PMID- 38313103
OWN - NLM
STAT- MEDLINE
DCOM- 20240206
LR  - 20240206
IS  - 1986-5961 (Electronic)
IS  - 0350-199X (Print)
IS  - 0350-199X (Linking)
VI  - 77
IP  - 6
DP  - 2023
TI  - Primary Pulmonary Synovial Sarcoma with Hemothorax: a Case Report.
PG  - 496-499
LID - 10.5455/medarh.2023.77.496-499 [doi]
AB  - BACKGROUND: Synovial sarcoma is a rare and aggressive soft tissue malignancy most 
      commonly arises from periarticular tissue of the extremities. Although several 
      cases in the literature have reported different origins, primary pulmonary 
      synovial sarcoma (PPSS) is an exceedingly rare and underrecognized entity, 
      accounting for 0.5% of all lung malignancies. Clinical presentation includes 
      chest pain, dyspnea, cough, and hemoptysis. The finding of hemothorax is a rare 
      presentation and was barely reported in the literature. Due to its rarity and 
      aggressive nature, the optimal treatment is unclear, while the mainstay remains 
      surgical resection with chemo- and/or radiation therapy. OBJECTIVE: To report a 
      case of hemorrhagic effusion subsequently diagnosed with primary pulmonary 
      synovial sarcoma with the main objective of enriching the literature regarding 
      this rare malignancy. CASE REPORT: A 52-year-old male smoker with a background of 
      coronary artery disease, hypertension, and diabetes mellitus was referred to our 
      hospital. The patient presented with a history of chest pain, dyspnea, and 
      massive right-sided pleural effusion. Laboratory investigations were unremarkable 
      except for anemia. Chest x-ray showed a complete opacity on the right lower zone 
      with right-sided pleural effusion. Thoracentesis was done and revealed 
      hemorrhagic exudative effusion. Computed tomography (CT) scan showed a right 
      heterogeneous lung mass compressing the medial segment of the middle lobe. 
      Subsequently, the patient underwent bronchoscopy, which showed compression and 
      edema on the right middle lobe bronchus with traces of blood coming from the 
      right lower lobe. The patient underwent a right posterolateral thoracotomy, a 
      fungating mass eroding the medial segment of the middle lobe was resected that 
      was diagnosed as high-grade primary pulmonary synovial sarcoma. Radiotherapy was 
      instituted. The patient died after two years due to recurrence. CONCLUSION: PPSS 
      is an aggressive disease with poor prognostic outcomes, and Its presentation is 
      almost similar to other lung malignancies. Meanwhile, there is no definitive 
      management guideline, and most management depends on surgical resection if 
      feasible with adjuvant chemo-radiation therapy.
CI  - (c) 2023 Abdullah Abdulaziz AlQatari, Ayesha Ahmed, Fatima AlHije, Mohammed Sabry, 
      Hatem Elbawab.
FAU - AlQatari, Abdullah Abdulaziz
AU  - AlQatari AA
AD  - Thoracic Surgery Division, Department of General Surgery, King Fahad Hospital of 
      The University, College of Medicine, Imam Abdulrahman Bin Faisal University, 
      Dammam, Saudi Arabia.
FAU - Ahmed, Ayesha
AU  - Ahmed A
AD  - Department of Pathology, King Fahad Hospital of The University, College of 
      Medicine, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia.
FAU - AlHije, Fatima
AU  - AlHije F
AD  - College of Medicine, Imam Abdulrahman Bin Faisal University, Dammam, Saudi 
      Arabia.
FAU - Sabry, Mohammed
AU  - Sabry M
AD  - Associate consultant Thoracic surgery, King Fahad Hospital University, Imam 
      Abdulrahman Bin Faisal University. Assistant Professor of Cardiothoracic Surgery 
      Faculty of Medicine, Menoufia University.
FAU - Elbawab, Hatem
AU  - Elbawab H
AD  - Thoracic Surgery Division, Department of General Surgery, King Fahad Hospital of 
      The University, College of Medicine, Imam Abdulrahman Bin Faisal University, 
      Dammam, Saudi Arabia.
LA  - eng
PT  - Case Reports
PL  - Bosnia and Herzegovina
TA  - Med Arch
JT  - Medical archives (Sarajevo, Bosnia and Herzegovina)
JID - 101635337
SB  - IM
MH  - Male
MH  - Humans
MH  - Middle Aged
MH  - Hemothorax/diagnosis/etiology/therapy
MH  - *Sarcoma, Synovial/complications/diagnosis/surgery
MH  - *Lung Neoplasms/complications/diagnosis/therapy
MH  - Chest Pain/etiology
MH  - Dyspnea/etiology
MH  - *Pleural Effusion
MH  - Lung/pathology
PMC - PMC10834050
OTO - NOTNLM
OT  - Primary pulmonary synovial sarcoma
OT  - care report
OT  - hemothorax
OT  - lung cancer
OT  - lung sarcoma
COIS- There were no conflicts of interest.
EDAT- 2023/01/01 00:00
MHDA- 2024/02/06 06:42
PMCR- 2023/01/01
CRDT- 2024/02/05 04:32
PHST- 2023/10/12 00:00 [received]
PHST- 2023/11/25 00:00 [accepted]
PHST- 2024/02/06 06:42 [medline]
PHST- 2023/01/01 00:00 [pubmed]
PHST- 2024/02/05 04:32 [entrez]
PHST- 2023/01/01 00:00 [pmc-release]
AID - 10.5455/medarh.2023.77.496-499 [doi]
PST - ppublish
SO  - Med Arch. 2023;77(6):496-499. doi: 10.5455/medarh.2023.77.496-499.