PMID- 38231622
OWN - NLM
STAT- MEDLINE
DCOM- 20240122
LR  - 20240410
IS  - 1533-4406 (Electronic)
IS  - 0028-4793 (Linking)
VI  - 390
IP  - 3
DP  - 2024 Jan 18
TI  - Long-Term Outcomes of Resynchronization-Defibrillation for Heart Failure.
PG  - 212-220
LID - 10.1056/NEJMoa2304542 [doi]
AB  - BACKGROUND: The Resynchronization-Defibrillation for Ambulatory Heart Failure 
      Trial (RAFT) showed a greater benefit with respect to mortality at 5 years among 
      patients who received cardiac-resynchronization therapy (CRT) than among those 
      who received implantable cardioverter-defibrillators (ICDs). However, the effect 
      of CRT on long-term survival is not known. METHODS: We randomly assigned patients 
      with New York Heart Association (NYHA) class II or III heart failure, a left 
      ventricular ejection fraction of 30% or less, and an intrinsic QRS duration of 
      120 msec or more (or a paced QRS duration of 200 msec or more) to receive either 
      an ICD alone or a CRT defibrillator (CRT-D). We assessed long-term outcomes among 
      patients at the eight highest-enrolling participating sites. The primary outcome 
      was death from any cause; the secondary outcome was a composite of death from any 
      cause, heart transplantation, or implantation of a ventricular assist device. 
      RESULTS: The trial enrolled 1798 patients, of whom 1050 were included in the 
      long-term survival trial; the median duration of follow-up for the 1050 patients 
      was 7.7 years (interquartile range, 3.9 to 12.8), and the median duration of 
      follow-up for those who survived was 13.9 years (interquartile range, 12.8 to 
      15.7). Death occurred in 405 of 530 patients (76.4%) assigned to the ICD group 
      and in 370 of 520 patients (71.2%) assigned to the CRT-D group. The time until 
      death appeared to be longer for those assigned to receive a CRT-D than for those 
      assigned to receive an ICD (acceleration factor, 0.80; 95% confidence interval, 
      0.69 to 0.92; P = 0.002). A secondary-outcome event occurred in 412 patients 
      (77.7%) in the ICD group and in 392 (75.4%) in the CRT-D group. CONCLUSIONS: 
      Among patients with a reduced ejection fraction, a widened QRS complex, and NYHA 
      class II or III heart failure, the survival benefit associated with receipt of a 
      CRT-D as compared with ICD appeared to be sustained during a median of nearly 14 
      years of follow-up. (RAFT ClinicalTrials.gov number, NCT00251251.).
CI  - Copyright (c) 2024 Massachusetts Medical Society.
FAU - Sapp, John L
AU  - Sapp JL
AUID- ORCID: 0000-0002-9602-2751
AD  - From QEII Health Sciences Centre, Dalhousie University, Halifax, NS (J.L.S., 
      R.P.), the Mazankowski Alberta Heart Institute, University of Alberta, Edmonton 
      (S.S., S.K.), the University of Ottawa Heart Institute, Ottawa (C.J.R., N.H.N.L., 
      G.W.), Schulich School of Medicine and Dentistry, Western University, London, ON 
      (H.K., J.M., C.E.M., A.S.L.T.), Libin Cardiovascular Institute, Calgary, AB 
      (D.V.E., G.S.), McMaster University, Hamilton, ON (J.S.H.), Montreal Heart 
      Institute, Montreal (B.T., B.M., M.T., J.R.), Royal Jubilee Hospital, Victoria, 
      BC (L.D.S.), and the University of Toronto, Toronto (S.M.) - all in Canada; and 
      King Abdulaziz University, Jeddah, Saudi Arabia (A.M.).
