PMID- 38283384
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20240131
IS  - 2090-2867 (Print)
IS  - 2090-2875 (Electronic)
IS  - 2090-2867 (Linking)
VI  - 2024
DP  - 2024
TI  - Exercise-Induced Functional Changes in People with Parkinson's Disease following 
      External Cueing and Task-Based Intervention.
PG  - 6188546
LID - 10.1155/2024/6188546 [doi]
LID - 6188546
AB  - INTRODUCTION: The purpose of this study was to evaluate change in motor function, 
      gait speed, dynamic balance, balance confidence, and quality of life (QoL) in 
      nine participants with Parkinson's disease (PwPD) completing Lee Silverman Voice 
      Treatment BIG (LSVT-BIG), an external cueing and task-based intervention. 
      Although supported as an efficacious treatment in PwPD, there is limited research 
      examining clinically meaningful change in outcome measures related to external 
      cueing and task-based interventions. MATERIALS AND METHODS: This was a case 
      series of nine PwPD (age range 64-76 years, 55% male) who completed the LSVT-BIG 
      protocol. Disease duration ranged from 1 to 17 years and was classified as 
      moderate in all participants (Hoehn and Yahr = 2 or 3). Outcome measures included 
      motor function (MDS-UPDRS Part III Motor), gait speed, dynamic balance 
      (MiniBEST), Activities-specific Balance Confidence (ABC), and Summary Index for 
      PD Quality of Life 39 (PDQ-SI). Assessments were completed at baseline (BASE), 
      end of treatment (EOT), and 4 weeks after EOT (EOT+4). RESULTS: Minimal 
      detectable change (MDC) or minimal clinical important difference (MCID) was 
      observed in one or more outcome measures in 8 of 9 participants at EOT and EOT+4 
      across domains of motor function (67%, 78%), gait speed (78%, 67%), balance 
      confidence (44%, 33%), quality of life (44%, 78%), and dynamic balance (22%, 
      22%). Discussion. In this case series, 8 of 9 participants showed MDC or MCID 
      changes across multiple functional domains. Improvements were observed 
      immediately post (EOT) and 4-week post-treatment (EOT+4) suggesting a temporal 
      component of the LSVT-BIG impact on functional change. Future research should 
      include clinical trials to examine additional external cueing and task-based 
      intervention efficacy with consideration of intensity, frequency, and mode of 
      delivery across disease severity.
CI  - Copyright (c) 2024 Christine M. Clarkin et al.
FAU - Clarkin, Christine M
AU  - Clarkin CM
AUID- ORCID: 0000-0002-9082-4083
AD  - Physical Therapy Department, University of Rhode Island, Kingston, Rhode Island, 
      USA.
AD  - Interdisciplinary Neuroscience Program, University of Rhode Island, Kingston, 
      Rhode Island, USA.
FAU - Ward-Ritacco, Christie L
AU  - Ward-Ritacco CL
AUID- ORCID: 0000-0002-7565-3490
AD  - Interdisciplinary Neuroscience Program, University of Rhode Island, Kingston, 
      Rhode Island, USA.
AD  - Department of Kinesiology, University of Rhode Island, Kingston, Rhode Island, 
      USA.
FAU - Mahler, Leslie
AU  - Mahler L
AD  - Interdisciplinary Neuroscience Program, University of Rhode Island, Kingston, 
      Rhode Island, USA.
AD  - Department of Communicative Disorders, University of Rhode Island, Kingston, 
      Rhode Island, USA.
LA  - eng
PT  - Journal Article
DEP - 20240119
PL  - United States
TA  - Rehabil Res Pract
JT  - Rehabilitation research and practice
JID - 101566862
PMC - PMC10817815
COIS- The authors declare that there are no conflicts of interest relevant to this 
      work.
EDAT- 2024/01/29 06:44
MHDA- 2024/01/29 06:45
PMCR- 2024/01/19
CRDT- 2024/01/29 04:27
PHST- 2022/11/10 00:00 [received]
PHST- 2023/08/09 00:00 [revised]
PHST- 2023/12/23 00:00 [accepted]
PHST- 2024/01/29 06:45 [medline]
PHST- 2024/01/29 06:44 [pubmed]
PHST- 2024/01/29 04:27 [entrez]
PHST- 2024/01/19 00:00 [pmc-release]
AID - 10.1155/2024/6188546 [doi]
PST - epublish
SO  - Rehabil Res Pract. 2024 Jan 19;2024:6188546. doi: 10.1155/2024/6188546. 
      eCollection 2024.