PMID- 38283928
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20240131
IS  - 2451-0629 (Print)
IS  - 2451-0629 (Electronic)
IS  - 2451-0629 (Linking)
VI  - 8
DP  - 2023
TI  - Comparison of angiographic estimation and invasive hemodynamic measurement of the 
      significance of non-infarct-related residual stenoses in ST-elevation myocardial 
      infarction patients.
PG  - e169-e176
LID - 10.5114/amsad/172971 [doi]
AB  - INTRODUCTION: Up to 50% of patients with ST elevation myocardial infarction 
      (STEMI) have >/= 50% stenosis in a major non-infarct-related artery. Several 
      studies have evaluated the prognostic value of the completion of 
      revascularization with overall inconclusive results. Selection of the stenoses 
      was based on the angiographic evaluation, invasive hemodynamic measurement or the 
      combined approach. It is unknown whether such a selection provides correlation of 
      comparable patient groups. MATERIAL AND METHODS: We enrolled 51 patients (62.7 
      +/-10.2 years) with acute STEMI and at least one residual (50-90%) stenosis in a 
      non-infarct-related major coronary artery (excluding left main coronary artery). 
      Overall 65 stenoses (67.9 +/-10.7%) were evaluated angiographically following 
      primary percutaneous coronary intervention and the hemodynamic significance was 
      estimated with respect to the stenosis severity, caliber of the arterial segment, 
      localization of the stenosis (proximity) as well as the estimated size of the 
      supplied vascular territory. During subsequent hospitalization, invasive 
      measurement of the hemodynamic significance using fractional flow reserve (FFR) 
      was performed to guide the final revascularization strategy (FFR value of </= 0.80 
      considered significant). RESULTS: Based on angiographic evaluation, a total of 44 
      stenoses would be recommended for treatment, whereas only 31 stenoses were 
      revascularized based on FFR measurement. Moreover, visual evaluation and 
      hemodynamic measurement were discrepant in 27 of 65 (41.5%) stenoses. 
      CONCLUSIONS: We observed a weak correlation between visual angiographic 
      evaluation and invasive hemodynamic measurement. More stents would be implanted 
      based on angiographic evaluation compared to FFR measurement.
CI  - Copyright: (c) 2023 Termedia & Banach.
FAU - Spacek, Miloslav
AU  - Spacek M
AD  - Department of Internal Medicine I - Cardiology, Faculty of Medicine and 
      Dentistry, Palacky University Olomouc and University Hospital Olomouc, Olomouc, 
      Czech Republic.
FAU - Vacha, Jan
AU  - Vacha J
AD  - Department of Internal Medicine I - Cardiology, Faculty of Medicine and 
      Dentistry, Palacky University Olomouc and University Hospital Olomouc, Olomouc, 
      Czech Republic.
FAU - Kaminek, Milan
AU  - Kaminek M
AD  - Department of Nuclear Medicine, Faculty of Medicine and Dentistry, Palacky 
      University Olomouc and University Hospital Olomouc, Olomouc, Czech Republic.
FAU - Hutyra, Martin
AU  - Hutyra M
AD  - Department of Internal Medicine I - Cardiology, Faculty of Medicine and 
      Dentistry, Palacky University Olomouc and University Hospital Olomouc, Olomouc, 
      Czech Republic.
FAU - Nykl, Radomir
AU  - Nykl R
AD  - Department of Internal Medicine I - Cardiology, Faculty of Medicine and 
      Dentistry, Palacky University Olomouc and University Hospital Olomouc, Olomouc, 
      Czech Republic.
FAU - Sluka, Martin
AU  - Sluka M
AD  - Department of Internal Medicine I - Cardiology, Faculty of Medicine and 
      Dentistry, Palacky University Olomouc and University Hospital Olomouc, Olomouc, 
      Czech Republic.
FAU - Taborsky, Milos
AU  - Taborsky M
AD  - Department of Internal Medicine I - Cardiology, Faculty of Medicine and 
      Dentistry, Palacky University Olomouc and University Hospital Olomouc, Olomouc, 
      Czech Republic.
LA  - eng
PT  - Journal Article
DEP - 20231230
PL  - Poland
TA  - Arch Med Sci Atheroscler Dis
JT  - Archives of medical sciences. Atherosclerotic diseases
JID - 101701205
PMC - PMC10811533
OTO - NOTNLM
OT  - acute ST elevation myocardial infarction
OT  - atherosclerosis
OT  - complete revascularization
OT  - coronary flow
OT  - fractional flow reserve
OT  - infarct-related artery
OT  - multivessel coronary artery disease
COIS- The authors declare no conflict of interest.
EDAT- 2024/01/29 06:42
MHDA- 2024/01/29 06:43
PMCR- 2023/12/30
CRDT- 2024/01/29 04:47
PHST- 2023/08/18 00:00 [received]
PHST- 2023/09/27 00:00 [accepted]
PHST- 2024/01/29 06:43 [medline]
PHST- 2024/01/29 06:42 [pubmed]
PHST- 2024/01/29 04:47 [entrez]
PHST- 2023/12/30 00:00 [pmc-release]
AID - 172971 [pii]
AID - 10.5114/amsad/172971 [doi]
PST - epublish
SO  - Arch Med Sci Atheroscler Dis. 2023 Dec 30;8:e169-e176. doi: 10.5114/amsad/172971. 
      eCollection 2023.