PMID- 38355200 OWN - NLM STAT- MEDLINE DCOM- 20240418 LR - 20240418 IS - 1467-789X (Electronic) IS - 1467-7881 (Linking) VI - 25 IP - 5 DP - 2024 May TI - Should carbohydrate-modified diets be the first option for weight loss in people with impaired glucose metabolism? A scoping review. PG - e13706 LID - 10.1111/obr.13706 [doi] AB - While the "precision nutrition" movement is at an early stage of development, several investigations have compared low-fat versus carbohydrate (CHO)-modified diets (i.e., low-or-reduced-CHO, low glycemic index/load diets, and high-fiber) in people with normal versus impaired glucose metabolism. The purpose of this scoping review was to summarize evidence in support of the hypothesis that CHO-modified diets are more effective for weight loss among people with impaired glucose metabolism. Fifteen articles were included in this review: seven retrospective analyses of randomized clinical trials and eight prospective randomized clinical trials with prespecified hypotheses related to a diet (low-fat vs. CHO-modified) x phenotype (normal vs. impaired) interaction. Evidence in support of the hypothesis was identified in six of seven retrospective and three of eight prospective studies, which led to a recommendation of CHO-modified diets as a first-line option for people with impaired glucose metabolism. However, the evidence in support of this recommendation is relatively weak, and dietary prescriptions should consider additional contextual information that may influence overall dietary adherence. Additional and rigorous research using innovative randomized experimental approaches is needed for stronger dietary weight loss recommendations based on pretreatment glycemic status. CI - (c) 2024 The Authors. Obesity Reviews published by John Wiley & Sons Ltd on behalf of World Obesity Federation. FAU - Ellison, Katie M AU - Ellison KM AUID- ORCID: 0000-0003-2141-2592 AD - Department of Nutrition Sciences, The University of Alabama at Birmingham, Birmingham, Alabama, USA. FAU - Wyatt, Holly R AU - Wyatt HR AUID- ORCID: 0000-0003-1651-4092 AD - Department of Nutrition Sciences, The University of Alabama at Birmingham, Birmingham, Alabama, USA. FAU - Hill, James O AU - Hill JO AUID- ORCID: 0000-0003-4690-2264 AD - Department of Nutrition Sciences, The University of Alabama at Birmingham, Birmingham, Alabama, USA. FAU - Sayer, R Drew AU - Sayer RD AUID- ORCID: 0000-0002-9488-7030 AD - Department of Family and Community Medicine, The University of Alabama at Birmingham, Birmingham, Alabama, USA. LA - eng GR - OSP000530514/General Mills, Inc./ PT - Journal Article PT - Review DEP - 20240214 PL - England TA - Obes Rev JT - Obesity reviews : an official journal of the International Association for the Study of Obesity JID - 100897395 RN - 0 (Dietary Carbohydrates) RN - 0 (Blood Glucose) SB - IM MH - Humans MH - Prospective Studies MH - *Dietary Carbohydrates/metabolism MH - *Blood Glucose/metabolism MH - Retrospective Studies MH - Weight Loss MH - Diet MH - Diet, Carbohydrate-Restricted OTO - NOTNLM OT - carbohydrate-modified diets OT - impaired glucose metabolism OT - precision nutrition OT - weight loss EDAT- 2024/02/15 00:42 MHDA- 2024/04/18 06:44 CRDT- 2024/02/14 20:52 PHST- 2024/01/08 00:00 [revised] PHST- 2023/05/09 00:00 [received] PHST- 2024/01/13 00:00 [accepted] PHST- 2024/04/18 06:44 [medline] PHST- 2024/02/15 00:42 [pubmed] PHST- 2024/02/14 20:52 [entrez] AID - 10.1111/obr.13706 [doi] PST - ppublish SO - Obes Rev. 2024 May;25(5):e13706. doi: 10.1111/obr.13706. Epub 2024 Feb 14.