FAU - Sivakumaran, Soori
AU  - Sivakumaran S
AD  - From QEII Health Sciences Centre, Dalhousie University, Halifax, NS (J.L.S., 
      R.P.), the Mazankowski Alberta Heart Institute, University of Alberta, Edmonton 
      (S.S., S.K.), the University of Ottawa Heart Institute, Ottawa (C.J.R., N.H.N.L., 
      G.W.), Schulich School of Medicine and Dentistry, Western University, London, ON 
      (H.K., J.M., C.E.M., A.S.L.T.), Libin Cardiovascular Institute, Calgary, AB 
      (D.V.E., G.S.), McMaster University, Hamilton, ON (J.S.H.), Montreal Heart 
      Institute, Montreal (B.T., B.M., M.T., J.R.), Royal Jubilee Hospital, Victoria, 
      BC (L.D.S.), and the University of Toronto, Toronto (S.M.) - all in Canada; and 
      King Abdulaziz University, Jeddah, Saudi Arabia (A.M.).
FAU - Redpath, Calum J
AU  - Redpath CJ
AD  - From QEII Health Sciences Centre, Dalhousie University, Halifax, NS (J.L.S., 
      R.P.), the Mazankowski Alberta Heart Institute, University of Alberta, Edmonton 
      (S.S., S.K.), the University of Ottawa Heart Institute, Ottawa (C.J.R., N.H.N.L., 
      G.W.), Schulich School of Medicine and Dentistry, Western University, London, ON 
      (H.K., J.M., C.E.M., A.S.L.T.), Libin Cardiovascular Institute, Calgary, AB 
      (D.V.E., G.S.), McMaster University, Hamilton, ON (J.S.H.), Montreal Heart 
      Institute, Montreal (B.T., B.M., M.T., J.R.), Royal Jubilee Hospital, Victoria, 
      BC (L.D.S.), and the University of Toronto, Toronto (S.M.) - all in Canada; and 
      King Abdulaziz University, Jeddah, Saudi Arabia (A.M.).
FAU - Khan, Habib
AU  - Khan H
AD  - From QEII Health Sciences Centre, Dalhousie University, Halifax, NS (J.L.S., 
      R.P.), the Mazankowski Alberta Heart Institute, University of Alberta, Edmonton 
      (S.S., S.K.), the University of Ottawa Heart Institute, Ottawa (C.J.R., N.H.N.L., 
      G.W.), Schulich School of Medicine and Dentistry, Western University, London, ON 
      (H.K., J.M., C.E.M., A.S.L.T.), Libin Cardiovascular Institute, Calgary, AB 
      (D.V.E., G.S.), McMaster University, Hamilton, ON (J.S.H.), Montreal Heart 
      Institute, Montreal (B.T., B.M., M.T., J.R.), Royal Jubilee Hospital, Victoria, 
      BC (L.D.S.), and the University of Toronto, Toronto (S.M.) - all in Canada; and 
      King Abdulaziz University, Jeddah, Saudi Arabia (A.M.).
FAU - Parkash, Ratika
AU  - Parkash R
AD  - From QEII Health Sciences Centre, Dalhousie University, Halifax, NS (J.L.S., 
      R.P.), the Mazankowski Alberta Heart Institute, University of Alberta, Edmonton 
      (S.S., S.K.), the University of Ottawa Heart Institute, Ottawa (C.J.R., N.H.N.L., 
      G.W.), Schulich School of Medicine and Dentistry, Western University, London, ON 
      (H.K., J.M., C.E.M., A.S.L.T.), Libin Cardiovascular Institute, Calgary, AB 
      (D.V.E., G.S.), McMaster University, Hamilton, ON (J.S.H.), Montreal Heart 
      Institute, Montreal (B.T., B.M., M.T., J.R.), Royal Jubilee Hospital, Victoria, 
      BC (L.D.S.), and the University of Toronto, Toronto (S.M.) - all in Canada; and 
      King Abdulaziz University, Jeddah, Saudi Arabia (A.M.).
