PMID- 38304065 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20240203 IS - 2214-4420 (Print) IS - 2214-4420 (Electronic) IS - 2214-4420 (Linking) VI - 53 DP - 2024 Mar TI - Primary sclerosing epithelioid fibrosarcoma of the kidney: A rare case report. PG - 102657 LID - 10.1016/j.eucr.2024.102657 [doi] LID - 102657 AB - Sclerosing epithelioid fibrosarcoma (SEF) represents a rare variant of fibrosarcoma primarily arising in the deep soft tissue of the extremities and trunk. The author reported a rare case of SEF emerged primarily in the kidney. Clinically, the patient complained of hematuria. The diagnosis was confirmed by histological examination and immunohistochemical staining of MUC4. Subsequent fluorescence in situ hybridization (FISH) analysis detected the presence of EWSR1 gene rearrangement, further confirming the histological diagnosis. The patient has been alive with 12 months follow-ups after nephrectomy. The disease should be considered in the differential diagnosis for primary renal tumors. CI - (c) 2024 The Authors. FAU - Wu, Kuan-Hsien AU - Wu KH AD - Department of Urology, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan. AD - Graduate Institute of Clinical Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan. FAU - Huang, Yen-Shuo AU - Huang YS AD - Department of Pathology, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan. FAU - Li, Ching-Chia AU - Li CC AD - Department of Urology, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan. AD - Graduate Institute of Clinical Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan. AD - Department of Urology, School of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan. LA - eng PT - Case Reports DEP - 20240111 PL - United States TA - Urol Case Rep JT - Urology case reports JID - 101626357 PMC - PMC10831150 OTO - NOTNLM OT - EWSR1 OT - Immunohistochemistry OT - Kidney OT - MUC4 OT - Sclerosingepithelioidfibrosarcoma COIS- The authors declare no conflicts of interest. EDAT- 2024/02/02 06:43 MHDA- 2024/02/02 06:44 PMCR- 2024/01/11 CRDT- 2024/02/02 03:59 PHST- 2023/12/14 00:00 [received] PHST- 2024/01/07 00:00 [revised] PHST- 2024/01/10 00:00 [accepted] PHST- 2024/02/02 06:44 [medline] PHST- 2024/02/02 06:43 [pubmed] PHST- 2024/02/02 03:59 [entrez] PHST- 2024/01/11 00:00 [pmc-release] AID - S2214-4420(24)00011-1 [pii] AID - 102657 [pii] AID - 10.1016/j.eucr.2024.102657 [doi] PST - epublish SO - Urol Case Rep. 2024 Jan 11;53:102657. doi: 10.1016/j.eucr.2024.102657. eCollection 2024 Mar.