PMID- 38350431
OWN - NLM
STAT- Publisher
LR  - 20240213
IS  - 1421-9751 (Electronic)
IS  - 0008-6312 (Linking)
DP  - 2024 Feb 13
TI  - Intravascular Ultrasound-Guided Versus Angiography-Guided Percutaneous Coronary 
      Intervention for ST Elevation Myocardial Infarction: An Updated Systematic Review 
      and Meta-analysis.
LID - 10.1159/000537682 [doi]
AB  - INTRODUCTION: Intravascular ultrasound (IVUS) provide intra-procedural guidance 
      in optimizing percutaneous coronary interventions (PCI) and have been shown to 
      improve clinical outcomes in stent implantation. However, current data on the 
      benefit of IVUS during PCI in ST elevation myocardial infarction (STEMI) patients 
      is mixed. We performed meta-analysis pooling available data assessing IVUS-guided 
      versus angiography-guided PCI in STEMI patients. METHODS: We conducted a 
      systematic search on PubMed and Embase for studies comparing IVUS versus 
      angiography guided PCI in STEMI. Mantel-Haenszel random effects model was used to 
      calculate risk ratios (RR) with 95% confidence intervals (CI) for outcomes of 
      major adverse cardiovascular events (MACE), death, myocardial infarction (MI), 
      target vessel revascularization (TVR), stent thrombosis (ST) and in-hospital 
      mortality. RESULTS: A total of 8 studies including 336,649 individuals presenting 
      with STEMI were included for the meta-analysis. Follow-up ranged from 11 to 60 
      months. We found significant association between IVUS-guided PCI with lower risk 
      for MACE (RR 0.82, 95% CI 0.76-0.90) compared with angiography-guided PCI. We 
      also found significant association between IVUS-guided PCI with lower risk for 
      death, MI, TVR and in-hospital mortality but not ST. CONCLUSION: In our 
      meta-analysis, IVUS-guided compared with angiography-guided PCI was associated 
      with improved long-term and short-term clinical outcomes in STEMI patients.
CI  - S. Karger AG, Basel.
FAU - Kalsi, Jasmeet
AU  - Kalsi J
FAU - Suffredini, John M
AU  - Suffredini JM
FAU - Koh, Stephanie
AU  - Koh S
FAU - Liu, Jing
AU  - Liu J
FAU - Khalid, Mirza U
AU  - Khalid MU
FAU - Denktas, Ali
AU  - Denktas A
FAU - Alam, Mahboob
AU  - Alam M
FAU - Kayani, Waleed
AU  - Kayani W
FAU - Jia, Xiaoming
AU  - Jia X
LA  - eng
PT  - Systematic Review
DEP - 20240213
PL  - Switzerland
TA  - Cardiology
JT  - Cardiology
JID - 1266406
SB  - IM
EDAT- 2024/02/14 00:44
MHDA- 2024/02/14 00:44
CRDT- 2024/02/13 18:25
PHST- 2023/08/29 00:00 [received]
PHST- 2024/01/24 00:00 [accepted]
PHST- 2024/02/14 00:44 [medline]
PHST- 2024/02/14 00:44 [pubmed]
PHST- 2024/02/13 18:25 [entrez]
AID - 000537682 [pii]
AID - 10.1159/000537682 [doi]
PST - aheadofprint
SO  - Cardiology. 2024 Feb 13. doi: 10.1159/000537682.