PMID- 38376745
OWN - NLM
STAT- MEDLINE
DCOM- 20240405
LR  - 20240419
IS  - 1534-3170 (Electronic)
IS  - 1523-3782 (Linking)
VI  - 26
IP  - 4
DP  - 2024 Apr
TI  - The Global Epidemic of Metabolic Fatty Liver Disease.
PG  - 199-210
LID - 10.1007/s11886-024-02025-6 [doi]
AB  - PURPOSE OF REVIEW: The objective of this manuscript is to examine the current 
      literature on the epidemiology of metabolic dysfunction-associated steatotic 
      liver disease (MASLD), its correlation with cardiovascular disease (CVD) 
      outcomes, as well as to evaluate the update in nomenclature from non-alcoholic 
      liver disease (NAFLD). RECENT FINDINGS: The update of diagnostic criteria from 
      NAFLD to MASLD reduces the stigma associated with alcohol consumption and poor 
      health choices. It also shines a light on the crucial role of cardiometabolic 
      risk factors in disease pathophysiology. The incidence and prevalence of MASLD 
      are projected to increase significantly in the future as the population burden of 
      cardiometabolic risk factors rises. MASLD is also a potent risk factor for 
      developing CVD that should be tackled by using a multi-disciplinary team with a 
      holistic approach. As the new nomenclature for metabolic liver disease is adopted 
      on a global scale, more research is needed to investigate the applicability of 
      findings from previous trials focusing on NAFLD. It is anticipated that the 
      epidemic of MASLD will continue to increase globally, hence the urgent need for 
      therapeutic approaches to reverse this trend.
CI  - (c) 2024. The Author(s), under exclusive licence to Springer Science+Business 
      Media, LLC, part of Springer Nature.
FAU - Lee, Ethan C Z
AU  - Lee ECZ
AD  - Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, 
      Singapore.
FAU - Anand, Vickram V
AU  - Anand VV
AD  - Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, 
      Singapore.
FAU - Razavi, Alex C
AU  - Razavi AC
AD  - Department of Medicine, Division of Cardiology, Emory University School of 
      Medicine, Atlanta, GA, USA.
FAU - Alebna, Pamela L
AU  - Alebna PL
AD  - VCU Health Pauley Heart Center, Virginia Commonwealth University School of 
      Medicine, 1200 East Broad Street, PO Box 980036, Richmond, VA, 23298, USA.
FAU - Muthiah, Mark D
AU  - Muthiah MD
AD  - Division of Gastroenterology & Hepatology, Department of Medicine, National 
      University Hospital, Singapore, Singapore.
FAU - Siddiqui, Mohammad S
AU  - Siddiqui MS
AD  - Stravitz-Sanyal Institute of Liver Disease and Metabolic Health, Virginia 
      Commonwealth University School of Medicine, Richmond, VA, USA.
FAU - Chew, Nicholas W S
AU  - Chew NWS
AD  - Department of Cardiology, National University Heart Centre, National University 
      Health System, Singapore, Singapore.
FAU - Mehta, Anurag
AU  - Mehta A
AD  - VCU Health Pauley Heart Center, Virginia Commonwealth University School of 
      Medicine, 1200 East Broad Street, PO Box 980036, Richmond, VA, 23298, USA. 
      anurag.mehta@vcuhealth.org.
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20240220
PL  - United States
TA  - Curr Cardiol Rep
JT  - Current cardiology reports
JID - 100888969
SB  - IM
MH  - Humans
MH  - *Non-alcoholic Fatty Liver Disease/epidemiology
MH  - Risk Factors
MH  - Alcohol Drinking
MH  - *Cardiovascular Diseases/epidemiology
OTO - NOTNLM
OT  - Cardiometabolic disease
OT  - Cardiovascular disease
OT  - Metabolic-associated fatty liver disease
OT  - Metabolic dysfunction-associated steatotic liver disease
OT  - Non-alcoholic fatty liver disease
EDAT- 2024/02/20 12:52
MHDA- 2024/04/05 06:44
CRDT- 2024/02/20 11:14
PHST- 2024/01/22 00:00 [accepted]
PHST- 2024/04/05 06:44 [medline]
PHST- 2024/02/20 12:52 [pubmed]
PHST- 2024/02/20 11:14 [entrez]
AID - 10.1007/s11886-024-02025-6 [pii]
AID - 10.1007/s11886-024-02025-6 [doi]
PST - ppublish
SO  - Curr Cardiol Rep. 2024 Apr;26(4):199-210. doi: 10.1007/s11886-024-02025-6. Epub 
      2024 Feb 20.