PMID- 38292460 OWN - NLM STAT- MEDLINE DCOM- 20240201 LR - 20240206 IS - 1178-1998 (Electronic) IS - 1176-9092 (Print) IS - 1176-9092 (Linking) VI - 19 DP - 2024 TI - Imaging of Sarcopenia in Type 2 Diabetes Mellitus. PG - 141-151 LID - 10.2147/CIA.S443572 [doi] AB - Sarcopenia is an age-related condition characterized by the loss of skeletal muscle mass, muscular strength, and muscle function. In older adults, type 2 diabetes mellitus (T2DM) constitutes a significant health burden. Skeletal muscle damage and deterioration have emerged as novel chronic complications in patients with diabetes, often linked to their increased longevity. Diabetic sarcopenia has been associated with increased rates of hospitalization, cardiovascular events, and mortality. Nevertheless, effectively managing metabolic disorders in patients with T2DM through appropriate therapeutic interventions could potentially mitigate the risk of sarcopenia. Utilizing imaging technologies holds substantial clinical significance in the early detection of skeletal muscle mass alterations associated with sarcopenia. Such detection is pivotal for arresting disease progression and preserving patients' quality of life. These imaging modalities offer reproducible and consistent patterns over time, as they all provide varying degrees of quantitative data. This review primarily delves into the application of dual-energy X-ray absorptiometry, computed tomography, magnetic resonance imaging, and ultrasound for both qualitative and quantitative assessments of muscle mass in patients with T2DM. It also juxtaposes the merits and limitations of these four techniques. By understanding the nuances of each method, clinicians can discern how best to apply them in diverse clinical scenarios. CI - (c) 2024 Wang et al. FAU - Wang, Dingyue AU - Wang D AD - Department of Ultrasound, the First Affiliated Hospital China Medical University, Shenyang City, Liaoning Province, 110001, People's Republic of China. FAU - Zhang, Gaosen AU - Zhang G AD - Department of Ultrasound, the First Affiliated Hospital China Medical University, Shenyang City, Liaoning Province, 110001, People's Republic of China. FAU - Yu, Yana AU - Yu Y AD - Department of Ultrasound, the First Affiliated Hospital China Medical University, Shenyang City, Liaoning Province, 110001, People's Republic of China. FAU - Zhang, Zhen AU - Zhang Z AD - Department of Ultrasound, the First Affiliated Hospital China Medical University, Shenyang City, Liaoning Province, 110001, People's Republic of China. LA - eng PT - Journal Article PT - Review DEP - 20240126 PL - New Zealand TA - Clin Interv Aging JT - Clinical interventions in aging JID - 101273480 SB - IM MH - Humans MH - Aged MH - *Sarcopenia/diagnostic imaging/etiology MH - *Diabetes Mellitus, Type 2/complications/diagnostic imaging MH - Muscle, Skeletal/pathology MH - Quality of Life MH - Muscle Strength/physiology PMC - PMC10826713 OTO - NOTNLM OT - diagnostic imaging OT - older adults OT - sarcopenia OT - skeletal muscle mass OT - type 2 diabetes mellitus COIS- The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. EDAT- 2024/01/31 06:43 MHDA- 2024/02/01 06:42 PMCR- 2024/01/26 CRDT- 2024/01/31 04:11 PHST- 2023/10/07 00:00 [received] PHST- 2024/01/17 00:00 [accepted] PHST- 2024/02/01 06:42 [medline] PHST- 2024/01/31 06:43 [pubmed] PHST- 2024/01/31 04:11 [entrez] PHST- 2024/01/26 00:00 [pmc-release] AID - 443572 [pii] AID - 10.2147/CIA.S443572 [doi] PST - epublish SO - Clin Interv Aging. 2024 Jan 26;19:141-151. doi: 10.2147/CIA.S443572. eCollection 2024.