PMID- 38357566
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20240216
IS  - 2008-5117 (Print)
IS  - 2008-6830 (Electronic)
IS  - 2008-5117 (Linking)
VI  - 15
IP  - 4
DP  - 2023
TI  - Age and sex-related differences in epidemiology, treatment, and mortality of 
      patients with ST-segment elevation myocardial infarction in Iran.
PG  - 210-217
LID - 10.34172/jcvtr.2023.32887 [doi]
AB  - INTRODUCTION: Few studies have investigated the characteristics of patients with 
      ST elevation myocardial infarction (STEMI) according to age and sex in Iran. This 
      study aims to investigate the risk factors profile, treatment, and mortality of 
      STEMI based on age and sex. METHODS: From 10th June 2016 to December 2019 a total 
      of 2816, STEMI patients referred to the Imam Ali heart center of Kermanshah were 
      included in the study. Profile of the risk factors, epidemiology, treatment and 
      30- day mortality for all cases in the age categories of 18-49, 50-64, and>/=65 
      years were studied. RESULTS: There were 1256 (44.6%) middle-aged STEMI patients, 
      and 2181 (77.45%) were male. The elderly had a longer median door-to-balloon and 
      symptom-to-balloon time and received less primary PCI. In the absence of primary 
      PCI, the rate of 30-day mortality in women was higher than in men, and the 
      mortality rate increased with age. The risk of death in middle-aged women was 
      higher than that of men. Also, in the middle-aged group, after multivariable 
      adjustment, previous bypass surgery, diabetes, and Killip class>/=2 was associated 
      with significant increase in the risk of death. CONCLUSION: The present study 
      showed that young people with STEMI had a high risk of heart failure and anterior 
      infarction compared to the older age groups. Women had more risk factors for 
      STEMI and a higher mortality rate than men. Therefore, there is a need to educate 
      young age groups and women to modify their lifestyles and intervene in the risk 
      factors of heart diseases.
CI  - (c) 2023 The Author(s).
FAU - Darabi, Mehdi
AU  - Darabi M
AUID- ORCID: 0000-0001-6500-8108
AD  - Cardiovascular Research Center, Health Institute, Imam-Ali Hospital, Kermanshah 
      University of Medical Sciences, Kermanshah, Iran.
FAU - Heidari Moghaddam, Reza
AU  - Heidari Moghaddam R
AUID- ORCID: 0000-0002-1143-0159
AD  - Cardiovascular Research Center, Health Institute, Imam-Ali Hospital, Kermanshah 
      University of Medical Sciences, Kermanshah, Iran.
FAU - Godarzi, Farzaneh
AU  - Godarzi F
AD  - Cardiovascular Research Center, Health Institute, Imam-Ali Hospital, Kermanshah 
      University of Medical Sciences, Kermanshah, Iran.
FAU - Karami, Sahar
AU  - Karami S
AUID- ORCID: 0000-0002-1570-3513
AD  - Cardiovascular Research Center, Health Institute, Imam-Ali Hospital, Kermanshah 
      University of Medical Sciences, Kermanshah, Iran.
FAU - Siabani, Soraya
AU  - Siabani S
AUID- ORCID: 0000-0003-2856-0205
AD  - Department of Health Education and Health Promotion, Kermanshah University of 
      Medical Sciences, Kermanshah, Iran.
FAU - Salehi, Nahid
AU  - Salehi N
AUID- ORCID: 0000-0002-4757-6336
AD  - Cardiovascular Research Center, Health Institute, Imam-Ali Hospital, Kermanshah 
      University of Medical Sciences, Kermanshah, Iran.
LA  - eng
PT  - Journal Article
DEP - 20231230
PL  - Iran
TA  - J Cardiovasc Thorac Res
JT  - Journal of cardiovascular and thoracic research
JID - 101528712
PMC - PMC10862036
OTO - NOTNLM
OT  - Mortality
OT  - Risk factors
OT  - STEMI
OT  - Sex
OT  - Treatment
COIS- The authors declare that there were no conflicts of interest. In addition, the 
      authors have no financial gain related to any aspect of the study.
EDAT- 2023/01/01 00:00
MHDA- 2023/01/01 00:01
PMCR- 2023/01/01
CRDT- 2024/02/15 04:28
PHST- 2023/06/19 00:00 [received]
PHST- 2023/12/02 00:00 [accepted]
PHST- 2023/01/01 00:01 [medline]
PHST- 2023/01/01 00:00 [pubmed]
PHST- 2024/02/15 04:28 [entrez]
PHST- 2023/01/01 00:00 [pmc-release]
AID - 10.34172/jcvtr.2023.32887 [doi]
PST - ppublish
SO  - J Cardiovasc Thorac Res. 2023;15(4):210-217. doi: 10.34172/jcvtr.2023.32887. Epub 
      2023 Dec 30.