PMID- 38374730
OWN - NLM
STAT- MEDLINE
DCOM- 20240410
LR  - 20240410
IS  - 1536-4801 (Electronic)
IS  - 0277-2116 (Linking)
VI  - 78
IP  - 4
DP  - 2024 Apr
TI  - Growth pattern of paediatric patients affected by cow milk protein allergy fed 
      with rice hydrolyzed formula.
PG  - 909-917
LID - 10.1002/jpn3.12161 [doi]
AB  - OBJECTIVES: Formulas made from hydrolyzed rice proteins (HRPF) are well-tolerated 
      plant-based alternatives to cow's milk protein (CMP)-based formulas for the 
      dietary management of paediatric patients with CMP allergy (CMPA). Growth in 
      patients with CMPA fed with HRPF has been evaluated in several studies with 
      conflicting results. The aim was to evaluate the growth pattern of children with 
      CMPA over a 12-month follow-up period. METHODS: Prospective cohort study 
      evaluating growth patterns in challenge proven CMPA paediatric patients receiving 
      HRPF for 12 months. Outcomes were anthropometry (body weight, body length, head 
      circumference), adherence to the study formula and occurrence of adverse events 
      (AEs). RESULTS: Sixty-six children were included and completed the 12-month 
      study. At baseline, all CMPA patients were weaned. For the entire CMPA pediatric 
      patients' cohort, from baseline to the end of the study period, the growth 
      pattern resulted within the normal range of World Health Organization (WHO) 
      growth references. The formula was well tolerated. Adherence was optimal and no 
      AEs related to HRPF use were reported. CONCLUSIONS: HRPF is well tolerated and 
      can help support healthy growth and development in infants and young children 
      with CMPA. These type of formula can be given with complementary foods in the 
      dietary management of CMPA.
CI  - (c) 2024 The Authors. Journal of Pediatric Gastroenterology and Nutrition published 
      by Wiley Periodicals LLC on behalf of European Society for Pediatric 
      Gastroenterology, Hepatology, and Nutrition and North American Society for 
      Pediatric Gastroenterology, Hepatology, and Nutrition.
FAU - Nocerino, Rita
AU  - Nocerino R
AD  - Department of Translational Medical Science, University of Naples Federico II, 
      Naples, Italy.
AD  - ImmunoNutritionLab at CEINGE Advanced Biotechnologies, University of Naples 
      Federico II, Naples, Italy.
FAU - Coppola, Serena
AU  - Coppola S
AD  - Department of Translational Medical Science, University of Naples Federico II, 
      Naples, Italy.
AD  - ImmunoNutritionLab at CEINGE Advanced Biotechnologies, University of Naples 
      Federico II, Naples, Italy.
FAU - Carucci, Laura
AU  - Carucci L
AD  - Department of Translational Medical Science, University of Naples Federico II, 
      Naples, Italy.
AD  - ImmunoNutritionLab at CEINGE Advanced Biotechnologies, University of Naples 
      Federico II, Naples, Italy.
FAU - Oglio, Franca
AU  - Oglio F
AD  - Department of Translational Medical Science, University of Naples Federico II, 
      Naples, Italy.
AD  - ImmunoNutritionLab at CEINGE Advanced Biotechnologies, University of Naples 
      Federico II, Naples, Italy.
FAU - Cozzolino, Marica
AU  - Cozzolino M
AD  - Department of Translational Medical Science, University of Naples Federico II, 
      Naples, Italy.
AD  - ImmunoNutritionLab at CEINGE Advanced Biotechnologies, University of Naples 
      Federico II, Naples, Italy.
FAU - Masino, Antonio
AU  - Masino A
AD  - Department of Translational Medical Science, University of Naples Federico II, 
      Naples, Italy.
AD  - ImmunoNutritionLab at CEINGE Advanced Biotechnologies, University of Naples 
      Federico II, Naples, Italy.
FAU - Ozen, Gulsum
AU  - Ozen G
AD  - Department of Pediatrics, Ankara Ataturk Sanatoryum Training and Research 
      Hospital, Ankara, Turkey.
FAU - Farnetano, Margherita
AU  - Farnetano M
AD  - Department of Translational Medical Science, University of Naples Federico II, 
      Naples, Italy.
AD  - ImmunoNutritionLab at CEINGE Advanced Biotechnologies, University of Naples 
      Federico II, Naples, Italy.
FAU - Berni Canani, Roberto
AU  - Berni Canani R
AD  - Department of Translational Medical Science, University of Naples Federico II, 
      Naples, Italy.
AD  - ImmunoNutritionLab at CEINGE Advanced Biotechnologies, University of Naples 
      Federico II, Naples, Italy.
AD  - European Laboratory for the Investigation of Food-Induced Diseases, University of 
      Naples Federico II, Naples, Italy.
AD  - Task Force on Microbiome Studies, University of Naples Federico II, Naples, 
      Italy.
LA  - eng
GR  - PE0000003/The study was supported by the Department of Translational Medical 
      Science of the University of Naples "Federico II," Naples, Italy, which received 
      funding from the National Recovery and Resilience Plan, European 
      Union-NextGenerationEU (On Foods-Research and Innovation Network on Food and 
      Nutrition Sustainability, Safety and Security-Working on Foods)/
PT  - Journal Article
DEP - 20240220
PL  - United States
TA  - J Pediatr Gastroenterol Nutr
JT  - Journal of pediatric gastroenterology and nutrition
JID - 8211545
RN  - 0 (Milk Proteins)
RN  - 0 (Protein Hydrolysates)
SB  - IM
MH  - Infant
MH  - Animals
MH  - Female
MH  - Humans
MH  - Child
MH  - Cattle
MH  - Child, Preschool
MH  - *Oryza
MH  - Prospective Studies
MH  - Milk Proteins
MH  - *Milk Hypersensitivity
MH  - Protein Hydrolysates/adverse effects
OTO - NOTNLM
OT  - anthropometric measurements
OT  - food allergy
OT  - malnutrition
EDAT- 2024/02/20 11:50
MHDA- 2024/04/10 06:43
CRDT- 2024/02/20 03:10
PHST- 2024/01/11 00:00 [revised]
PHST- 2023/09/14 00:00 [received]
PHST- 2024/01/22 00:00 [accepted]
PHST- 2024/04/10 06:43 [medline]
PHST- 2024/02/20 11:50 [pubmed]
PHST- 2024/02/20 03:10 [entrez]
AID - 10.1002/jpn3.12161 [doi]
PST - ppublish
SO  - J Pediatr Gastroenterol Nutr. 2024 Apr;78(4):909-917. doi: 10.1002/jpn3.12161. 
      Epub 2024 Feb 20.