PMID- 38314749
OWN - NLM
STAT- MEDLINE
DCOM- 20240207
LR  - 20240211
IS  - 2164-554X (Electronic)
IS  - 2164-5515 (Print)
IS  - 2164-5515 (Linking)
VI  - 20
IP  - 1
DP  - 2024 Dec 31
TI  - Factors associated with HPV vaccine hesitancy among college students: A 
      cross-sectional survey based on 3Cs and structural equation model in China.
PG  - 2309731
LID - 10.1080/21645515.2024.2309731 [doi]
LID - 2309731
AB  - Despite the high effectiveness of HPV vaccines in preventing infection, vaccine 
      hesitancy remains a concern, particularly in China. This study aimed to explore 
      college students' attitudes toward HPV vaccination and identify associated 
      factors. Data was collected through a cross-sectional survey using 
      self-administered questionnaires in four cities from May to June 2022. Chi-square 
      tests and logistic regression analyses were conducted to identify factors. 
      Additionally, an integrated structural equation model (SEM) based on the 3Cs 
      (confidence, convenience, complacency) was developed to understand underlying 
      factors contributing to hesitancy. The results from 2261 valid questionnaires 
      were enlightening. A significant 89.47% (59.4% for females) considered HPV 
      vaccination necessary, with 9.82% remaining neutral and only 0.71% deeming it 
      unnecessary. Factors like higher education, being a medical student, residing in 
      urban areas, having medical insurance, more extraordinary living expenses, a 
      family history of tumors, and a solid understanding of HPV played a role in 
      perceiving the vaccine as necessary. Among the 1438 female respondents, 84.36% 
      had no hesitancy toward HPV vaccination, 13.53% expressed hesitancy, and 2.11% 
      refused vaccination. Factors like age, understanding of HPV, medical staff 
      recommendations, living expenses, and family history influenced hesitancy levels. 
      SEM revealed that the 3Cs significantly affected vaccine hesitancy. Factors like 
      price, booking process, vaccination times, trust in vaccines, medical staff 
      recommendations, efficiency, and risk perception collectively influenced 
      hesitancy. In conclusion, this study found high acceptance of HPV vaccination but 
      acknowledged the complexity of hesitancy factors. It recommends medical staff 
      disseminate scientific knowledge, offer recommendations, simplify booking 
      procedures, and expand vaccination sites to address vaccine hesitancy 
      effectively.
FAU - Chen, Cheng
AU  - Chen C
AD  - School of Medicine and Health Management, Tongji Medical College, Huazhong 
      University of Science and Technology, Wuhan, China.
FAU - Chen, Ting
AU  - Chen T
AD  - School of Public Health, Wuhan University of Science and Technology, Wuhan, 
      China.
FAU - Huang, Mingzhao
AU  - Huang M
AD  - School of Public Health, Wuhan University of Science and Technology, Wuhan, 
      China.
AD  - Hubei Key Laboratory of Occupational Disease Hazard Identification and Control, 
      Wuhan, China.
FAU - Huang, Yan
AU  - Huang Y
AD  - Center for Chinese Public Administration Research, School of Government, Sun 
      Yat-sen University, Guangzhou, China.
FAU - Zhang, Luying
AU  - Zhang L
AD  - School of Public Health, Fudan University, Shanghai, China.
FAU - Li, Pindong
AU  - Li P
AD  - Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of 
      Science and Technology, Wuhan, China.
AD  - Institute of Radiation Oncology, Union Hospital, Tongji Medical College, Huazhong 
      University of Science and Technology, Wuhan, China.
AD  - Hubei Key Laboratory of Precision Radiation, Wuhan, China.
LA  - eng
PT  - Journal Article
DEP - 20240205
PL  - United States
TA  - Hum Vaccin Immunother
JT  - Human vaccines & immunotherapeutics
JID - 101572652
RN  - 0 (Papillomavirus Vaccines)
SB  - IM
MH  - Humans
MH  - Female
MH  - Cross-Sectional Studies
MH  - *Papillomavirus Infections/prevention & control
MH  - Vaccination Hesitancy
MH  - China
MH  - *Students, Medical
MH  - *Papillomavirus Vaccines
MH  - Vaccination
MH  - Health Knowledge, Attitudes, Practice
MH  - Patient Acceptance of Health Care
PMC - PMC10854271
OTO - NOTNLM
OT  - 3C model
OT  - Vaccine hesitancy
OT  - college students
OT  - human papilloma virus
OT  - structural equation model
COIS- No potential conflict of interest was reported by the author(s).
EDAT- 2024/02/05 14:44
MHDA- 2024/02/07 06:42
PMCR- 2024/02/05
CRDT- 2024/02/05 08:43
PHST- 2024/02/07 06:42 [medline]
PHST- 2024/02/05 14:44 [pubmed]
PHST- 2024/02/05 08:43 [entrez]
PHST- 2024/02/05 00:00 [pmc-release]
AID - 2309731 [pii]
AID - 10.1080/21645515.2024.2309731 [doi]
PST - ppublish
SO  - Hum Vaccin Immunother. 2024 Dec 31;20(1):2309731. doi: 
      10.1080/21645515.2024.2309731. Epub 2024 Feb 5.