PMID- 38315767 OWN - NLM STAT- MEDLINE DCOM- 20240304 LR - 20240304 IS - 1944-0057 (Electronic) IS - 1944-0057 (Linking) VI - 41 IP - 3 DP - 2024 Mar TI - Evaluating contamination of seafood purchased from U.S. retail stores by persistent environmental pollutants, pesticides and veterinary drugs. PG - 325-338 LID - 10.1080/19440049.2024.2310128 [doi] AB - Studies have reported health risks associated with seafood contamination, but few data exist on levels in commercially available seafood in the US. To better understand, the magnitude of foodborne exposure and identify vulnerable populations in the US, we measured concentrations of veterinary drugs, persistent organic pollutants (POPs) (polycyclic aromatic hydrocarbons [PAHs], polybrominated diphenyl ethers [PBDEs] and polychlorinated biphenyls [PCBs]), and legacy and current-use pesticides in 46 seafood samples purchased from retail outlets. Measured levels were used to estimate risk based on available maximum residue limits (MRLs) and toxic equivalence (TEQ) factors for analytes. Only seventeen of the 445 analytes were detected, at low substance frequencies. However, half of the samples tested positive for one or more analyte, with total concentrations ranging from below the limit of detection (LOD) to as high as 156 microg/kg wet weight. Based on the risk assessment for individual pesticides and veterinary drugs, the hazard quotients (HQ) were all <1, indicating no risk. However, for the sum of PCB126 and PCB167, two dioxin-like PCBs detected in our samples, the TEQ was nearly two orders of magnitude higher than the WHO limits in one catfish sample. Moreover, vulnerable groups with higher rates of consumption of specific fish types may face higher risks. FAU - Bedi, Megha AU - Bedi M AD - Department of Civil and Environmental Engineering, University of Pittsburgh, Pittsburgh, PA, USA. FAU - Sapozhnikova, Yelena AU - Sapozhnikova Y AD - USDA, Agricultural Research Service, Eastern Regional Research Center, Wyndmoor, PA, USA. FAU - Ng, Carla AU - Ng C AD - Department of Civil and Environmental Engineering, University of Pittsburgh, Pittsburgh, PA, USA. AD - Department of Environmental and Occupational Health, University of Pittsburgh, Pittsburgh, PA, USA. LA - eng PT - Journal Article DEP - 20240205 PL - England TA - Food Addit Contam Part A Chem Anal Control Expo Risk Assess JT - Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment JID - 101485040 RN - 0 (Environmental Pollutants) RN - DFC2HB4I0K (Polychlorinated Biphenyls) RN - 0 (Veterinary Drugs) RN - 0 (Pesticides) SB - IM MH - Animals MH - *Environmental Pollutants MH - *Polychlorinated Biphenyls MH - *Veterinary Drugs MH - *Pesticides MH - Seafood OTO - NOTNLM OT - Risk assessment OT - food-borne exposure OT - pesticides OT - seafood OT - veterinary drugs EDAT- 2024/02/05 18:42 MHDA- 2024/03/04 06:50 CRDT- 2024/02/05 14:03 PHST- 2024/03/04 06:50 [medline] PHST- 2024/02/05 18:42 [pubmed] PHST- 2024/02/05 14:03 [entrez] AID - 10.1080/19440049.2024.2310128 [doi] PST - ppublish SO - Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2024 Mar;41(3):325-338. doi: 10.1080/19440049.2024.2310128. Epub 2024 Feb 5.