FAU - Exner, Derek V
AU  - Exner DV
AD  - From QEII Health Sciences Centre, Dalhousie University, Halifax, NS (J.L.S., 
      R.P.), the Mazankowski Alberta Heart Institute, University of Alberta, Edmonton 
      (S.S., S.K.), the University of Ottawa Heart Institute, Ottawa (C.J.R., N.H.N.L., 
      G.W.), Schulich School of Medicine and Dentistry, Western University, London, ON 
      (H.K., J.M., C.E.M., A.S.L.T.), Libin Cardiovascular Institute, Calgary, AB 
      (D.V.E., G.S.), McMaster University, Hamilton, ON (J.S.H.), Montreal Heart 
      Institute, Montreal (B.T., B.M., M.T., J.R.), Royal Jubilee Hospital, Victoria, 
      BC (L.D.S.), and the University of Toronto, Toronto (S.M.) - all in Canada; and 
      King Abdulaziz University, Jeddah, Saudi Arabia (A.M.).
FAU - Healey, Jeff S
AU  - Healey JS
AUID- ORCID: 0000-0003-1216-7580
AD  - From QEII Health Sciences Centre, Dalhousie University, Halifax, NS (J.L.S., 
      R.P.), the Mazankowski Alberta Heart Institute, University of Alberta, Edmonton 
      (S.S., S.K.), the University of Ottawa Heart Institute, Ottawa (C.J.R., N.H.N.L., 
      G.W.), Schulich School of Medicine and Dentistry, Western University, London, ON 
      (H.K., J.M., C.E.M., A.S.L.T.), Libin Cardiovascular Institute, Calgary, AB 
      (D.V.E., G.S.), McMaster University, Hamilton, ON (J.S.H.), Montreal Heart 
      Institute, Montreal (B.T., B.M., M.T., J.R.), Royal Jubilee Hospital, Victoria, 
      BC (L.D.S.), and the University of Toronto, Toronto (S.M.) - all in Canada; and 
      King Abdulaziz University, Jeddah, Saudi Arabia (A.M.).
FAU - Thibault, Bernard
AU  - Thibault B
AD  - From QEII Health Sciences Centre, Dalhousie University, Halifax, NS (J.L.S., 
      R.P.), the Mazankowski Alberta Heart Institute, University of Alberta, Edmonton 
      (S.S., S.K.), the University of Ottawa Heart Institute, Ottawa (C.J.R., N.H.N.L., 
      G.W.), Schulich School of Medicine and Dentistry, Western University, London, ON 
      (H.K., J.M., C.E.M., A.S.L.T.), Libin Cardiovascular Institute, Calgary, AB 
      (D.V.E., G.S.), McMaster University, Hamilton, ON (J.S.H.), Montreal Heart 
      Institute, Montreal (B.T., B.M., M.T., J.R.), Royal Jubilee Hospital, Victoria, 
      BC (L.D.S.), and the University of Toronto, Toronto (S.M.) - all in Canada; and 
      King Abdulaziz University, Jeddah, Saudi Arabia (A.M.).
FAU - Sterns, Laurence D
AU  - Sterns LD
AD  - From QEII Health Sciences Centre, Dalhousie University, Halifax, NS (J.L.S., 
      R.P.), the Mazankowski Alberta Heart Institute, University of Alberta, Edmonton 
      (S.S., S.K.), the University of Ottawa Heart Institute, Ottawa (C.J.R., N.H.N.L., 
      G.W.), Schulich School of Medicine and Dentistry, Western University, London, ON 
      (H.K., J.M., C.E.M., A.S.L.T.), Libin Cardiovascular Institute, Calgary, AB 
      (D.V.E., G.S.), McMaster University, Hamilton, ON (J.S.H.), Montreal Heart 
      Institute, Montreal (B.T., B.M., M.T., J.R.), Royal Jubilee Hospital, Victoria, 
      BC (L.D.S.), and the University of Toronto, Toronto (S.M.) - all in Canada; and 
      King Abdulaziz University, Jeddah, Saudi Arabia (A.M.).
