PMID- 38339947
OWN - NLM
STAT- Publisher
LR  - 20240210
IS  - 1878-7401 (Electronic)
IS  - 0928-7329 (Linking)
DP  - 2024 Jan 23
TI  - The commercially available oral rinse vs. curcumin photosensitizers in an 
      artificial mouth model mimicking their use after meals on early colonizers single 
      species biofilm: An in vitro study.
LID - 10.3233/THC-231814 [doi]
AB  - BACKGROUND: Commercially available oral rinses contain active ingredients with 
      concentration that is claimed by manufacturers to be effective as antiplaque 
      agent. To date there has been no mention of the effect of oral rinse on the 
      adherence of early plaque colonizers in plaque formation and the concentration to 
      be used before/after meals. OBJECTIVE: The chief aim of the study was to evaluate 
      microbial retention on the salivary pellicle on treatment with oral rinses (CHX & 
      EO)/PS (mimicking after meals use of mouth wash/PS). METHODS: Noordini's 
      Artifical Mouth model was used for developing the single species biofilm with 
      early microbial colonizers of oral biofilm (A. viscosus, Strep. mitis and Strep. 
      sanguinis respectively). The microbial retention on use of oral rinses comprising 
      of CHX and EO as an active ingredients respectively was compared with Curcumin 
      PS. For evaluating the microbial retention, the pellicle with microbial 
      inoculation was developed on the glass beads in the mouth model. Subsequently the 
      respective single specie biofilm was exposed to the mouth wash and PS after 
      inoculation. It mimicked as use of mouth wash/PS after meals. The bacterial count 
      in the dental biofilm was evaluated on serial dilution (CFU/ml). Sterile 
      deionized water was used as a negative control. For qualitative analysis, 
      Scanning electron microscope (SEM) was used to evaluate the microbial count. 
      RESULTS: From the data it was observed that for the treatment of single species 
      experimental biofilm with commercially available mouth rinses (CHX & EO) and PS 
      (curcumin), there was significant retention for S.mitis, S.sanguinis and 
      A.viscosus. There was no significant difference observed between PS and CHX 
      treated single species biofilm. Whereas a significant difference was observed 
      between EO treated biofilms and CHX/PS treated biofilms (p⩽ 0.05). CONCLUSION: It 
      can be concluded from the results that curcumin PS and CHX should not be used 
      after meals whereas EO containing mouth rinse can be used to maintain the oral 
      mocroflora.
FAU - Zeeshan, Tayyaba
AU  - Zeeshan T
AD  - Faculty of Dentistry, Department of Oral and Craniofacial Sciences, University 
      Malaya, Kuala Lumpur, Malaysia.
FAU - Qamar, Zeeshan
AU  - Qamar Z
AD  - Department O&MFS and Diagnostic Sciences, College of Medicine and Dentistry, 
      Riyadh Elm University, Riyadh, Saudi Arabia.
FAU - Abdul, Nishath Sayed
AU  - Abdul NS
AD  - Department of OMFS and Diagnostic Sciences (Oral Pathology), College of Medicine 
      and Dentistry, Riyadh Elm University, Riyadh, Saudi Arabia.
FAU - Soman, Cristalle
AU  - Soman C
AD  - Department of OMFS & DOS, College of Medicine and Dentistry, Riyadh Elm 
      University, Riyadh, Saudi Arabia.
FAU - Bamousa, Badr
AU  - Bamousa B
AD  - Department of Periodontology, College of Medicine and Dentistry, Riyadh Elm 
      University, Riyadh, Saudi Arabia.
FAU - Marrapodi, Maria Maddalena
AU  - Marrapodi MM
AD  - Department of Woman, Child and General and Specialist Surgery, University of 
      Campania "Luigi Vanvitelli", Naples, Italy.
FAU - Cicciu, Marco
AU  - Cicciu M
AD  - Department of General Surgery and Medical-Surgical Specialties, School of 
      Dentistry, University of Catania, Catania, Italy.
FAU - Minervini, Giuseppe
AU  - Minervini G
AD  - Multidisciplinary Department of Medical-Surgical and Dental Specialties, 
      University of Campania "Luigi Vanvitelli", Naples, Italy.
LA  - eng
PT  - Journal Article
DEP - 20240123
PL  - Netherlands
TA  - Technol Health Care
JT  - Technology and health care : official journal of the European Society for 
      Engineering and Medicine
JID - 9314590
SB  - IM
OTO - NOTNLM
OT  - Bacterial retention
OT  - chlorhexidine gluconate
OT  - curcumin photosensitizer
OT  - essential oils
EDAT- 2024/02/10 10:46
MHDA- 2024/02/10 10:46
CRDT- 2024/02/10 05:27
PHST- 2024/02/10 10:46 [medline]
PHST- 2024/02/10 10:46 [pubmed]
PHST- 2024/02/10 05:27 [entrez]
AID - THC231814 [pii]
AID - 10.3233/THC-231814 [doi]
PST - aheadofprint
SO  - Technol Health Care. 2024 Jan 23. doi: 10.3233/THC-231814.