PMID- 38299087
OWN - NLM
STAT- MEDLINE
DCOM- 20240202
LR  - 20240206
IS  - 1986-5961 (Electronic)
IS  - 0350-199X (Print)
IS  - 0350-199X (Linking)
VI  - 77
IP  - 5
DP  - 2023
TI  - Indoor Aeroallergen Sensitization and Associated Factors in Hospitalized Children 
      with Asthma Exacerbations.
PG  - 338-344
LID - 10.5455/medarh.2023.77.338-344 [doi]
AB  - BACKGROUND: Allergic asthma represents the most popular phenotype of childhood 
      asthma and is characterized by eosinophilic airway inflammation associated with 
      specific immunoglobulin E (IgE) antibodies sensitization to various allergens, as 
      evidenced by serology or skin prick test.(2) Sensitization to indoor 
      aeroallergens is associated with severe asthma and severe asthma exacerbations. 
      OBJECTIVE: This study aimed to identify the prevalence of aeroallergen 
      sensitization and its associated factors in children with an asthma exacerbation 
      in Vietnam. METHODS: A cross-sectional study was conducted at Children's Hospital 
      1, Ho Chi Minh City (HCMC). Children who were aged 3 to 15 and admitted to the 
      hospital with moderate or severe asthma exacerbation were recruited to the study. 
      Data was collected from interviews and medical records. SPT was used to identify 
      aeroallergen sensitization. The association between school-age, living area, and 
      passive smoking with the odds of aeroallergen sensitization was assessed using a 
      multivariable logistic regression. RESULTS: The prevalence of aeroallergen 
      sensitization was 82.6% and this figure in school-age children was higher than 
      that in preschool-age ones (93.8% vs 72.1%, p=0.001). School-age, living in HCMC, 
      and passive smoking significantly increased the odds of aeroallergen 
      sensitization in asthmatic children with adjusted OR [95%CI] as 6.9 [2.1-23.3], 
      4.1 [1.5-11.5], and 2.9 [1.0-8.4], respectively. Asthmatic children with 
      aeroallergen sensitization required more hours to resolve an asthma exacerbation 
      than those without (22.4 vs 15.2, p=0.006). CONCLUSION: Aeroallergen 
      sensitization was common in hospitalized children with moderate or severe asthma 
      exacerbation. It is necessary to establish environmental policy and screening 
      practices of aeroallergen sensitization to improve the quality of asthma 
      management for Vietnamese children.
CI  - (c) 2023 Nguyen Thuy Van Thao, To Gia Kien, Tran Anh Tuan, Nguyen Minh Duc, Phan 
      Minh Hoang, Le Thuong Vu.
FAU - Thao, Nguyen Thuy Van
AU  - Thao NTV
AD  - Department of Pediatrics, Faculty of Medicine, University of Medicine and 
      Pharmacy at Ho Chi Minh City, Ho Chi Minh City, Vietnam.
AD  - Department of General Internal Medicine 2, Children's Hospital 1, Ho Chi Minh 
      City, Vietnam.
FAU - Kien, To Gia
AU  - Kien TG
AD  - Department of Health Management, Faculty of Public Health, University of Medicine 
      and Pharmacy at Ho Chi Minh City, Ho Chi Minh City, Vietnam.
FAU - Tuan, Tran Anh
AU  - Tuan TA
AD  - Department of Respirology, Children's Hospital 1, Ho Chi Minh City, Vietnam.
FAU - Duc, Nguyen Minh
AU  - Duc NM
AD  - Department of Radiology, Pham Ngoc Thach University of Medicine, Ho Chi Minh 
      City, Vietnam.
FAU - Hoang, Phan Minh
AU  - Hoang PM
AD  - Department of Physical therapy and Rehabilitation, Pham Ngoc Thach University of 
      Medicine, Ho Chi Minh City, Vietnam.
AD  - Director board, HCMC Hospital for Rehabilitation-Professional diseases.
FAU - Vu, Le Thuong
AU  - Vu LT
AD  - Department of Internal Medicine, Faculty of Medicine, University of Medicine and 
      Pharmacy at Ho Chi Minh City, Ho Chi Minh City, Vietnam.
AD  - Department of Respirology, University Medical Center, Ho Chi Minh City, Vietnam.
LA  - eng
PT  - Journal Article
PL  - Bosnia and Herzegovina
TA  - Med Arch
JT  - Medical archives (Sarajevo, Bosnia and Herzegovina)
JID - 101635337
RN  - 0 (Tobacco Smoke Pollution)
RN  - 0 (Allergens)
SB  - IM
MH  - Child
MH  - Child, Preschool
MH  - Humans
MH  - *Tobacco Smoke Pollution
MH  - Child, Hospitalized
MH  - Cross-Sectional Studies
MH  - *Asthma/diagnosis
MH  - Allergens
MH  - Skin Tests
PMC - PMC10825742
OTO - NOTNLM
OT  - aeroallergen sensitization
OT  - pediatric asthma exacerbation
OT  - skin prick test
EDAT- 2023/01/01 00:00
MHDA- 2024/02/02 06:43
PMCR- 2023/01/01
CRDT- 2024/02/01 04:26
PHST- 2023/09/12 00:00 [received]
PHST- 2023/10/17 00:00 [accepted]
PHST- 2024/02/02 06:43 [medline]
PHST- 2023/01/01 00:00 [pubmed]
PHST- 2024/02/01 04:26 [entrez]
PHST- 2023/01/01 00:00 [pmc-release]
AID - 10.5455/medarh.2023.77.338-344 [doi]
PST - ppublish
SO  - Med Arch. 2023;77(5):338-344. doi: 10.5455/medarh.2023.77.338-344.