PMID- 38332587
OWN - NLM
STAT- MEDLINE
DCOM- 20240409
LR  - 20240426
IS  - 1945-8932 (Electronic)
IS  - 1945-8924 (Print)
IS  - 1945-8932 (Linking)
VI  - 38
IP  - 3
DP  - 2024 May
TI  - The Surprising Effect of Priming on SNOT-22 Results.
PG  - 153-158
LID - 10.1177/19458924241229160 [doi]
AB  - BACKGROUND: Priming is a psychological phenomenon where subconscious cues in the 
      environment impact our behavioral responses in certain situations. Well studied 
      in the worlds of business, marketing, and even politics, it is unclear how the 
      priming phenomenon impacts patient perception of their own disease state nor how 
      they report that perception using tools like the Sinonasal Outcomes Test 
      (SNOT-22), used to measure that perception in chronic rhinosinusitis. OBJECTIVE: 
      To determine the impact of positive or negative priming on self-reported patient 
      perception of their chronic rhinosinusitis disease using the SNOT-22 
      disease-specific quality of life instrument. METHODS: Single-blind, randomized, 
      prospective cohort pilot study of 206 consecutive adult patients with a clinical 
      diagnosis of chronic rhinosinusitis presenting to a university rhinology clinic. 
      Patients were randomized to receive "positive priming" (103) or "negative 
      priming" (103) by reading a passage about the positive or negative aspects of 
      chronic sinusitis and its treatment respectively. Patients were then asked to 
      fill out the SNOT-22 and results between the two groups were compared. RESULTS: 
      The negative priming group had a higher median SNOT-22 score of 49 [IQR = 39] 
      compared to the positive priming groups' score of 22 [IQR = 27], p < 0.0001), a 
      difference of nearly three times the minimal clinical impactful difference 
      (MCID). This effect was consistent regardless of age or sex of the patient. 
      Subgroup analysis revealed a greater impact when priming was performed by the 
      senior male attending regardless of patient age or sex (p < 0.001), while priming 
      performed by the younger female research fellow had greater impact on older 
      patients (>59 years, p = 0.001) and female patients (p = 0.003). CONCLUSIONS: 
      Priming impacts how patient's perceive their chronic rhinosinusitis as determined 
      by the SNOT-22. It is imperative that the rhinologist understand this when using 
      this instrument in research applications and in clinical decision-making for 
      patients.
FAU - Mohammad, Ibtisam
AU  - Mohammad I
AUID- ORCID: 0000-0003-1765-8098
AD  - Department of Otolaryngology-Head & Neck Surgery at the University of North 
      Carolina - Chapel Hill, Chapel Hill, NC, USA.
AD  - Department of Otolaryngology- Head & Neck Surgery at Gazi University, Ankara, 
      Turkey.
FAU - Stack, Taylor
AU  - Stack T
AUID- ORCID: 0000-0002-6014-3308
AD  - Department of Otolaryngology-Head & Neck Surgery at the University of North 
      Carolina - Chapel Hill, Chapel Hill, NC, USA.
FAU - Norris, Meghan
AU  - Norris M
AD  - Department of Otolaryngology-Head & Neck Surgery at the University of North 
      Carolina - Chapel Hill, Chapel Hill, NC, USA.
FAU - Kim, Sulgi
AU  - Kim S
AD  - Department of Otolaryngology-Head & Neck Surgery at the University of North 
      Carolina - Chapel Hill, Chapel Hill, NC, USA.
FAU - Lamb, Meredith
AU  - Lamb M
AD  - Department of Otolaryngology-Head & Neck Surgery at the University of North 
      Carolina - Chapel Hill, Chapel Hill, NC, USA.
FAU - Thorp, Brian D
AU  - Thorp BD
AD  - Department of Otolaryngology-Head & Neck Surgery at the University of North 
      Carolina - Chapel Hill, Chapel Hill, NC, USA.
FAU - Klatt-Cromwell, Christine
AU  - Klatt-Cromwell C
AD  - Department of Otolaryngology-Head & Neck Surgery at the University of North 
      Carolina - Chapel Hill, Chapel Hill, NC, USA.
FAU - Ebert, Charles S Jr
AU  - Ebert CS Jr
AD  - Department of Otolaryngology-Head & Neck Surgery at the University of North 
      Carolina - Chapel Hill, Chapel Hill, NC, USA.
FAU - Kimple, Adam J
AU  - Kimple AJ
AD  - Department of Otolaryngology-Head & Neck Surgery at the University of North 
      Carolina - Chapel Hill, Chapel Hill, NC, USA.
FAU - Senior, Brent A
AU  - Senior BA
AUID- ORCID: 0000-0002-1503-3150
AD  - Department of Otolaryngology-Head & Neck Surgery at the University of North 
      Carolina - Chapel Hill, Chapel Hill, NC, USA.
LA  - eng
GR  - KL2 TR002490/TR/NCATS NIH HHS/United States
PT  - Journal Article
PT  - Randomized Controlled Trial
DEP - 20240208
PL  - United States
TA  - Am J Rhinol Allergy
JT  - American journal of rhinology & allergy
JID - 101490775
SB  - IM
MH  - Adult
MH  - Humans
MH  - Male
MH  - Female
MH  - Sino-Nasal Outcome Test
MH  - Prospective Studies
MH  - Quality of Life
MH  - Pilot Projects
MH  - Single-Blind Method
MH  - *Rhinitis/diagnosis/therapy
MH  - *Sinusitis/diagnosis/therapy
MH  - Chronic Disease
PMC - PMC11000435
OTO - NOTNLM
OT  - SNOT-22
OT  - allergic rhinitis
OT  - chronic rhinosinusitis
OT  - health burden
OT  - outcomes
OT  - priming
OT  - psychology
OT  - quality of life
OT  - septal deviation
OT  - sinus surgery
COIS- Declaration of Conflicting InterestsThe authors declared no potential conflicts 
      of interest with respect to the research, authorship, and/or publication of this 
      article.
EDAT- 2024/02/09 06:43
MHDA- 2024/04/09 06:45
PMCR- 2024/04/08
CRDT- 2024/02/09 02:12
PHST- 2024/04/09 06:45 [medline]
PHST- 2024/02/09 06:43 [pubmed]
PHST- 2024/02/09 02:12 [entrez]
PHST- 2024/04/08 00:00 [pmc-release]
AID - 10.1177_19458924241229160 [pii]
AID - 10.1177/19458924241229160 [doi]
PST - ppublish
SO  - Am J Rhinol Allergy. 2024 May;38(3):153-158. doi: 10.1177/19458924241229160. Epub 
      2024 Feb 8.