PMID- 38265185
OWN - NLM
STAT- Publisher
LR  - 20240124
IS  - 1531-4995 (Electronic)
IS  - 0023-852X (Linking)
DP  - 2024 Jan 24
TI  - Partial Ossicular Reconstruction With a Novel Ball Joint Prosthesis: The mCLIP 
      ARC Partial Prosthesis.
LID - 10.1002/lary.31301 [doi]
AB  - OBJECTIVE: Middle ear surgery involves reconstruction of the ossicular chain, 
      predominately using rigid implants. New middle ear prostheses strive to mimic the 
      physiologic micromovements of the ossicular chain and prevent dislocation, 
      protrusion, and preloading of the annular ligament due to pressure fluctuations. 
      METHODS: Thirty-five patients were included in a monocentric, prospective 
      observational study. Patients received tympanoplasty with ossicular 
      reconstruction using the mCLIP ARC partial prosthesis. This titanium prosthesis 
      is equipped with a clip mechanism for coupling at the stapes and a ball joint 
      connecting headplate and shaft. At short-term (ST) and mid-term (MT) follow-up, 
      pure-tone audiometry was performed and the pure tone average of 0.5, 1, 2, and 
      3 kHz (PTA4) was calculated. The audiological outcome was compared with 
      retrospective data of the Dresden titanium clip prosthesis. RESULTS: The new 
      prosthesis shows favorable clinical results. Pure-tone audiometry showed 
      satisfactory results in ST and MT follow-up, with the PTA4 air-bone gap (ABG) 
      decreasing from 24.5 (+/-11) dB to 17.4 (+/-7.9) dB at the ST follow-up at 27 days to 
      15.6 (+/-10.3) dB at MT follow-up at 196 days (n = 32). A PTA4-ABG value of less 
      than 20 dB was achieved by 63% of patients at ST follow-up and by 77% at MT 
      follow-up. There was no significant difference in PTA4 ABG compared to the 
      Dresden titanium clip prosthesis during ST follow-up (p = 0.18). CONCLUSION: The 
      mCLIP ARC partial prosthesis, a new middle ear prosthesis with a balanced ball 
      joint, shows promising audiological results and is a safe and effective choice 
      for patients with chronic ear disease. LEVEL OF EVIDENCE: 3 Laryngoscope, 2024.
CI  - (c) 2024 The Authors. The Laryngoscope published by Wiley Periodicals LLC on behalf 
      of The American Laryngological, Rhinological and Otological Society, Inc.
FAU - Bevis, Nicholas
AU  - Bevis N
AUID- ORCID: 0000-0002-1667-1365
AD  - Department of Otorhinolaryngology, Head and Neck Surgery, University Medical 
      Center Gottingen, 37075, Gottingen, Germany.
FAU - Effertz, Thomas
AU  - Effertz T
AD  - Department of Otorhinolaryngology, Head and Neck Surgery, University Medical 
      Center Gottingen, 37075, Gottingen, Germany.
FAU - Huser, Marc
AU  - Huser M
AD  - Department of Otorhinolaryngology, Head and Neck Surgery, University Medical 
      Center Gottingen, 37075, Gottingen, Germany.
FAU - Beutner, Dirk
AU  - Beutner D
AD  - Department of Otorhinolaryngology, Head and Neck Surgery, University Medical 
      Center Gottingen, 37075, Gottingen, Germany.
LA  - eng
GR  - MED-EL/
PT  - Journal Article
DEP - 20240124
PL  - United States
TA  - Laryngoscope
JT  - The Laryngoscope
JID - 8607378
SB  - IM
OTO - NOTNLM
OT  - ball joint
OT  - middle ear prosthesis
OT  - partial ossicular replacement prosthesis
EDAT- 2024/01/24 12:44
MHDA- 2024/01/24 12:44
CRDT- 2024/01/24 09:10
PHST- 2023/11/30 00:00 [revised]
PHST- 2023/09/20 00:00 [received]
PHST- 2024/01/05 00:00 [accepted]
PHST- 2024/01/24 12:44 [medline]
PHST- 2024/01/24 12:44 [pubmed]
PHST- 2024/01/24 09:10 [entrez]
AID - 10.1002/lary.31301 [doi]
PST - aheadofprint
SO  - Laryngoscope. 2024 Jan 24. doi: 10.1002/lary.31301.