PMID- 38275790 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20240128 IS - 2076-2615 (Print) IS - 2076-2615 (Electronic) IS - 2076-2615 (Linking) VI - 14 IP - 2 DP - 2024 Jan 21 TI - Evaluation of the Audicor Acoustic Cardiography Device as a Diagnostic Tool in Horses with Mitral or Aortic Valve Insufficiency. LID - 10.3390/ani14020331 [doi] LID - 331 AB - Mitral and aortic valve insufficiencies have been commonly reported in horses. The objective of this study was to establish the use of acoustic cardiography (Audicor((R))) in horses with aortic (AI) or mitral valve insufficiency (MI). A total of 17 healthy horses, 18 horses with AI, and 28 horses with MI were prospectively included. None of the horses was in heart failure. Echocardiography and Audicor((R)) analyses were conducted. Electromechanical activating time (EMAT), rate-corrected EMATc, left ventricular systolic time (LVST), rate-corrected LVSTc, and intensity and persistence of the third and fourth heart sound (S3, S4) were reported by Audicor((R)). Graphical analysis of the three-dimensional (3D) phonocardiogram served to visually detect murmurs. Audicor((R)) snapshot variables were compared between groups using one-way ANOVA followed by Tukey's multiple-comparisons test. The association between Audicor((R)) snapshot variables and the corresponding echocardiographic variables was investigated by linear regression and Bland-Altman analyses. Heart murmurs were not displayed on Audicor((R)) phonocardiograms. No significant differences were found between Audicor((R)) variables obtained in clinically healthy horses and horses with valvular insufficiency. The Audicor((R)) device is unable to detect heart murmurs in horses. Audicor((R)) variables representing cardiac function are not markedly altered, and their association with corresponding echocardiographic variables is poor in horses with valvular insufficiency that are not in heart failure. FAU - Piotrowski, Isabelle L AU - Piotrowski IL AUID- ORCID: 0000-0001-5130-5021 AD - Clinic for Equine Internal Medicine, Vetsuisse Faculty, University of Zurich, 8057 Zurich, Switzerland. FAU - Junge, Hannah K AU - Junge HK AUID- ORCID: 0000-0001-6258-541X AD - Clinic for Equine Internal Medicine, Vetsuisse Faculty, University of Zurich, 8057 Zurich, Switzerland. FAU - Schwarzwald, Colin C AU - Schwarzwald CC AUID- ORCID: 0000-0002-6095-5402 AD - Clinic for Equine Internal Medicine, Vetsuisse Faculty, University of Zurich, 8057 Zurich, Switzerland. LA - eng PT - Journal Article DEP - 20240121 PL - Switzerland TA - Animals (Basel) JT - Animals : an open access journal from MDPI JID - 101635614 PMC - PMC10812805 OTO - NOTNLM OT - cardiovascular OT - heart murmurs OT - heart sounds OT - horse OT - phonocardiogram COIS- The authors declare no conflicts of interest. EDAT- 2024/01/26 12:45 MHDA- 2024/01/26 12:46 PMCR- 2024/01/21 CRDT- 2024/01/26 09:16 PHST- 2023/12/10 00:00 [received] PHST- 2024/01/09 00:00 [revised] PHST- 2024/01/17 00:00 [accepted] PHST- 2024/01/26 12:46 [medline] PHST- 2024/01/26 12:45 [pubmed] PHST- 2024/01/26 09:16 [entrez] PHST- 2024/01/21 00:00 [pmc-release] AID - ani14020331 [pii] AID - animals-14-00331 [pii] AID - 10.3390/ani14020331 [doi] PST - epublish SO - Animals (Basel). 2024 Jan 21;14(2):331. doi: 10.3390/ani14020331.