FAU - Lam, Nhat Hung N
AU  - Lam NHN
AD  - From QEII Health Sciences Centre, Dalhousie University, Halifax, NS (J.L.S., 
      R.P.), the Mazankowski Alberta Heart Institute, University of Alberta, Edmonton 
      (S.S., S.K.), the University of Ottawa Heart Institute, Ottawa (C.J.R., N.H.N.L., 
      G.W.), Schulich School of Medicine and Dentistry, Western University, London, ON 
      (H.K., J.M., C.E.M., A.S.L.T.), Libin Cardiovascular Institute, Calgary, AB 
      (D.V.E., G.S.), McMaster University, Hamilton, ON (J.S.H.), Montreal Heart 
      Institute, Montreal (B.T., B.M., M.T., J.R.), Royal Jubilee Hospital, Victoria, 
      BC (L.D.S.), and the University of Toronto, Toronto (S.M.) - all in Canada; and 
      King Abdulaziz University, Jeddah, Saudi Arabia (A.M.).
FAU - Manlucu, Jaimie
AU  - Manlucu J
AD  - From QEII Health Sciences Centre, Dalhousie University, Halifax, NS (J.L.S., 
      R.P.), the Mazankowski Alberta Heart Institute, University of Alberta, Edmonton 
      (S.S., S.K.), the University of Ottawa Heart Institute, Ottawa (C.J.R., N.H.N.L., 
      G.W.), Schulich School of Medicine and Dentistry, Western University, London, ON 
      (H.K., J.M., C.E.M., A.S.L.T.), Libin Cardiovascular Institute, Calgary, AB 
      (D.V.E., G.S.), McMaster University, Hamilton, ON (J.S.H.), Montreal Heart 
      Institute, Montreal (B.T., B.M., M.T., J.R.), Royal Jubilee Hospital, Victoria, 
      BC (L.D.S.), and the University of Toronto, Toronto (S.M.) - all in Canada; and 
      King Abdulaziz University, Jeddah, Saudi Arabia (A.M.).
FAU - Mokhtar, Ahmed
AU  - Mokhtar A
AD  - From QEII Health Sciences Centre, Dalhousie University, Halifax, NS (J.L.S., 
      R.P.), the Mazankowski Alberta Heart Institute, University of Alberta, Edmonton 
      (S.S., S.K.), the University of Ottawa Heart Institute, Ottawa (C.J.R., N.H.N.L., 
      G.W.), Schulich School of Medicine and Dentistry, Western University, London, ON 
      (H.K., J.M., C.E.M., A.S.L.T.), Libin Cardiovascular Institute, Calgary, AB 
      (D.V.E., G.S.), McMaster University, Hamilton, ON (J.S.H.), Montreal Heart 
      Institute, Montreal (B.T., B.M., M.T., J.R.), Royal Jubilee Hospital, Victoria, 
      BC (L.D.S.), and the University of Toronto, Toronto (S.M.) - all in Canada; and 
      King Abdulaziz University, Jeddah, Saudi Arabia (A.M.).
FAU - Sumner, Glen
AU  - Sumner G
AD  - From QEII Health Sciences Centre, Dalhousie University, Halifax, NS (J.L.S., 
      R.P.), the Mazankowski Alberta Heart Institute, University of Alberta, Edmonton 
      (S.S., S.K.), the University of Ottawa Heart Institute, Ottawa (C.J.R., N.H.N.L., 
      G.W.), Schulich School of Medicine and Dentistry, Western University, London, ON 
      (H.K., J.M., C.E.M., A.S.L.T.), Libin Cardiovascular Institute, Calgary, AB 
      (D.V.E., G.S.), McMaster University, Hamilton, ON (J.S.H.), Montreal Heart 
      Institute, Montreal (B.T., B.M., M.T., J.R.), Royal Jubilee Hospital, Victoria, 
      BC (L.D.S.), and the University of Toronto, Toronto (S.M.) - all in Canada; and 
      King Abdulaziz University, Jeddah, Saudi Arabia (A.M.).
