PMID- 38304118
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20240203
IS  - 2058-4601 (Print)
IS  - 2058-4601 (Electronic)
VI  - 13
IP  - 1
DP  - 2024 Jan
TI  - A multi-institutional assessment of low-dose protocols in chest computed 
      tomography: Dose and image quality.
PG  - 20584601241228220
LID - 10.1177/20584601241228220 [doi]
LID - 20584601241228220
AB  - BACKGROUND: Low-dose CT (LDCT) chest protocols have widespread clinical 
      applications for many indications; as a result, there is a need for protocol 
      assessment prior to standardization. Dalhousie University and Oslo Metropolitan 
      University have a formally established cooperative relationship. PURPOSE: The 
      purpose is to assess radiation dose and image quality for LDCT chest protocols in 
      seven different hospital locations in Norway and Canada. MATERIAL AND METHODS: 
      Retrospective dosimetry data, volumetric CT dose index (CTDI(vol)), and dose 
      length product (DLP) from 240 average-sized patients as well as CT protocol 
      parameters were included in the survey. Effective dose (ED) and size-specific 
      dose estimate (SSDE) were calculated for each examination. For a quantitative 
      image quality analysis, noise, CT number, and signal-to-noise ratio (SNR) were 
      determined for three regions in the chest. The contrast-to-noise ratio (CNR) was 
      calculated for lung parenchyma in comparison to the subcutaneous fat. Differences 
      in dose and image quality were evaluated by a single-factor ANOVA test. A 
      two-sample t-test was performed to determine differences in means between 
      individual scanners. RESULTS: The ANOVA test revealed significant differences (p 
      < .05) in dose values for all scanners, including identical scanner models. 
      Statistically significant differences (p < .05) were determined in mean values of 
      the SNR distributions between the scanners in all three measured regions in the 
      chest, as well as the CNR values. CONCLUSION: The observed variations in dose and 
      image quality measurements, even within the same hospitals and between identical 
      scanner models, indicate a potential for protocol optimization in the involved 
      hospitals in both countries.
CI  - (c) The Author(s) 2024.
FAU - Tonkopi, Elena
AU  - Tonkopi E
AUID- ORCID: 0000-0002-7911-5534
AD  - Department of Diagnostic Radiology, Dalhousie University, Halifax, NS, Canada. 
      RINGGOLD: 3688
AD  - Department of Radiation Oncology, Dalhousie University, Halifax, NS, Canada. 
      RINGGOLD: 3688
AD  - Department of Diagnostic Imaging, Nova Scotia Health Authority, Halifax, NS, 
      Canada. RINGGOLD: 432234
FAU - Tetteh, Mercy Afadzi
AU  - Tetteh MA
AD  - Department of Diagnostic Imaging, Akershus University Hospital, Loerenskog, 
      Norway. RINGGOLD: 60483
FAU - Gunn, Catherine
AU  - Gunn C
AD  - Department of Radiation Oncology, Dalhousie University, Halifax, NS, Canada. 
      RINGGOLD: 3688
AD  - School of Health Sciences, Dalhousie University, Halifax, NS, Canada. RINGGOLD: 
      3688
FAU - Ashraf, Haseem
AU  - Ashraf H
AD  - Department of Diagnostic Imaging, Akershus University Hospital, Loerenskog, 
      Norway. RINGGOLD: 60483
AD  - Medicine Faculty, University of Oslo, Oslo Norway. RINGGOLD: 60504
FAU - Rusten, Sigrid Lia
AU  - Rusten SL
AD  - Health Faculty, Department of Life Sciences and Health, Oslo Metropolitan 
      University Oslo, Norway. RINGGOLD: 60499
FAU - Safi, Perkhah
AU  - Safi P
AD  - Health Faculty, Department of Life Sciences and Health, Oslo Metropolitan 
      University Oslo, Norway. RINGGOLD: 60499
FAU - Tinsoe, Nora Suu
AU  - Tinsoe NS
AD  - Health Faculty, Department of Life Sciences and Health, Oslo Metropolitan 
      University Oslo, Norway. RINGGOLD: 60499
FAU - Colford, Kylie
AU  - Colford K
AD  - School of Health Sciences, Dalhousie University, Halifax, NS, Canada. RINGGOLD: 
      3688
FAU - Ouellet, Olivia
AU  - Ouellet O
AD  - School of Health Sciences, Dalhousie University, Halifax, NS, Canada. RINGGOLD: 
      3688
FAU - Naimi, Salma
AU  - Naimi S
AD  - Department of Diagnostic Imaging, Akershus University Hospital, Loerenskog, 
      Norway. RINGGOLD: 60483
FAU - Johansen, Safora
AU  - Johansen S
AUID- ORCID: 0000-0003-2307-4179
AD  - Health Faculty, Department of Life Sciences and Health, Oslo Metropolitan 
      University Oslo, Norway. RINGGOLD: 60499
AD  - Department of Cancer Treatment, Oslo University Hospital, Oslo, Norway. RINGGOLD: 
      155272
AD  - Health and Social Science Cluster, Singapore Institute of Technology, Singapore.
LA  - eng
PT  - Journal Article
DEP - 20240130
PL  - England
TA  - Acta Radiol Open
JT  - Acta radiologica open
JID - 101651010
PMC - PMC10829498
OTO - NOTNLM
OT  - image quality
OT  - low-dose computed tomography
OT  - radiation dose
COIS- The author(s) declared no potential conflicts of interest with respect to the 
      research, authorship, and/or publication of this article.
EDAT- 2024/02/02 06:43
MHDA- 2024/02/02 06:44
PMCR- 2024/01/30
CRDT- 2024/02/02 04:01
PHST- 2023/09/08 00:00 [received]
PHST- 2024/01/09 00:00 [accepted]
PHST- 2024/02/02 06:44 [medline]
PHST- 2024/02/02 06:43 [pubmed]
PHST- 2024/02/02 04:01 [entrez]
PHST- 2024/01/30 00:00 [pmc-release]
AID - 10.1177_20584601241228220 [pii]
AID - 10.1177/20584601241228220 [doi]
PST - epublish
SO  - Acta Radiol Open. 2024 Jan 30;13(1):20584601241228220. doi: 
      10.1177/20584601241228220. eCollection 2024 Jan.