PMID- 38293304 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20240201 IS - 2296-858X (Print) IS - 2296-858X (Electronic) IS - 2296-858X (Linking) VI - 10 DP - 2023 TI - Critical importance of patient-reported outcomes for a comprehensive assessment of psoriatic arthritis patients. PG - 1332432 LID - 10.3389/fmed.2023.1332432 [doi] LID - 1332432 AB - INTRODUCTION: Psoriatic arthritis (PsA) is a heterogeneous, chronic inflammatory disease that negatively impacts patients' quality of life. Patient-reported outcome measures (PROMs) are used to capture patient perspectives in disease assessment, and physicians use the Disease Activity Index for Psoriatic Arthritis (DAPSA) to evaluate disease activity in PsA. The study aimed to assess the relationship between PROMs and the DAPSA score in consecutive outpatients affected by PsA. MATERIALS AND METHODS: A cross-sectional study was conducted from March 2018 to October 2020 at the PsA clinic of the ARNAS Civico in Palermo (Italy), enrolling outpatients with PsA. Patients were assessed for their disease activity according to the DAPSA score, and PROMs, such as PHQ-9, HAQ, FACIT-F, and PsAID, were evaluated. Linear regression analysis evaluated the relationship between the DAPSA Score and the included PROMs. RESULTS: 158 PsA consecutive peripheral subset psoriatic arthritis outpatients were recruited. The median years of illness was 10.6 (9.3-11.9), and the median DAPSA score was 19.02 (9-33.1). The regression analysis highlighted a strong relationship between the DAPSA score and the PsAID (adjR(2) 26%, p < 0.0001), the FACIT-F (adjR(2) 25.4%, p < 0.0001), the HAQ (adjR(2) 23.7%, p < 0.0001), and PHQ-9 (adjR(2) 15%, p < 0.0001). CONCLUSION: PROMs are strongly associated with the DAPSA score, but it allows in-depth evaluation of the impact of the disease on different domains of PsA patients' life. CI - Copyright (c) 2024 Lo Monaco, Mallaci Bocchio, Natoli, Giardina, Cangemi, Scibetta, Argano and Corrao. FAU - Lo Monaco, Marika AU - Lo Monaco M AD - Department of Health Promotion Sciences, Maternal and Infant Care, Internal Medicine and Medical Specialties [PROMISE], University of Palermo, Palermo, Italy. AD - Department of Clinical Medicine, Internal Medicine Unit with Rheumatology, Dermatology, Diabetology and Tertiary Diabetic Foot Healthcare, National Relevance and High Specialization Hospital Trust ARNAS Civico, Di Cristina, Benfratelli, Palermo, Italy. FAU - Mallaci Bocchio, Raffaella AU - Mallaci Bocchio R AD - Department of Clinical Medicine, Internal Medicine Unit with Rheumatology, Dermatology, Diabetology and Tertiary Diabetic Foot Healthcare, National Relevance and High Specialization Hospital Trust ARNAS Civico, Di Cristina, Benfratelli, Palermo, Italy. FAU - Natoli, Giuseppe AU - Natoli G AD - Department of Clinical Medicine, Internal Medicine Unit with Rheumatology, Dermatology, Diabetology and Tertiary Diabetic Foot Healthcare, National Relevance and High Specialization Hospital Trust ARNAS Civico, Di Cristina, Benfratelli, Palermo, Italy. FAU - Giardina, Annarita AU - Giardina A AD - Department of Clinical Medicine, Internal Medicine Unit with Rheumatology, Dermatology, Diabetology and Tertiary Diabetic Foot Healthcare, National Relevance and High Specialization Hospital Trust ARNAS Civico, Di Cristina, Benfratelli, Palermo, Italy. FAU - Cangemi, Ignazio AU - Cangemi I AD - Department of Clinical Medicine, Internal Medicine Unit with Rheumatology, Dermatology, Diabetology and Tertiary Diabetic Foot Healthcare, National Relevance and High Specialization Hospital Trust ARNAS Civico, Di Cristina, Benfratelli, Palermo, Italy. FAU - Scibetta, Salvatore AU - Scibetta S AD - Department of Clinical Medicine, Internal Medicine Unit with Rheumatology, Dermatology, Diabetology and Tertiary Diabetic Foot Healthcare, National Relevance and High Specialization Hospital Trust ARNAS Civico, Di Cristina, Benfratelli, Palermo, Italy. FAU - Argano, Christiano AU - Argano C AD - Department of Clinical Medicine, Internal Medicine Unit with Rheumatology, Dermatology, Diabetology and Tertiary Diabetic Foot Healthcare, National Relevance and High Specialization Hospital Trust ARNAS Civico, Di Cristina, Benfratelli, Palermo, Italy. FAU - Corrao, Salvatore AU - Corrao S AD - Department of Health Promotion Sciences, Maternal and Infant Care, Internal Medicine and Medical Specialties [PROMISE], University of Palermo, Palermo, Italy. AD - Department of Clinical Medicine, Internal Medicine Unit with Rheumatology, Dermatology, Diabetology and Tertiary Diabetic Foot Healthcare, National Relevance and High Specialization Hospital Trust ARNAS Civico, Di Cristina, Benfratelli, Palermo, Italy. LA - eng PT - Journal Article DEP - 20240116 PL - Switzerland TA - Front Med (Lausanne) JT - Frontiers in medicine JID - 101648047 PMC - PMC10826607 OTO - NOTNLM OT - disease activity OT - multidimensional assessment OT - nurse assessment OT - nursing OT - patient reported outcomes OT - psoriatic disease OT - quality of life OT - rheumatology COIS- The authors declare that the research was conducted without any commercial or financial relationships that could be construed as a potential conflict of interest. The author(s) declared that they were an editorial board member of Frontiers, at the time of submission. This had no impact on the peer review process and the final decision. EDAT- 2024/01/31 06:43 MHDA- 2024/01/31 06:44 PMCR- 2024/01/16 CRDT- 2024/01/31 04:23 PHST- 2023/11/02 00:00 [received] PHST- 2023/12/28 00:00 [accepted] PHST- 2024/01/31 06:44 [medline] PHST- 2024/01/31 06:43 [pubmed] PHST- 2024/01/31 04:23 [entrez] PHST- 2024/01/16 00:00 [pmc-release] AID - 10.3389/fmed.2023.1332432 [doi] PST - epublish SO - Front Med (Lausanne). 2024 Jan 16;10:1332432. doi: 10.3389/fmed.2023.1332432. eCollection 2023.