FAU - McKinlay, Stuart
AU  - McKinlay S
AD  - From QEII Health Sciences Centre, Dalhousie University, Halifax, NS (J.L.S., 
      R.P.), the Mazankowski Alberta Heart Institute, University of Alberta, Edmonton 
      (S.S., S.K.), the University of Ottawa Heart Institute, Ottawa (C.J.R., N.H.N.L., 
      G.W.), Schulich School of Medicine and Dentistry, Western University, London, ON 
      (H.K., J.M., C.E.M., A.S.L.T.), Libin Cardiovascular Institute, Calgary, AB 
      (D.V.E., G.S.), McMaster University, Hamilton, ON (J.S.H.), Montreal Heart 
      Institute, Montreal (B.T., B.M., M.T., J.R.), Royal Jubilee Hospital, Victoria, 
      BC (L.D.S.), and the University of Toronto, Toronto (S.M.) - all in Canada; and 
      King Abdulaziz University, Jeddah, Saudi Arabia (A.M.).
FAU - Kimber, Shane
AU  - Kimber S
AD  - From QEII Health Sciences Centre, Dalhousie University, Halifax, NS (J.L.S., 
      R.P.), the Mazankowski Alberta Heart Institute, University of Alberta, Edmonton 
      (S.S., S.K.), the University of Ottawa Heart Institute, Ottawa (C.J.R., N.H.N.L., 
      G.W.), Schulich School of Medicine and Dentistry, Western University, London, ON 
      (H.K., J.M., C.E.M., A.S.L.T.), Libin Cardiovascular Institute, Calgary, AB 
      (D.V.E., G.S.), McMaster University, Hamilton, ON (J.S.H.), Montreal Heart 
      Institute, Montreal (B.T., B.M., M.T., J.R.), Royal Jubilee Hospital, Victoria, 
      BC (L.D.S.), and the University of Toronto, Toronto (S.M.) - all in Canada; and 
      King Abdulaziz University, Jeddah, Saudi Arabia (A.M.).
FAU - Mondesert, Blandine
AU  - Mondesert B
AD  - From QEII Health Sciences Centre, Dalhousie University, Halifax, NS (J.L.S., 
      R.P.), the Mazankowski Alberta Heart Institute, University of Alberta, Edmonton 
      (S.S., S.K.), the University of Ottawa Heart Institute, Ottawa (C.J.R., N.H.N.L., 
      G.W.), Schulich School of Medicine and Dentistry, Western University, London, ON 
      (H.K., J.M., C.E.M., A.S.L.T.), Libin Cardiovascular Institute, Calgary, AB 
      (D.V.E., G.S.), McMaster University, Hamilton, ON (J.S.H.), Montreal Heart 
      Institute, Montreal (B.T., B.M., M.T., J.R.), Royal Jubilee Hospital, Victoria, 
      BC (L.D.S.), and the University of Toronto, Toronto (S.M.) - all in Canada; and 
      King Abdulaziz University, Jeddah, Saudi Arabia (A.M.).
FAU - Talajic, Mario
AU  - Talajic M
AD  - From QEII Health Sciences Centre, Dalhousie University, Halifax, NS (J.L.S., 
      R.P.), the Mazankowski Alberta Heart Institute, University of Alberta, Edmonton 
      (S.S., S.K.), the University of Ottawa Heart Institute, Ottawa (C.J.R., N.H.N.L., 
      G.W.), Schulich School of Medicine and Dentistry, Western University, London, ON 
      (H.K., J.M., C.E.M., A.S.L.T.), Libin Cardiovascular Institute, Calgary, AB 
      (D.V.E., G.S.), McMaster University, Hamilton, ON (J.S.H.), Montreal Heart 
      Institute, Montreal (B.T., B.M., M.T., J.R.), Royal Jubilee Hospital, Victoria, 
      BC (L.D.S.), and the University of Toronto, Toronto (S.M.) - all in Canada; and 
      King Abdulaziz University, Jeddah, Saudi Arabia (A.M.).
