PMID- 38371651
OWN - NLM
STAT- MEDLINE
DCOM- 20240220
LR  - 20240220
IS  - 1937-8688 (Electronic)
VI  - 47
DP  - 2024
TI  - Left ventricular recovery in an African cohort of patients with peripartum 
      cardiomyopathy.
PG  - 6
LID - 10.11604/pamj.2024.47.6.42083 [doi]
LID - 6
AB  - Peripartum cardiomyopathy (PPCM) is a rare and potentially life-threatening 
      disease associated with pregnancy. There are limited data regarding the outcome 
      of PPCM and its predictive factors in sub-Saharan African patients. We 
      prospectively conducted a double-center (cardiology unit of the department of 
      medicine, Regional Hospital Center of Tenkodogo, Burkina Faso and the department 
      of cardiology of the National Referral Teaching Hospital of N Djamena, Chad) 
      cohort study in patients with PPCM. Patients were consecutively enrolled from 
      January 2015 to December 2017. Outcomes of interest were left ventricular 
      recovery and poor outcome at one year. Ninety-four patients enrolled with a 
      median age of 28 years. At one-year follow-up, 40.5% of them recovered their left 
      ventricular function. Cox multiple regression analysis revealed that higher left 
      ventricle ejection fraction (LVEF), lower natremia and use of betablockers were 
      baseline variables predicting this end-point. Of the entire study population, 
      26.60% exhibited the composite end-point of death (n=15) or remaining in New York 
      Heart Association (NYHA) class III-IV or LVEF < 35%. Predictors of poor outcome 
      were lower LVEF at baseline, hyponatremia and use of digoxin. The current cohort 
      study demonstrated that PPCM in sub-Saharan Africa is associated with limited 
      myocardial recovery and significant rate of poor outcome at one year. Therefore, 
      additional studies are needed to better address the disease.
CI  - Copyright: Dangwe Temoua Naibe et al.
FAU - Dangwe Temoua, Naibe
AU  - Dangwe Temoua N
AD  - Department of Cardiology, National Referral Teaching Hospital of N'Djamena, 
      N'Djamena, Chad.
AD  - Faculty of Human Health Sciences, University of N Djamena, N Djamena, Chad.
FAU - Bamouni, Joel
AU  - Bamouni J
AD  - Superior School of Health Sciences, University of Ouahigouya, Ouahigouya, Burkina 
      Faso.
FAU - Mandi, Dakaboue Germain
AU  - Mandi DG
AD  - Department of General Medicine, Cardiology Unit, Regional Hospital Center of 
      Tenkodogo, Tenkodogo, Burkina Faso.
FAU - Kabore, Elise
AU  - Kabore E
AD  - Department of General Medicine, Cardiology Unit, Regional Hospital Center of 
      Tenkodogo, Tenkodogo, Burkina Faso.
FAU - Allawaye, Lucien
AU  - Allawaye L
AD  - Department of Cardiology, National Referral Teaching Hospital of N'Djamena, 
      N'Djamena, Chad.
AD  - Faculty of Human Health Sciences, University of N Djamena, N Djamena, Chad.
FAU - Langtar, Mianroh Hybi
AU  - Langtar MH
AD  - Department of Cardiology, National Referral Teaching Hospital of N'Djamena, 
      N'Djamena, Chad.
FAU - Adjougoulta, Allamine
AU  - Adjougoulta A
AD  - Department of Cardiology, National Referral Teaching Hospital of N'Djamena, 
      N'Djamena, Chad.
FAU - Doune, Narcisse
AU  - Doune N
AD  - Department of Cardiology, National Referral Teaching Hospital of N'Djamena, 
      N'Djamena, Chad.
FAU - Adam, Ali
AU  - Adam A
AD  - Department of Cardiology, National Referral Teaching Hospital of N'Djamena, 
      N'Djamena, Chad.
FAU - Zakaria, Abdelmadjeib
AU  - Zakaria A
AD  - Department of Cardiology, National Referral Teaching Hospital of N'Djamena, 
      N'Djamena, Chad.
FAU - Relwende Aristide, Yameogo
AU  - Relwende Aristide Y
AD  - Training and Research Unit of Health Sciences, University Professor Joseph 
      Ki-Zerbo, Ouagadougou, Burkina Faso.
FAU - Yibar, Kambire
AU  - Yibar K
AD  - Training and Research Unit of Health Sciences, University Professor Joseph 
      Ki-Zerbo, Ouagadougou, Burkina Faso.
FAU - Kologo, Koudougou Jonas
AU  - Kologo KJ
AD  - Training and Research Unit of Health Sciences, University Professor Joseph 
      Ki-Zerbo, Ouagadougou, Burkina Faso.
FAU - Millogo, Georges Rosario Christian
AU  - Millogo GRC
AD  - Training and Research Unit of Health Sciences, University Professor Joseph 
      Ki-Zerbo, Ouagadougou, Burkina Faso.
FAU - Yameogo, Nobila Valentin
AU  - Yameogo NV
AD  - Training and Research Unit of Health Sciences, University Professor Joseph 
      Ki-Zerbo, Ouagadougou, Burkina Faso.
FAU - Zabsonre, Patrice
AU  - Zabsonre P
AD  - Training and Research Unit of Health Sciences, University Professor Joseph 
      Ki-Zerbo, Ouagadougou, Burkina Faso.
LA  - eng
PT  - Journal Article
DEP - 20240105
PL  - Uganda
TA  - Pan Afr Med J
JT  - The Pan African medical journal
JID - 101517926
SB  - IM
MH  - Pregnancy
MH  - Female
MH  - Humans
MH  - Adult
MH  - Cohort Studies
MH  - Peripartum Period
MH  - Heart Ventricles
MH  - *Cardiomyopathies/epidemiology
MH  - Ventricular Function, Left
MH  - Stroke Volume
MH  - *Puerperal Disorders
MH  - *Pregnancy Complications, Cardiovascular
PMC - PMC10870155
OTO - NOTNLM
OT  - Africa
OT  - Peripartum cardiomyopathy
OT  - outcomes
OT  - recovery
COIS- The authors declare no competing interests.
EDAT- 2024/02/19 06:44
MHDA- 2024/02/20 11:57
PMCR- 2024/01/05
CRDT- 2024/02/19 04:29
PHST- 2023/10/31 00:00 [received]
PHST- 2023/12/12 00:00 [accepted]
PHST- 2024/02/20 11:57 [medline]
PHST- 2024/02/19 06:44 [pubmed]
PHST- 2024/02/19 04:29 [entrez]
PHST- 2024/01/05 00:00 [pmc-release]
AID - PAMJ-47-6 [pii]
AID - 10.11604/pamj.2024.47.6.42083 [doi]
PST - epublish
SO  - Pan Afr Med J. 2024 Jan 5;47:6. doi: 10.11604/pamj.2024.47.6.42083. eCollection 
      2024.