PMID- 38331359
OWN - NLM
STAT- Publisher
LR  - 20240316
IS  - 1532-8406 (Electronic)
IS  - 0883-5403 (Linking)
DP  - 2024 Feb 7
TI  - What Are the Diagnosis-Specific Thresholds of Minimal Clinically Important 
      Difference and Patient Acceptable Symptom State in Hip Disability and 
      Osteoarthritis Outcome Score After Primary Total Hip Arthroplasty?
LID - S0883-5403(24)00077-9 [pii]
LID - 10.1016/j.arth.2024.01.051 [doi]
AB  - BACKGROUND: This study aimed to determine the minimal clinically important 
      difference (MCID) and Patient Acceptable Symptom State (PASS) thresholds for Hip 
      Disability and Osteoarthritis Outcome Score (HOOS) pain, physical short form 
      (PS), and joint replacement (JR) 1 year after primary total hip arthroplasty 
      stratified by preoperative diagnosis of osteoarthritis (OA) versus non-OA. 
      METHODS: A prospective institutional cohort of 5,887 patients who underwent 
      primary total hip arthroplasty (January 2016 to December 2018) was included. 
      There were 4,184 patients (77.0%) who completed a one-year follow-up. 
      Demographics, comorbidities, and baseline and one-year HOOS pain, PS, and JR 
      scores were recorded. Patients were stratified by preoperative diagnosis: OA or 
      non-OA. Minimal detectable change (MDC) and MCIDs were estimated using a 
      distribution-based approach. The PASS values were estimated using an anchor-based 
      approach, which corresponded to a response to a satisfaction question at one year 
      post surgery. RESULTS: The MCID thresholds were slightly higher in the non-OA 
      cohort versus OA patients. (HOOS-Pain: OA: 8.35 versus non-OA: 8.85 points; 
      HOOS-PS: OA: 9.47 versus non-OA: 9.90 points; and HOOS-JR: OA: 7.76 versus 
      non-OA: 8.46 points). Similarly, all MDC thresholds were consistently higher in 
      the non-OA cohort compared to OA patients. The OA cohort exhibited similar or 
      higher PASS thresholds compared to the non-OA cohort for HOOS-Pain (OA: >/=80.6 
      versus non-OA: >/=77.5 points), HOOS-PS (OA: >/=83.6 versus non-OA: >/=83.6 points), 
      and HOOS-JR (OA: >/=76.8 versus non-OA: >/=73.5 points). A similar percentage of 
      patients achieved MCID and PASS thresholds regardless of preoperative diagnosis. 
      CONCLUSIONS: While MCID and MDC thresholds for all HOOS subdomains were slightly 
      higher among non-OA than OA patients, PASS thresholds for HOOS pain and JR were 
      slightly higher in the OA group. The absolute magnitude of the difference in 
      these thresholds may not be sufficient to cause major clinical differences. 
      However, these subtle differences may have a significant impact when used as 
      indicators of operative success in a population setting.
CI  - Copyright (c) 2024 Elsevier Inc. All rights reserved.
FAU - Emara, Ahmed K
AU  - Emara AK
AD  - Department of Orthopaedic Surgery, Cleveland Clinic, Cleveland, Ohio.
FAU - Pasqualini, Ignacio
AU  - Pasqualini I
AD  - Department of Orthopaedic Surgery, Cleveland Clinic, Cleveland, Ohio.
FAU - Jin, Yuxuan
AU  - Jin Y
AD  - Department of Orthopaedic Surgery, Cleveland Clinic, Cleveland, Ohio.
FAU - Klika, Alison K
AU  - Klika AK
AD  - Department of Orthopaedic Surgery, Cleveland Clinic, Cleveland, Ohio.
FAU - Orr, Melissa N
AU  - Orr MN
AD  - Department of Orthopaedic Surgery, Cleveland Clinic, Cleveland, Ohio.
FAU - Rullan, Pedro J
AU  - Rullan PJ
AD  - Department of Orthopaedic Surgery, Cleveland Clinic, Cleveland, Ohio.
CN  - Cleveland Clinic Arthroplasty Group
AD  - Department of Orthopaedic Surgery, Cleveland Clinic, Cleveland, Ohio.
FAU - Piuzzi, Nicolas S
AU  - Piuzzi NS
AD  - Department of Orthopaedic Surgery, Cleveland Clinic, Cleveland, Ohio.
LA  - eng
PT  - Journal Article
DEP - 20240207
PL  - United States
TA  - J Arthroplasty
JT  - The Journal of arthroplasty
JID - 8703515
SB  - IM
OTO - NOTNLM
OT  - HOOS
OT  - MCID
OT  - Patient Acceptable Symptom State
OT  - THA
OT  - minimal clinically important difference
OT  - osteoarthritis
FIR - Murray, Trevor G
IR  - Murray TG
FIR - Molloy, Robert M
IR  - Molloy RM
FIR - Stearns, Kim L
IR  - Stearns KL
FIR - Krebs, Viktor E
IR  - Krebs VE
FIR - Bloomfield, Michael R
IR  - Bloomfield MR
FIR - Higuera, Carlos A
IR  - Higuera CA
FIR - McLaughlin, John P
IR  - McLaughlin JP
FIR - Deren, Matthew E
IR  - Deren ME
FIR - Surace, Peter
IR  - Surace P
FIR - Barsoum, Wael K
IR  - Barsoum WK
EDAT- 2024/02/09 00:42
MHDA- 2024/02/09 00:42
CRDT- 2024/02/08 19:20
PHST- 2023/11/16 00:00 [received]
PHST- 2024/01/15 00:00 [revised]
PHST- 2024/01/29 00:00 [accepted]
PHST- 2024/02/09 00:42 [pubmed]
PHST- 2024/02/09 00:42 [medline]
PHST- 2024/02/08 19:20 [entrez]
AID - S0883-5403(24)00077-9 [pii]
AID - 10.1016/j.arth.2024.01.051 [doi]
PST - aheadofprint
SO  - J Arthroplasty. 2024 Feb 7:S0883-5403(24)00077-9. doi: 
      10.1016/j.arth.2024.01.051.