FAU - Rouleau, Jean
AU  - Rouleau J
AD  - From QEII Health Sciences Centre, Dalhousie University, Halifax, NS (J.L.S., 
      R.P.), the Mazankowski Alberta Heart Institute, University of Alberta, Edmonton 
      (S.S., S.K.), the University of Ottawa Heart Institute, Ottawa (C.J.R., N.H.N.L., 
      G.W.), Schulich School of Medicine and Dentistry, Western University, London, ON 
      (H.K., J.M., C.E.M., A.S.L.T.), Libin Cardiovascular Institute, Calgary, AB 
      (D.V.E., G.S.), McMaster University, Hamilton, ON (J.S.H.), Montreal Heart 
      Institute, Montreal (B.T., B.M., M.T., J.R.), Royal Jubilee Hospital, Victoria, 
      BC (L.D.S.), and the University of Toronto, Toronto (S.M.) - all in Canada; and 
      King Abdulaziz University, Jeddah, Saudi Arabia (A.M.).
FAU - McCarron, C Elizabeth
AU  - McCarron CE
AD  - From QEII Health Sciences Centre, Dalhousie University, Halifax, NS (J.L.S., 
      R.P.), the Mazankowski Alberta Heart Institute, University of Alberta, Edmonton 
      (S.S., S.K.), the University of Ottawa Heart Institute, Ottawa (C.J.R., N.H.N.L., 
      G.W.), Schulich School of Medicine and Dentistry, Western University, London, ON 
      (H.K., J.M., C.E.M., A.S.L.T.), Libin Cardiovascular Institute, Calgary, AB 
      (D.V.E., G.S.), McMaster University, Hamilton, ON (J.S.H.), Montreal Heart 
      Institute, Montreal (B.T., B.M., M.T., J.R.), Royal Jubilee Hospital, Victoria, 
      BC (L.D.S.), and the University of Toronto, Toronto (S.M.) - all in Canada; and 
      King Abdulaziz University, Jeddah, Saudi Arabia (A.M.).
FAU - Wells, George
AU  - Wells G
AD  - From QEII Health Sciences Centre, Dalhousie University, Halifax, NS (J.L.S., 
      R.P.), the Mazankowski Alberta Heart Institute, University of Alberta, Edmonton 
      (S.S., S.K.), the University of Ottawa Heart Institute, Ottawa (C.J.R., N.H.N.L., 
      G.W.), Schulich School of Medicine and Dentistry, Western University, London, ON 
      (H.K., J.M., C.E.M., A.S.L.T.), Libin Cardiovascular Institute, Calgary, AB 
      (D.V.E., G.S.), McMaster University, Hamilton, ON (J.S.H.), Montreal Heart 
      Institute, Montreal (B.T., B.M., M.T., J.R.), Royal Jubilee Hospital, Victoria, 
      BC (L.D.S.), and the University of Toronto, Toronto (S.M.) - all in Canada; and 
      King Abdulaziz University, Jeddah, Saudi Arabia (A.M.).
FAU - Tang, Anthony S L
AU  - Tang ASL
AD  - From QEII Health Sciences Centre, Dalhousie University, Halifax, NS (J.L.S., 
      R.P.), the Mazankowski Alberta Heart Institute, University of Alberta, Edmonton 
      (S.S., S.K.), the University of Ottawa Heart Institute, Ottawa (C.J.R., N.H.N.L., 
      G.W.), Schulich School of Medicine and Dentistry, Western University, London, ON 
      (H.K., J.M., C.E.M., A.S.L.T.), Libin Cardiovascular Institute, Calgary, AB 
      (D.V.E., G.S.), McMaster University, Hamilton, ON (J.S.H.), Montreal Heart 
      Institute, Montreal (B.T., B.M., M.T., J.R.), Royal Jubilee Hospital, Victoria, 
      BC (L.D.S.), and the University of Toronto, Toronto (S.M.) - all in Canada; and 
      King Abdulaziz University, Jeddah, Saudi Arabia (A.M.).
