PMID- 38292592 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20240201 IS - 2364-3722 (Print) IS - 2196-9736 (Electronic) IS - 2196-9736 (Linking) VI - 12 IP - 1 DP - 2024 Jan TI - Risk factors of early adverse events associated with endoscopic ultrasound-guided hepaticogastrostomy using self-expandable metal stent. PG - E164-E175 LID - 10.1055/a-2240-1100 [doi] AB - Background and study aims This retrospective study aimed to investigate risk factors for early adverse events (AEs) associated with endoscopic ultrasonography-guided hepaticogastrostomy (EUS-HGS) using self-expandable metal stents (SEMS). Patients and methods The clinical success rate, technical success rate, and early AEs were assessed at two hospitals from 2010 to 2022. The analysis focused on risk factors associated with cholangitis, peritonitis, and SEMS migration. Results Technical success was achieved in all cases (94/94), and clinical success was 96.8% (91/94). Post-procedural acute cholangitis occurred in 12.8%of cases (12/94). However, no statistically significant risk factors were identified for cholangitis or biliary tract infection. Peritonitis occurred in only 2.1% of cases (2/94). Univariate analysis, using a 1.5 cm cut-off for the distance between the liver and gastrointestinal tract, revealed significant risk factors: braided-type SEMS, bile duct diameter (especially >4 mm), 6 mm diameter SEMS, and tract dilation ( P= 0.001, P= 0.020, P =0.023, and P =0.046, respectively). Adjusting the cut-offs to 2 cm underscored braided-type SEMS and tract dilation as risk factors ( P =0.002 and P =0.046, respectively). With 2.5-cm cut-offs, only braided-type SEMS remained significant ( P =0.018). Mortality within 14 and 30 days following EUS-HGS was 5.3% (5/94) and 16.0% (15/94), respectively. Conclusions EUS-HGS using SEMS demonstrated high technical and clinical success rates. Laser-cut SEMS may be superior in preventing early AEs. CI - The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/). FAU - Nakaji, So AU - Nakaji S AUID- ORCID: 0000-0001-7955-6092 AD - Gastroenterology, Kameda Medical Center, Kamogawa, Japan. RINGGOLD: 13770 AD - Department of Metabolism and Endocrinology, Saga Medical School Faculty of Medicine, Saga University, Saga, Japan. RINGGOLD: 13030 FAU - Takahashi, Hirokazu AU - Takahashi H AD - Department of Metabolism and Endocrinology, Saga Medical School Faculty of Medicine, Saga University, Saga, Japan. RINGGOLD: 13030 FAU - Yoshioka, Wataru AU - Yoshioka W AD - Gastroenterology, Kameda Medical Center, Kamogawa, Japan. RINGGOLD: 13770 FAU - Shiratori, Toshiyasu AU - Shiratori T AD - Gastroenterology, Kameda Medical Center, Kamogawa, Japan. RINGGOLD: 13770 FAU - Yoshimura, Shigenobu AU - Yoshimura S AD - Gastroenterology, Kameda Medical Center, Kamogawa, Japan. RINGGOLD: 13770 FAU - Kawamitsu, Natsuki AU - Kawamitsu N AD - Gastroenterology, Kameda Medical Center, Kamogawa, Japan. RINGGOLD: 13770 FAU - Tomonari, Akiko AU - Tomonari A AD - Department of Gastroenterology, ParkwayHealth China, Shanghai, China. RINGGOLD: 159398 LA - eng PT - Journal Article DEP - 20240130 PL - Germany TA - Endosc Int Open JT - Endoscopy international open JID - 101639919 PMC - PMC10827478 OTO - NOTNLM OT - Biliary tract OT - Endoscopic ultrasonography OT - Intervention EUS OT - Pancreas COIS- Conflict of Interest The authors declare that they have no conflict of interest. EDAT- 2024/01/31 06:42 MHDA- 2024/01/31 06:43 PMCR- 2024/01/01 CRDT- 2024/01/31 04:13 PHST- 2023/10/09 00:00 [received] PHST- 2024/01/04 00:00 [accepted] PHST- 2024/01/31 06:43 [medline] PHST- 2024/01/31 06:42 [pubmed] PHST- 2024/01/31 04:13 [entrez] PHST- 2024/01/01 00:00 [pmc-release] AID - EIO-2023-10-3171-OA [pii] AID - 10.1055/a-2240-1100 [doi] PST - epublish SO - Endosc Int Open. 2024 Jan 30;12(1):E164-E175. doi: 10.1055/a-2240-1100. eCollection 2024 Jan.