PMID- 38248258
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20240128
IS  - 2076-3425 (Print)
IS  - 2076-3425 (Electronic)
IS  - 2076-3425 (Linking)
VI  - 14
IP  - 1
DP  - 2023 Dec 31
TI  - Neural Correlates of Positive Outcome Expectancy for Aggression: Evidence from 
      Voxel-Based Morphometry and Resting-State Functional Connectivity Analysis.
LID - 10.3390/brainsci14010043 [doi]
LID - 43
AB  - Positive outcome expectancy is a crucial cognitive factor influencing aggression, 
      yet its neural basis remains unclear. Therefore, the present study combined 
      voxel-based morphometry (VBM) with a resting-state functional connectivity (RSFC) 
      analysis to investigate the brain correlates of positive outcome expectancy in 
      aggression in young people. In the VBM analysis, multiple linear regression was 
      conducted to explore the relationship between individual differences in 
      aggressive positive outcome expectancy and regional gray matter volume (GMV) 
      among 325 undergraduate students. For the RSFC analysis, seed regions were 
      selected based on the results of the VBM analysis. Subsequently, multiple linear 
      regression was employed to examine whether a significant correlation existed 
      between individual differences in aggressive positive outcome expectancy and the 
      RSFC of seed regions with other brain regions in 304 undergraduate students. The 
      findings indicated that aggressive positive outcome expectancy was positively 
      correlated with GMV in the posterior cingulate cortex (PCC), right 
      temporoparietal junction (TPJ), and medial prefrontal cortex (MPFC). Moreover, it 
      was also positively associated with RSFC between the PCC and the left 
      dorsolateral prefrontal cortex (DLPFC). The prediction analysis indicated robust 
      relationships between aggressive positive outcome expectancy and the GMV in the 
      PCC, right TPJ, as well as the RSFC between the PCC and the left DLPFC. Our 
      research provides the initial evidence for the neural basis of positive outcome 
      expectancy in aggression, suggesting the potential role of the PCC as a hub in 
      its neural network.
FAU - Wei, Jia-Ming
AU  - Wei JM
AD  - Research Center of Psychology and Social Development, Faculty of Psychology, 
      Southwest University, Chongqing 400715, China.
AD  - Key Laboratory of Cognition and Personality (Southwest University), Ministry of 
      Education, Chongqing 400715, China.
FAU - Xia, Ling-Xiang
AU  - Xia LX
AUID- ORCID: 0000-0003-4024-5312
AD  - Research Center of Psychology and Social Development, Faculty of Psychology, 
      Southwest University, Chongqing 400715, China.
AD  - Key Laboratory of Cognition and Personality (Southwest University), Ministry of 
      Education, Chongqing 400715, China.
LA  - eng
GR  - 32171071/National Natural Science Foundation of China/
PT  - Journal Article
DEP - 20231231
PL  - Switzerland
TA  - Brain Sci
JT  - Brain sciences
JID - 101598646
PMC - PMC10813425
OTO - NOTNLM
OT  - RSFC
OT  - VBM
OT  - aggression
OT  - medial prefrontal cortex
OT  - positive outcome expectancy
OT  - posterior cingulate cortex
OT  - prediction analysis
OT  - temporoparietal junction
COIS- The authors declare no conflicts of interest.
EDAT- 2024/01/22 06:42
MHDA- 2024/01/22 06:43
PMCR- 2023/12/31
CRDT- 2024/01/22 04:37
PHST- 2023/11/17 00:00 [received]
PHST- 2023/12/23 00:00 [revised]
PHST- 2023/12/29 00:00 [accepted]
PHST- 2024/01/22 06:43 [medline]
PHST- 2024/01/22 06:42 [pubmed]
PHST- 2024/01/22 04:37 [entrez]
PHST- 2023/12/31 00:00 [pmc-release]
AID - brainsci14010043 [pii]
AID - brainsci-14-00043 [pii]
AID - 10.3390/brainsci14010043 [doi]
PST - epublish
SO  - Brain Sci. 2023 Dec 31;14(1):43. doi: 10.3390/brainsci14010043.