CN  - RAFT Long-Term Study Team
LA  - eng
SI  - ClinicalTrials.gov/NCT00251251
PT  - Comparative Study
PT  - Journal Article
PT  - Multicenter Study
PT  - Randomized Controlled Trial
PL  - United States
TA  - N Engl J Med
JT  - The New England journal of medicine
JID - 0255562
SB  - IM
CIN - N Engl J Med. 2024 Apr 11;390(14):1343-1344. PMID: 38598808
CIN - N Engl J Med. 2024 Apr 11;390(14):1344. PMID: 38598809
CIN - N Engl J Med. 2024 Apr 11;390(14):1343-1345. PMID: 38598810
MH  - Humans
MH  - *Cardiac Resynchronization Therapy
MH  - *Defibrillators, Implantable
MH  - *Heart Failure/mortality/physiopathology/therapy
MH  - Kaplan-Meier Estimate
MH  - Stroke Volume
MH  - Treatment Outcome
MH  - Ventricular Function, Left
MH  - Electrocardiography
MH  - Follow-Up Studies
MH  - Time Factors
FIR - Sapp, John L
IR  - Sapp JL
FIR - Mokhtar, Ahmed
IR  - Mokhtar A
FIR - Parkash, Ratika
IR  - Parkash R
FIR - Giddens, Karen
IR  - Giddens K
FIR - Davis, Aileen
IR  - Davis A
FIR - Healey, Jeff S
IR  - Healey JS
FIR - McKinlay, Stuart
IR  - McKinlay S
FIR - Frechette, Angela
IR  - Frechette A
FIR - Redpath, Calum J
IR  - Redpath CJ
FIR - Thibault, Bernard
IR  - Thibault B
FIR - Mondesert, Blandine
IR  - Mondesert B
FIR - Talajic, Mario
IR  - Talajic M
FIR - Knight, Tammy
IR  - Knight T
FIR - Beaudoin, Sarah
IR  - Beaudoin S
FIR - Girard, Caroline
IR  - Girard C
FIR - Lemarbre, Francois
IR  - Lemarbre F
FIR - Tang, Anthony S L
IR  - Tang ASL
FIR - Khan, Habib
IR  - Khan H
FIR - Manlucu, Jaimie
IR  - Manlucu J
FIR - Exner, Derek V
IR  - Exner DV
FIR - Sumner, Glen
IR  - Sumner G
FIR - Wall, Sabrina
IR  - Wall S
FIR - Zein Abden, Zina
IR  - Zein Abden Z
FIR - Triemstra, Samuel
IR  - Triemstra S
FIR - McKeage, Jennifer
IR  - McKeage J
FIR - Cowan, Karen
IR  - Cowan K
FIR - Sterns, Laurence D
IR  - Sterns LD
FIR - Patterson, Caitlin
IR  - Patterson C
FIR - Gray, Jake
IR  - Gray J
FIR - Sivakumaran, Soori
IR  - Sivakumaran S
FIR - Kimber, Shane
IR  - Kimber S
FIR - Becher, Harald
IR  - Becher H
FIR - Tsuyuki, Ross
IR  - Tsuyuki R
FIR - Lam, Nhat Hung N
IR  - Lam NHN
FIR - Rouleau, Jean
IR  - Rouleau J
FIR - McCarron, C Elizabeth
IR  - McCarron CE
FIR - Wells, George
IR  - Wells G
FIR - Theoret-Patrick, Patricia
IR  - Theoret-Patrick P
FIR - Dhooma, Janel
IR  - Dhooma J
EDAT- 2024/01/17 18:42
MHDA- 2024/01/19 06:42
CRDT- 2024/01/17 12:04
PHST- 2024/01/19 06:42 [medline]
PHST- 2024/01/17 18:42 [pubmed]
PHST- 2024/01/17 12:04 [entrez]
AID - 10.1056/NEJMoa2304542 [doi]
PST - ppublish
SO  - N Engl J Med. 2024 Jan 18;390(3):212-220. doi: 10.1056/NEJMoa2304542.