PMID- 38361905
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20240217
IS  - 2249-4863 (Print)
IS  - 2278-7135 (Electronic)
IS  - 2249-4863 (Linking)
VI  - 12
IP  - 12
DP  - 2023 Dec
TI  - Profile of type 2 diabetes mellitus patients attending family medicine clinic in 
      a rural tribal locality in India.
PG  - 3242-3248
LID - 10.4103/jfmpc.jfmpc_2114_22 [doi]
AB  - OBJECTIVE: Diabetes prevalence has been predicted to reach 578 million worldwide 
      in 2030 and is estimated to increase by 51% (700 million) in 2045. Type 2 
      diabetes mellitus (T2DM) is frequently associated with various cardiovascular 
      (CV) risk factors secondary to associated dyslipidemias and good glycemic control 
      is key for the prevention of long-term CV complications; this study was conducted 
      to assess present glycemic status and lipid profile of the population residing in 
      a rural tribal locality of Jharkhand (India). MATERIALS AND METHODS: This 
      cross-sectional study was conducted as a project for Fellowship in diabetes 
      course by the Department of Endocrinology, DEDU, CMC Vellore. Whole blood and 
      sera were analyzed for fasting blood sugar (FBS), glycated-hemoglobin (HbA1c), 
      total cholesterol (CH), triglycerides (TGs), high-density-lipoprotein-cholesterol 
      (HDL-C), low-density-lipoprotein-cholesterol (LDL-C), and 
      very-low-density-lipoprotein-cholesterol (VLDL-C). A correlation test of HbA1c 
      with lipid ratios and individual lipid indexes was done. RESULTS: The mean Hb1Ac 
      level was uncontrolled as 7.24 +/- 1.80 and, interestingly, was marginally higher 
      [7.31 +/- 1.92 Vs 6.92 +/- 1.16] in patients with T2DM <5 years as compared to those 
      with T2DM >5 years. Mixed dyslipidemias were common with abnormal TG, LDL, VLDL, 
      HDL, and total CH values. Hb1Ac levels showed a significant positive correlation 
      with serum CH, TG, LDL, and VLDL levels, while a significant negative correlation 
      with HDL levels in the study. CONCLUSION: Apart from being a reliable indicator 
      of long-term glycemic control, HbA1c can also be used as a surrogate marker of 
      dyslipidemia, and thus early diagnosis and treatment of dyslipidemia can prevent 
      life-threatening cardiovascular complications that can be particularly useful in 
      resource-poor rural tribal locality settings.
CI  - Copyright: (c) 2023 Journal of Family Medicine and Primary Care.
FAU - Kumar, Sumit
AU  - Kumar S
AD  - Department of Physiology, Government Medical College, Datia, Madhya Pradesh, 
      India.
LA  - eng
PT  - Journal Article
DEP - 20231221
PL  - India
TA  - J Family Med Prim Care
JT  - Journal of family medicine and primary care
JID - 101610082
PMC - PMC10866235
OTO - NOTNLM
OT  - Diabetes
OT  - Hb1Ac
OT  - lipid profile
COIS- There are no conflicts of interest.
EDAT- 2024/02/16 06:42
MHDA- 2024/02/16 06:43
PMCR- 2023/12/01
CRDT- 2024/02/16 03:49
PHST- 2022/10/29 00:00 [received]
PHST- 2023/04/03 00:00 [revised]
PHST- 2023/07/27 00:00 [accepted]
PHST- 2024/02/16 06:43 [medline]
PHST- 2024/02/16 06:42 [pubmed]
PHST- 2024/02/16 03:49 [entrez]
PHST- 2023/12/01 00:00 [pmc-release]
AID - JFMPC-12-3242 [pii]
AID - 10.4103/jfmpc.jfmpc_2114_22 [doi]
PST - ppublish
SO  - J Family Med Prim Care. 2023 Dec;12(12):3242-3248. doi: 
      10.4103/jfmpc.jfmpc_2114_22. Epub 2023 Dec 21.