PMID- 38229560
OWN - NLM
STAT- MEDLINE
DCOM- 20240417
LR  - 20240417
IS  - 1423-0410 (Electronic)
IS  - 0042-9007 (Linking)
VI  - 119
IP  - 4
DP  - 2024 Apr
TI  - Development, implementation and impact of an immunoglobulin stewardship programme 
      in Saskatchewan, Canada.
PG  - 335-343
LID - 10.1111/vox.13593 [doi]
AB  - BACKGROUND AND OBJECTIVES: Intravenous immunoglobulin (IVIG) is one of the most 
      costly and limited-supply blood products. Judicious use of this therapy is 
      important to ensure a continued supply is available for patients in need. The 
      Saskatchewan IG Stewardship Program was initiated to monitor and reduce 
      inappropriate IG use. MATERIALS AND METHODS: The Program was developed and 
      implemented through the collaborative efforts of a multidisciplinary, 
      inter-organizational team. Funding was provided from provincial organizations to 
      create new positions within the Program and to support stakeholder engagement 
      throughout the process of implementation. Data were collected from local and 
      national databases regarding the amount of IVIG used and appropriateness of 
      orders based on published criteria. RESULTS: Over 20 months, the Program helped 
      to reduce unnecessary IVIG use from pre-intervention levels by more than 20%. 
      Interventions from nurse navigators alone reduced inappropriate IVIG use by 2.6%. 
      During the 20-month period following Program initiation, more than 4 million CAD 
      less was spent on IVIG compared with the previous 20 months. CONCLUSION: The 
      Saskatchewan IG Stewardship Program has led to more appropriate IVIG use across 
      the province, more effective preservation of this limited healthcare resource, 
      and cost savings that more than cover the cost of administering the Program.
CI  - (c) 2024 The Authors. Vox Sanguinis published by John Wiley & Sons Ltd on behalf of 
      International Society of Blood Transfusion.
FAU - Sarker, Kinsuk
AU  - Sarker K
AD  - Stewardship and Clinical Appropriateness, Saskatchewan Health Authority, 
      Saskatoon, Saskatchewan, Canada.
FAU - Vanstone, Jason R
AU  - Vanstone JR
AUID- ORCID: 0000-0001-8411-2664
AD  - Stewardship and Clinical Appropriateness, Saskatchewan Health Authority, 
      Saskatoon, Saskatchewan, Canada.
FAU - Adigun, Oluwaferanmi
AU  - Adigun O
AD  - Stewardship and Clinical Appropriateness, Saskatchewan Health Authority, 
      Saskatoon, Saskatchewan, Canada.
FAU - Boutilier, Brad
AU  - Boutilier B
AD  - Strategy and Innovation, Saskatchewan Health Authority, Saskatoon, Saskatchewan, 
      Canada.
FAU - Comeau, Jessica
AU  - Comeau J
AD  - Transfusion Safety/Patient Blood Management, Saskatchewan Health Authority, 
      Saskatoon, Saskatchewan, Canada.
FAU - Degelman, Michelle L
AU  - Degelman ML
AD  - Stewardship and Clinical Appropriateness, Saskatchewan Health Authority, 
      Saskatoon, Saskatchewan, Canada.
FAU - Gottselig, Paul
AU  - Gottselig P
AD  - Stewardship and Clinical Appropriateness, Saskatchewan Health Authority, 
      Saskatoon, Saskatchewan, Canada.
FAU - Berry, Warren E
AU  - Berry WE
AD  - Stewardship and Clinical Appropriateness, Saskatchewan Health Authority, 
      Saskatoon, Saskatchewan, Canada.
FAU - Milne, Ardyth
AU  - Milne A
AD  - Rheumatology Consultant, Internal Medicine, Saskatchewan Health Authority, 
      Saskatoon, Saskatchewan, Canada.
FAU - Van Vliet, Paula
AU  - Van Vliet P
AD  - Transfusion Safety/Patient Blood Management, Saskatchewan Health Authority, 
      Saskatoon, Saskatchewan, Canada.
FAU - Harding, Sheila Rutledge
AU  - Harding SR
AD  - Transfusion Medicine Consultant, Laboratory Medicine, Saskatchewan Health 
      Authority, Saskatoon, Saskatchewan, Canada.
LA  - eng
PT  - Journal Article
DEP - 20240117
PL  - England
TA  - Vox Sang
JT  - Vox sanguinis
JID - 0413606
RN  - 0 (Immunoglobulins, Intravenous)
SB  - IM
MH  - Humans
MH  - *Immunoglobulins, Intravenous/therapeutic use
MH  - Saskatchewan
MH  - Infusions, Intravenous
OTO - NOTNLM
OT  - immunoglobulin
OT  - implementation
OT  - programme development
OT  - stewardship
EDAT- 2024/01/17 06:43
MHDA- 2024/04/17 06:42
CRDT- 2024/01/17 03:33
PHST- 2023/12/05 00:00 [revised]
PHST- 2023/09/12 00:00 [received]
PHST- 2024/01/03 00:00 [accepted]
PHST- 2024/04/17 06:42 [medline]
PHST- 2024/01/17 06:43 [pubmed]
PHST- 2024/01/17 03:33 [entrez]
AID - 10.1111/vox.13593 [doi]
PST - ppublish
SO  - Vox Sang. 2024 Apr;119(4):335-343. doi: 10.1111/vox.13593. Epub 2024 Jan 17.