PMID- 38378536 OWN - NLM STAT- MEDLINE DCOM- 20240222 LR - 20240224 IS - 1471-2458 (Electronic) IS - 1471-2458 (Linking) VI - 24 IP - 1 DP - 2024 Feb 20 TI - National and regional prevalence of gestational diabetes mellitus in India: a systematic review and Meta-analysis. PG - 527 LID - 10.1186/s12889-024-18024-9 [doi] LID - 527 AB - BACKGROUND: Gestational diabetes mellitus (GDM) is frequently misdiagnosed during pregnancy. There is an abundance of evidence, but little is known regarding the regional prevalence estimates of GDM in India. This systematic review and meta-analysis aims to provide valuable insights into the national and regional prevalence of GDM among pregnant women in India. METHODS: We conducted an initial article search on PubMed, Scopus, Google Scholar, and ShodhGanga searches to identify quantitative research papers (database inception till 15th June,2022). This review included prevalence studies that estimated the occurrence of GDM across different states in India. RESULTS: Two independent reviewers completed the screening of 2393 articles, resulting in the identification of 110 articles that met the inclusion criteria, which collectively provided 117 prevalence estimates. Using a pooled estimate calculation (with an Inverse square heterogeneity model), the pooled prevalence of GDM in pregnant women was estimated to be 13%, with a 95% confidence interval (CI) ranging from 9 to 16%.. In India, Diabetes in Pregnancy Study of India (DIPSI) was the most common diagnostic criteria used, followed by International Association of Diabetes and Pregnancy Study Groups (IADPSG) and World Health Organization (WHO) 1999. It was observed that the rural population has slightly less prevalence of GDM at 10.0% [6.0-13.0%, I(2)(=)96%] when compared to the urban population where the prevalence of GDM was 12.0% [9.0-16.0%, I(2) = 99%]. CONCLUSIONS: This review emphasizes the lack of consensus in screening and diagnosing gestational diabetes mellitus (GDM), leading to varied prevalence rates across Indian states. It thoroughly examines the controversies regarding GDM screening by analyzing population characteristics, geographic variations, diagnostic criteria agreement, screening timing, fasting vs. non-fasting approaches, cost-effectiveness, and feasibility, offering valuable recommendations for policy makers. By fostering the implementation of state-wise screening programs, it can contribute to improving maternal and neonatal outcomes and promoting healthier pregnancies across the country. CI - (c) 2024. The Author(s). FAU - Mantri, Neha AU - Mantri N AUID- ORCID: 0000-0002-1709-1274 AD - School of Public Health, AIIMS, Jodhpur, India. FAU - Goel, Akhil Dhanesh AU - Goel AD AUID- ORCID: 0000-0002-6156-7903 AD - Department of Community Medicine & Family Medicine, AIIMS, Jodhpur, India. doc.akhilgoel@gmail.com. FAU - Patel, Mamta AU - Patel M AUID- ORCID: 0000-0002-4659-3687 AD - School of Public Health, AIIMS, Jodhpur, India. FAU - Baskaran, Pritish AU - Baskaran P AD - Department of Community Medicine & Family Medicine, AIIMS, Jodhpur, India. FAU - Dutta, Gitashree AU - Dutta G AD - Department of Community Medicine & Family Medicine, AIIMS, Jodhpur, India. FAU - Gupta, Manoj Kumar AU - Gupta MK AUID- ORCID: 0000-0002-5367-5795 AD - Department of Community Medicine & Family Medicine, AIIMS, Jodhpur, India. FAU - Yadav, Vikas AU - Yadav V AD - ICMR-NIREH, Bhopal, Madhya Pradesh, India. FAU - Mittal, Madhukar AU - Mittal M AUID- ORCID: 0000-0002-6919-5614 AD - Department of Endocrinology and Metabolism, AIIMS, Jodhpur, India. FAU - Shekhar, Shashank AU - Shekhar S AD - Department of Obstetrics and Gynaecology, AIIMS, Jodhpur, India. FAU - Bhardwaj, Pankaj AU - Bhardwaj P AUID- ORCID: 0000-0001-9960-3060 AD - Department of Community Medicine & Family Medicine, Academic Head, School of Public Health, AIIMS, Jodhpur, India. LA - eng PT - Journal Article PT - Meta-Analysis PT - Systematic Review DEP - 20240220 PL - England TA - BMC Public Health JT - BMC public health JID - 100968562 SB - IM MH - Infant, Newborn MH - Pregnancy MH - Female MH - Humans MH - *Diabetes, Gestational/diagnosis/epidemiology MH - Prevalence MH - Glucose Tolerance Test MH - Fasting MH - India/epidemiology MH - Pregnancy Outcome/epidemiology PMC - PMC10877914 OTO - NOTNLM OT - DIPSI OT - Diagnosis OT - Gestational diabetes mellitus OT - Glucose tolerance test OT - IADPSG OT - Pregnancy complications COIS- The authors declare no competing interests. EDAT- 2024/02/21 11:14 MHDA- 2024/02/22 12:12 PMCR- 2024/02/20 CRDT- 2024/02/20 23:36 PHST- 2023/07/16 00:00 [received] PHST- 2024/02/06 00:00 [accepted] PHST- 2024/02/22 12:12 [medline] PHST- 2024/02/21 11:14 [pubmed] PHST- 2024/02/20 23:36 [entrez] PHST- 2024/02/20 00:00 [pmc-release] AID - 10.1186/s12889-024-18024-9 [pii] AID - 18024 [pii] AID - 10.1186/s12889-024-18024-9 [doi] PST - epublish SO - BMC Public Health. 2024 Feb 20;24(1):527. doi: 10.1186/s12889-024-18024-9.