PMID- 38229458
OWN - NLM
STAT- MEDLINE
DCOM- 20240118
LR  - 20240118
IS  - 0915-1753 (Print)
IS  - 0915-1753 (Linking)
VI  - 33
IP  - 1
DP  - 2023 Dec 26
TI  - A Japanese Case of COVID-19 Caused by Omicron Strain with Y453F Substitution.
PG  - 19-21
AB  - Frequent mutations of SARS-CoV-2 change the strain more transmissible, leading to 
      the pandemic in worldwide. We detected Y453F substitution on Omicron strain, 
      isolated from a Japanese patient in July 2022. While Y453F substitution was 
      identified B1.1.298 lineage in Netherlands and Denmark in 2020, the substitution 
      has not been reported in Omicron strain especially in Japan. Y453F substitution 
      is associated with higher viral infectivity because it is sited in the 
      receptor-binding domain (RBD), and Y453F substitution contributes to increase 
      binding affinity to angiotensin converting enzyme 2 (ACE2). Additionally, Y453F 
      substitution has been reported to escape human leukocyte antigen (HLA), which is 
      known to recognize non-self-antigens in virus-infected cells as cellular 
      immunity, so it should be closely monitored.
FAU - Yamazaki, Hiroka
AU  - Yamazaki H
AD  - Department of Clinical Laboratory, Kanazawa University Hospital.
FAU - Iwata, Yasunori
AU  - Iwata Y
AD  - Department of Infection Control and Prevention, Kanazawa University Hospital. 
      Department of Nephrology and Laboratory Medicine, Kanazawa University Hospital.
FAU - Maekawa, Akiko
AU  - Maekawa A
AD  - Department of Clinical Laboratory, Kanazawa University Hospital.
FAU - Azuma, Tomoko
AU  - Azuma T
AD  - Department of Clinical Laboratory, Kanazawa University Hospital.
FAU - Shimano, Yui
AU  - Shimano Y
AD  - Department of Clinical Laboratory, Kanazawa University Hospital.
FAU - Yokoyama, Tadafumi
AU  - Yokoyama T
AD  - Department of Pediatrics, Kanazawa University Hospital.
FAU - Nakade, Junya
AU  - Nakade J
AD  - Department of Infection Control and Prevention, Kanazawa University Hospital. 
      Department of Hospital Pharmacy, Kanazawa University Hospital.
FAU - Tanaka, Yasunari
AU  - Tanaka Y
AD  - Department of Infection Control and Prevention, Kanazawa University Hospital. 
      Department of Nursing, Kanazawa University Hospital.
FAU - Nakamura, Yoko
AU  - Nakamura Y
AD  - Department of Infection Control and Prevention, Kanazawa University Hospital. 
      Department of Nursing, Kanazawa University Hospital.
FAU - Takahashi, Yoshinori
AU  - Takahashi Y
AD  - Department of Infection Control and Prevention, Kanazawa University Hospital. 
      Department of Rheumatology, Kanazawa University Hospital.
FAU - Zaimoku, Yoshitaka
AU  - Zaimoku Y
AD  - Department of Infection Control and Prevention, Kanazawa University Hospital. 
      Department of Hematology, Kanazawa University Hospital.
FAU - Oe, Hiroyasu
AU  - Oe H
AD  - Department of Clinical Laboratory, Kanazawa University Hospital.
FAU - Oshima, Megumi
AU  - Oshima M
AD  - Department of Clinical Laboratory, Kanazawa University Hospital. Department of 
      Nephrology and Laboratory Medicine, Kanazawa University Hospital.
FAU - Mori, Mika
AU  - Mori M
AD  - Department of Clinical Laboratory, Kanazawa University Hospital. Department of 
      Cardiology, Kanazawa University Hospital.
FAU - Gabata, Toshifumi
AU  - Gabata T
AD  - Department of Clinical Laboratory, Kanazawa University Hospital. Department of 
      Radiology, Kanazawa University Hospital.
LA  - eng
PT  - Journal Article
PL  - Japan
TA  - Rinsho Biseibutshu Jinsoku Shindan Kenkyukai Shi
JT  - Rinsho Biseibutsu Jinsoku Shindan Kenkyukai shi = JARMAM : Journal of the 
      Association for Rapid Method and Automation in Microbiology
JID - 9419185
RN  - 0 (Histocompatibility Antigens Class II)
SB  - IM
MH  - Humans
MH  - *COVID-19
MH  - SARS-CoV-2
MH  - Japan
MH  - Histocompatibility Antigens Class II
MH  - Immunity, Cellular
EDAT- 2024/01/17 06:43
MHDA- 2024/01/18 06:43
CRDT- 2024/01/17 02:18
PHST- 2024/01/18 06:43 [medline]
PHST- 2024/01/17 06:43 [pubmed]
PHST- 2024/01/17 02:18 [entrez]
PST - ppublish
SO  - Rinsho Biseibutshu Jinsoku Shindan Kenkyukai Shi. 2023 Dec 26;33(1):19-21.