PMID- 38353890
OWN - NLM
STAT- MEDLINE
DCOM- 20240425
LR  - 20240425
IS  - 1573-2649 (Electronic)
IS  - 0962-9343 (Linking)
VI  - 33
IP  - 5
DP  - 2024 May
TI  - Multimorbidity patterns and health-related quality of life among 
      community-dwelling older adults: evidence from a rural town in Suzhou, China.
PG  - 1335-1346
LID - 10.1007/s11136-024-03608-0 [doi]
AB  - PURPOSE: The high prevalence of multimorbidity in aging societies has posed 
      tremendous challenges to the healthcare system. The aim of our study was to 
      comprehensively assess the association of multimorbidity patterns and 
      health-related quality of life (HRQOL) among rural Chinese older adults. METHODS: 
      This was a cross-sectional study. Data from 4,579 community-dwelling older adults 
      aged 60 years and above was collected by the clinical examination and 
      questionnaire survey. Information on 10 chronic conditions was collected and the 
      3-Level EQ-5D (EQ-5D-3L) was adopted to measure the HRQOL of older adults. An 
      exploratory factor analysis was performed to determine multimorbidity patterns. 
      Regression models were fitted to explore the associations of multimorbidity 
      patterns with specific health dimensions and overall HRQOL. RESULTS: A total of 
      2,503 (54.7%) participants suffered from multimorbidity, and they reported lower 
      HRQOL compared to those without multimorbidity. Three kinds of multimorbidity 
      patterns were identified including cardiovascular-metabolic diseases, 
      psycho-cognitive diseases and organic diseases. The associations between 
      psycho-cognitive diseases/organic diseases and overall HRQOL assessed by EQ-5D-3L 
      index score were found to be significant (beta = - 0.097, 95% CI - 0.110, - 0.084; 
      beta = - 0.030, 95% CI - 0.038, - 0.021, respectively), and psycho-cognitive 
      diseases affected more health dimensions. The impact of cardiovascular-metabolic 
      diseases on HRQOL was largely non-significant. CONCLUSION: Multimorbidity was 
      negatively associated with HRQOL among older adults from rural China. The 
      presence of the psycho-cognitive diseases pattern or the organic diseases pattern 
      contributed to worse HRQOL. The remarkable negative impact of psycho-cognitive 
      diseases on HRQOL necessiates more attention and relevant medical assistance to 
      older rural adults.
CI  - (c) 2024. The Author(s), under exclusive licence to Springer Nature Switzerland AG.
FAU - Lu, Heng
AU  - Lu H
AD  - School of Public Health, Suzhou Medical College of Soochow University, Suzhou, 
      China.
FAU - Dong, Xing-Xuan
AU  - Dong XX
AD  - School of Public Health, Suzhou Medical College of Soochow University, Suzhou, 
      China.
FAU - Li, Dan-Lin
AU  - Li DL
AD  - School of Public Health, Suzhou Medical College of Soochow University, Suzhou, 
      China.
FAU - Nie, Xin-Yi
AU  - Nie XY
AD  - School of Public Health, Suzhou Medical College of Soochow University, Suzhou, 
      China.
FAU - Wang, Pei
AU  - Wang P
AD  - School of Public Health, Fudan University, Shanghai, China. Wang_p@fudan.edu.cn.
AD  - Key Lab of Health Technology Assessment, National Health Commission of the 
      People's Republic of China (Fudan University), Shanghai, China. 
      Wang_p@fudan.edu.cn.
FAU - Pan, Chen-Wei
AU  - Pan CW
AUID- ORCID: 0000-0003-3362-4613
AD  - School of Public Health, Suzhou Medical College of Soochow University, Suzhou, 
      China. pcwonly@gmail.com.
LA  - eng
GR  - 72274037/National Natural Science Foundation of China/
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20240214
PL  - Netherlands
TA  - Qual Life Res
JT  - Quality of life research : an international journal of quality of life aspects of 
      treatment, care and rehabilitation
JID - 9210257
SB  - IM
MH  - Humans
MH  - *Quality of Life/psychology
MH  - Aged
MH  - Male
MH  - China/epidemiology
MH  - Female
MH  - Cross-Sectional Studies
MH  - *Rural Population/statistics & numerical data
MH  - *Multimorbidity
MH  - Middle Aged
MH  - *Independent Living/psychology
MH  - Surveys and Questionnaires
MH  - Aged, 80 and over
MH  - Chronic Disease/psychology/epidemiology
MH  - Health Status
OTO - NOTNLM
OT  - China
OT  - Health-related quality of life
OT  - Multimorbidity
OT  - Older adults
OT  - Patterns
EDAT- 2024/02/14 12:42
MHDA- 2024/04/25 12:49
CRDT- 2024/02/14 11:13
PHST- 2024/01/11 00:00 [accepted]
PHST- 2024/04/25 12:49 [medline]
PHST- 2024/02/14 12:42 [pubmed]
PHST- 2024/02/14 11:13 [entrez]
AID - 10.1007/s11136-024-03608-0 [pii]
AID - 10.1007/s11136-024-03608-0 [doi]
PST - ppublish
SO  - Qual Life Res. 2024 May;33(5):1335-1346. doi: 10.1007/s11136-024-03608-0. Epub 
      2024 Feb 14.