PMID- 38250825
OWN - NLM
STAT- MEDLINE
DCOM- 20240208
LR  - 20240208
IS  - 1473-5660 (Electronic)
IS  - 0342-5282 (Linking)
VI  - 47
IP  - 1
DP  - 2024 Mar 1
TI  - Challenges in applying minimal clinically important difference: a critical 
      review.
PG  - 10-19
LID - 10.1097/MRR.0000000000000613 [doi]
AB  - Healthcare clinicians strive to make meaningful changes in patient function and 
      participation. A minimal clinically important difference (MCID) is an estimate of 
      the magnitude of change needed to be meaningful to a patient. Clinicians and 
      investigators may assume that a cited MCID is a valid and generalizable estimate 
      of effect. There are, however, at least two concerns about this assumption. 
      First, multiple methods exist for calculating an MCID that can yield divergent 
      values and raise doubt as to which one to apply. Second, MCID values may be 
      erroneously generalized to patients with dissimilar health conditions. With this 
      in mind, we reviewed the methods used to calculate MCID and citations of reported 
      MCID values for outcome measures commonly used in neurologic, orthopedic, and 
      geriatric populations. Our goal was to assess whether the calculation methods 
      were acknowledged in the cited work and whether the enrolled patients were 
      similar to the sample from which the MCID estimate was derived. We found a 
      concerning variation in the methods employed to estimate MCID. We also found a 
      lack of transparency in identifying calculation methods and applicable health 
      conditions in the cited work. Thus, clinicians and researchers must pay close 
      attention and exercise caution in assuming changes in patient status that exceed 
      a specific MCID reflect meaningful improvements in health status. A common 
      standard for the calculation and reporting of an MCID is needed to address 
      threats to the validity of conclusions drawn from the interpretation of an MCID.
CI  - Copyright (c) 2024 Wolters Kluwer Health, Inc. All rights reserved.
FAU - Podurgiel, Joseph
AU  - Podurgiel J
AD  - Doctor of Physical Therapy Program, Department of Kinesiology, University of 
      Connecticut, Storrs, Connecticut, USA.
FAU - Piscitelli, Daniele
AU  - Piscitelli D
FAU - Denegar, Craig
AU  - Denegar C
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20240122
PL  - England
TA  - Int J Rehabil Res
JT  - International journal of rehabilitation research. Internationale Zeitschrift fur 
      Rehabilitationsforschung. Revue internationale de recherches de readaptation
JID - 7805421
SB  - IM
MH  - Humans
MH  - Aged
MH  - *Minimal Clinically Important Difference
MH  - *Outcome Assessment, Health Care
MH  - Health Status
MH  - Treatment Outcome
MH  - Patient Reported Outcome Measures
EDAT- 2024/01/22 06:42
MHDA- 2024/02/08 06:43
CRDT- 2024/01/22 05:34
PHST- 2024/02/08 06:43 [medline]
PHST- 2024/01/22 06:42 [pubmed]
PHST- 2024/01/22 05:34 [entrez]
AID - 00004356-990000000-00080 [pii]
AID - 10.1097/MRR.0000000000000613 [doi]
PST - ppublish
SO  - Int J Rehabil Res. 2024 Mar 1;47(1):10-19. doi: 10.1097/MRR.0000000000000613. 
      Epub 2024 Jan 22.