PMID- 38329602
OWN - NLM
STAT- MEDLINE
DCOM- 20240503
LR  - 20240520
IS  - 2212-1358 (Electronic)
IS  - 2212-134X (Linking)
VI  - 12
IP  - 3
DP  - 2024 May
TI  - Influence of smoking on patient-reported outcome measures (PROMs) in patients 
      undergoing surgery for adult spinal deformity: a propensity score-matched 
      analysis.
PG  - 819-827
LID - 10.1007/s43390-024-00821-2 [doi]
AB  - PURPOSE: The purpose of this study was to determine the isolated influence of 
      smoking in patient-reported outcome measures (PROMs) for adult spinal deformity 
      (ASD) surgery excluding known tobacco-related complications. METHODS: 
      Retrospective analysis of a prospective multicenter ASD database. Patients 
      operated on ASD with 2 year post-operative follow-up were included. Former 
      smokers (non-active smokers) and patients developing mechanical or infectious 
      complications were excluded. Changes of PROMs over time were analyzed using mixed 
      models for repeated measures (MMRM). Propensity score matching (PSM) (1:1 ratio, 
      caliper 0.10) was performed without replacement using optimum algorithm, 
      tolerance </= 0.001, and estimated with 95% confidence interval (CI). PROMS in both 
      groups were compared by paired t test or Wilcoxon signed-rank test. RESULTS: 692 
      out of 1246 surgical patients met our inclusion criteria. 153 smokers were 
      matched with 153 non-smokers according to age, BMI, number of fused levels, and 
      global tilt. After PSM both groups were homogeneous regarding baseline 
      parameters, surgical data, and complications (mechanical complications and 
      infection excluded). Smokers had worse baseline results for SRS-total, SRS-pain 
      COMI-back, and ODI; smokers also showed worse 2-year outcomes for SRS-total, 
      SRS-function, SRS-pain, SRS-self-image, and ODI. However, no differences between 
      the two groups were found in the improvement from baseline to 2-year follow-up or 
      in the timing of this improvement (MMRM). The proportion of patients reaching the 
      minimal clinically important difference (MCID) after surgery was similar in the 
      two groups, but the proportion of patients reaching patient acceptable symptom 
      state (PASS) was significantly lower in smokers for SRS-Subtotal, SRS-function, 
      and SRS-image. CONCLUSION: Even in the absence of smoking-related complications, 
      smokers had worse PROMs at baseline and 2 years after surgery with less patients 
      achieving PASS, but similar degrees on improvement compared to non-smokers. The 
      proportion achieving MCID was also similar between the two cohorts.
CI  - (c) 2024. The Author(s), under exclusive licence to Scoliosis Research Society.
FAU - Gomez-Rice, Alejandro
AU  - Gomez-Rice A
AUID- ORCID: 0000-0003-1040-7368
AD  - Hospital Universitario Ramon y Cajal, Carretera de Colmenar Viejo Km 9, 100, 
      28034, Madrid, Spain. alexgomezrice@hotmail.com.
FAU - Capdevila-Bayo, Maria
AU  - Capdevila-Bayo M
AD  - Vall d'Hebron Institut de Recerca, Barcelona, Spain.
FAU - Nunez-Pereira, Susana
AU  - Nunez-Pereira S
AD  - Hospital Universitario Vall d'Hebron, Barcelona, Spain.
FAU - Haddad, Sleiman
AU  - Haddad S
AD  - Hospital Universitario Vall d'Hebron, Barcelona, Spain.
FAU - Perez-Grueso, Franciso
AU  - Perez-Grueso F
AD  - Hospital Universitario La Paz, Madrid, Spain.
FAU - Kleinstuck, Frank
AU  - Kleinstuck F
AD  - Schulthess Klinik, Zurich, Switzerland.
FAU - Obeid, Ibrahim
AU  - Obeid I
AD  - CHU Bordeaux, Bordeaux, France.
FAU - Alanay, Ahmet
AU  - Alanay A
AD  - Acibadem Hospital, Istanbul, Turkey.
FAU - Pellise, Ferran
AU  - Pellise F
AD  - Hospital Universitario Vall d'Hebron, Barcelona, Spain.
FAU - Pizones, Javier
AU  - Pizones J
AD  - Hospital Universitario La Paz, Madrid, Spain.
CN  - ESSG European Spine Study Group ESSG
LA  - eng
PT  - Journal Article
PT  - Multicenter Study
DEP - 20240208
PL  - England
TA  - Spine Deform
JT  - Spine deformity
JID - 101603979
SB  - IM
MH  - Humans
MH  - *Patient Reported Outcome Measures
MH  - Male
MH  - Female
MH  - *Propensity Score
MH  - Middle Aged
MH  - *Smoking/adverse effects/epidemiology
MH  - Retrospective Studies
MH  - Adult
MH  - Aged
MH  - Spinal Curvatures/surgery
MH  - Treatment Outcome
OTO - NOTNLM
OT  - Adult spinal deformity
OT  - Patient-reported outcome measures
OT  - Smoking
OT  - Tobacco
EDAT- 2024/02/08 12:43
MHDA- 2024/05/03 12:51
CRDT- 2024/02/08 11:13
PHST- 2023/08/02 00:00 [received]
PHST- 2023/12/31 00:00 [accepted]
PHST- 2024/05/03 12:51 [medline]
PHST- 2024/02/08 12:43 [pubmed]
PHST- 2024/02/08 11:13 [entrez]
AID - 10.1007/s43390-024-00821-2 [pii]
AID - 10.1007/s43390-024-00821-2 [doi]
PST - ppublish
SO  - Spine Deform. 2024 May;12(3):819-827. doi: 10.1007/s43390-024-00821-2. Epub 2024 
      Feb 8.