PMID- 38251392
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20240129
IS  - 2076-0817 (Print)
IS  - 2076-0817 (Electronic)
IS  - 2076-0817 (Linking)
VI  - 13
IP  - 1
DP  - 2024 Jan 18
TI  - Presence and Characterisation of Porcine Respirovirus 1 (PRV1) in Northern Italy.
LID - 10.3390/pathogens13010085 [doi]
LID - 85
AB  - Porcine Respirovirus 1 (PRV1) is an enveloped, single-stranded, negative-sense 
      RNA virus belonging to the genus Respirovirus within the Paramyxoviridae family. 
      Since its first detection in China in 2013, PRV1 has been identified in several 
      American and European countries. Although its pathogenicity is uncertain, recent 
      studies have suggested that it may play a role in the Porcine Respiratory Disease 
      Complex (PRDC) because of its capacity to replicate in the upper and lower 
      respiratory tracts. This study aimed to determine the spread of PRV1 in Northern 
      Italy and the phylogeny of the isolates. Therefore, PRV1 was investigated using 
      real-time RT-PCR in 902 samples collected from September 2022 to September 2023 
      from pigs with respiratory symptoms in North Italy. Fourteen (1.55%) samples 
      tested as PRV1-positive. The full-length fusion (F) gene, which codifies for a 
      major surface protein, was amplified and used for phylogenetic analysis to help 
      carry out molecular epidemiological studies on this virus. In addition, swine 
      influenza virus (SIV) and porcine reproductive and respiratory syndrome virus 
      (PRRSV) infections were detected in most of the PRV1-positive samples. In 
      conclusion, we report the detection of PRV1 in Italy and discuss its potential 
      role as a co-factor in causing the Porcine Respiratory Disease Complex.
FAU - Sozzi, Enrica
AU  - Sozzi E
AUID- ORCID: 0000-0002-0144-1217
AD  - Istituto Zooprofilattico Sperimentale della Lombardia e dell'Emilia Romagna 
      "Bruno Ubertini" (IZSLER), Via Antonio Bianchi 7/9, 25124 Brescia, Italy.
FAU - Leo, Gabriele
AU  - Leo G
AD  - Istituto Zooprofilattico Sperimentale della Lombardia e dell'Emilia Romagna 
      "Bruno Ubertini" (IZSLER), Via Antonio Bianchi 7/9, 25124 Brescia, Italy.
FAU - Bertasio, Cristina
AU  - Bertasio C
AUID- ORCID: 0000-0002-1082-982X
AD  - Istituto Zooprofilattico Sperimentale della Lombardia e dell'Emilia Romagna 
      "Bruno Ubertini" (IZSLER), Via Antonio Bianchi 7/9, 25124 Brescia, Italy.
FAU - Alborali, Giovanni Loris
AU  - Alborali GL
AD  - Istituto Zooprofilattico Sperimentale della Lombardia e dell'Emilia Romagna 
      "Bruno Ubertini" (IZSLER), Via Antonio Bianchi 7/9, 25124 Brescia, Italy.
FAU - Salogni, Cristian
AU  - Salogni C
AUID- ORCID: 0000-0003-1443-7214
AD  - Istituto Zooprofilattico Sperimentale della Lombardia e dell'Emilia Romagna 
      "Bruno Ubertini" (IZSLER), Via Antonio Bianchi 7/9, 25124 Brescia, Italy.
FAU - Tonni, Matteo
AU  - Tonni M
AUID- ORCID: 0000-0002-7544-2693
AD  - Istituto Zooprofilattico Sperimentale della Lombardia e dell'Emilia Romagna 
      "Bruno Ubertini" (IZSLER), Via Antonio Bianchi 7/9, 25124 Brescia, Italy.
FAU - Formenti, Nicoletta
AU  - Formenti N
AD  - Istituto Zooprofilattico Sperimentale della Lombardia e dell'Emilia Romagna 
      "Bruno Ubertini" (IZSLER), Via Antonio Bianchi 7/9, 25124 Brescia, Italy.
FAU - Lelli, Davide
AU  - Lelli D
AUID- ORCID: 0000-0002-5775-6058
AD  - Istituto Zooprofilattico Sperimentale della Lombardia e dell'Emilia Romagna 
      "Bruno Ubertini" (IZSLER), Via Antonio Bianchi 7/9, 25124 Brescia, Italy.
FAU - Moreno, Ana
AU  - Moreno A
AUID- ORCID: 0000-0002-8497-9708
AD  - Istituto Zooprofilattico Sperimentale della Lombardia e dell'Emilia Romagna 
      "Bruno Ubertini" (IZSLER), Via Antonio Bianchi 7/9, 25124 Brescia, Italy.
FAU - Trogu, Tiziana
AU  - Trogu T
AD  - Istituto Zooprofilattico Sperimentale della Lombardia e dell'Emilia Romagna 
      "Bruno Ubertini" (IZSLER), Via Antonio Bianchi 7/9, 25124 Brescia, Italy.
FAU - Canziani, Sabrina
AU  - Canziani S
AD  - Istituto Zooprofilattico Sperimentale della Lombardia e dell'Emilia Romagna 
      "Bruno Ubertini" (IZSLER), Via Antonio Bianchi 7/9, 25124 Brescia, Italy.
FAU - Tolini, Clara
AU  - Tolini C
AUID- ORCID: 0000-0002-4527-0210
AD  - Istituto Zooprofilattico Sperimentale della Lombardia e dell'Emilia Romagna 
      "Bruno Ubertini" (IZSLER), Via Antonio Bianchi 7/9, 25124 Brescia, Italy.
FAU - Cerioli, Monica Pierangela
AU  - Cerioli MP
AUID- ORCID: 0000-0002-5114-3728
AD  - Istituto Zooprofilattico Sperimentale della Lombardia e dell'Emilia Romagna 
      "Bruno Ubertini" (IZSLER), Via Antonio Bianchi 7/9, 25124 Brescia, Italy.
FAU - Lavazza, Antonio
AU  - Lavazza A
AUID- ORCID: 0000-0002-7646-3592
AD  - Istituto Zooprofilattico Sperimentale della Lombardia e dell'Emilia Romagna 
      "Bruno Ubertini" (IZSLER), Via Antonio Bianchi 7/9, 25124 Brescia, Italy.
LA  - eng
PT  - Journal Article
DEP - 20240118
PL  - Switzerland
TA  - Pathogens
JT  - Pathogens (Basel, Switzerland)
JID - 101596317
PMC - PMC10819322
OTO - NOTNLM
OT  - Porcine Respirovirus
OT  - epidemiology detection
OT  - phylogenetic analysis
COIS- The authors declare no conflicts of interest.
EDAT- 2024/01/22 06:41
MHDA- 2024/01/22 06:42
PMCR- 2024/01/18
CRDT- 2024/01/22 05:45
PHST- 2023/12/29 00:00 [received]
PHST- 2024/01/12 00:00 [revised]
PHST- 2024/01/16 00:00 [accepted]
PHST- 2024/01/22 06:42 [medline]
PHST- 2024/01/22 06:41 [pubmed]
PHST- 2024/01/22 05:45 [entrez]
PHST- 2024/01/18 00:00 [pmc-release]
AID - pathogens13010085 [pii]
AID - pathogens-13-00085 [pii]
AID - 10.3390/pathogens13010085 [doi]
PST - epublish
SO  - Pathogens. 2024 Jan 18;13(1):85. doi: 10.3390/pathogens13010085.