Mitral-Tricuspid Regurgitation Change After Transcatheter Aortic Valve 
      Implantation and Its Effect on Mortality and Hospitalization.
PG  - 10-17
LID - 10.5543/tkda.2023.08130 [doi]
AB  - OBJECTIVE: Moderate to severe mitral regurgitation (MR) and tricuspid 
      regurgitation (TR) are present in approximately 20-60% of patients undergoing 
      transcatheter aortic valve implantation (TAVI). This study aims to evaluate the 
      impact of TAVI on MR and TR, pulmonary hypertension, and reverse cardiac 
      remodeling in these patients.  Methods: Out of 240 patients who underwent TAVI, 
      79 who met the inclusion and exclusion criteria were analyzed. RESULTS: In our 
      study, 46.8% (n = 37) of the patients were male. Nineteen (24.1%) patients died 
      within two years. Before TAVI, 34 (43%) patients had moderate-to-severe MR, which 
      decreased to 18 (22.7%) after the procedure (P < 0.05). Similarly, the number of 
      patients with moderate-to-severe TR decreased from 26 (32.9%) before TAVI to 12 
      (15%) after the procedure (P < 0.05). Of the patients, 50.6% (n = 40) did not 
      require hospitalization after the procedure, while 25 were hospitalized once, 12 
      twice, and 2 three times. The mean systolic pulmonary artery pressure (sPAP) 
      values of the patients decreased from 44.30 +/- 14.42 mmHg before the procedure to 
      39.09 +/- 11.77 mmHg after the procedure (Z=-3.506, P < 0.001). No correlation was 
      found between changes in MR and TR grades after TAVI and mortality or 
      hospitalization during follow-up. Furthermore, there was no statistically 
      significant difference in tricuspid annular plane systolic excursion (TAPSE), 
      free wall annular S' velocity, left atrial volume (LAV), or LAV index (LAVI) 
      before and after TAVI.  Conclusion: There was a significant decrease in 
      moderate-to-severe MR and TR after TAVI; however, this did not impact 
      hospitalization or mortality rates. Additionally, no significant differences were 
      observed in right ventricular systolic function or in LAV and LAVI before and 
      after TAVI.
FAU - Adigozelzade, Samir
AU  - Adigozelzade S
AD  - Central Military Hospital of Ministry Defence of Azerbaijan, Baku, Azerbaijan.
FAU - Asil, Serkan
AU  - Asil S
AD  - Department of Cardiology, Gulhane Training and Research Hospital, Ankara, 
      Turkiye.
FAU - Keskin, Omer Faruk
AU  - Keskin OF
AD  - Department of Cardiology, Gulhane Training and Research Hospital, Ankara, 
      Turkiye.
FAU - Erdogan, Siddik
AU  - Erdogan S
AD  - Department of Cardiology, Istanbul Sile City Hospital, Istanbul, Turkiye.
FAU - Gormel, Suat
AU  - Gormel S
AD  - Department of Cardiology, Gulhane Training and Research Hospital, Ankara, 
      Turkiye.
FAU - Yasar, Salim
AU  - Yasar S
AD  - Department of Cardiology, Gulhane Training and Research Hospital, Ankara, 
      Turkiye.
FAU - Firtina, Serdar
AU  - Firtina S
AD  - Department of Cardiology, Gulhane Training and Research Hospital, Ankara, 
      Turkiye.
FAU - Yildirim, Erkan
AU  - Yildirim E
AD  - Department of Cardiology, Gulhane Training and Research Hospital, Ankara, 
      Turkiye.
FAU - Bugan, Baris
AU  - Bugan B
AD  - Department of Cardiology, Gulhane Training and Research Hospital, Ankara, 
      Turkiye.
FAU - Celik, Murat
AU  - Celik M
AD  - Department of Cardiology, Gulhane Training and Research Hospital, Ankara, 
      Turkiye.
FAU - Barcin, Cem
AU  - Barcin C
AD  - Central Military Hospital of Ministry Defence of Azerbaijan, Baku, Azerbaijan.
FAU - Yuksel, Uygar Cagdas
AU  - Yuksel UC
AD  - Department of Cardiology, Gulhane Training and Research Hospital, Ankara, 
      Turkiye.
LA  - eng
PT  - Journal Article
TT  - Transkateter Aort Kapagi Implantasyonu Sonrasi Mitral-Trikuspit Yetersizligi 
      Degisimi ve Bunun Mortalite ve Hospitalizasyona Etkisi.
PL  - Turkey
TA  - Turk Kardiyol Dern Ars
JT  - Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir
JID - 9426239
SB  - IM
MH  - Humans
MH  - Male
MH  - Female
MH  - *Transcatheter Aortic Valve Replacement/methods
MH  - *Tricuspid Valve Insufficiency/diagnostic imaging/epidemiology
MH  - *Mitral Valve Insufficiency/epidemiology/surgery
MH  - Treatment Outcome
MH  - *Heart Valve Prosthesis Implantation/adverse effects/methods
MH  - *Aortic Valve Stenosis/surgery
MH  - Aortic Valve/surgery
EDAT- 2024/01/15 06:42
MHDA- 2024/01/16 06:41
CRDT- 2024/01/15 03:06
PHST- 2024/01/16 06:41 [medline]
PHST- 2024/01/15 06:42 [pubmed]
PHST- 2024/01/15 03:06 [entrez]
AID - 10.5543/tkda.2023.08130 [doi]
PST - ppublish
SO  - Turk Kardiyol Dern Ars. 2024 Jan;52(1):10-17. doi: 10.5543/tkda.2023.08130.